Female Complete Saliva Hormone Profile
Understand your hormone levels and take informed steps towards better wellbeing.
Changes in your periods, energy, sleep, mood or libido can leave you feeling unlike yourself. The Female Complete Saliva Hormone Profile measures key sex hormones alongside morning and bedtime cortisol, providing useful information to explore these concerns with specialist interpretation.
Collect two saliva samples at home—no needles or clinic appointment required.
| Test Information | Details |
|---|---|
| Test ID | S-145 |
| Sample Type | Saliva—two samples collected on the same day |
| Test Panel | LCMS Hormones Estradiol, Progesterone, Testosterone, DHEAS, Morning Cortisol, and Bed Time Cortisol. |
| Technology | LC-MS/MS hormone profile |
| Laboratory | ZRT Laboratory—CLIA certified |
| Results Time | 3–5 working days after the laboratory receives your samples |
| Interpretation | Hormone specialist interpretation included |
| Suitable For | Adults and children |
| Collection | At home—no clinic visit required |
| Kit Validity | Use within 12 months of purchase |
What Does This Test Measure?
The panel measures estradiol, progesterone, testosterone, DHEAS, morning cortisol, and bed time cortisol.
| Hormone | What It Adds to Your Assessment |
|---|---|
| Estradiol (E2) | Information about a key oestrogen, interpreted alongside menstrual stage, symptoms and hormone use |
| Progesterone | Context for assessing reproductive hormone levels, particularly when collected at the appropriate point in your cycle |
| Testosterone | An assessment of an androgen relevant to women’s sexual wellbeing and physical health |
| DHEAS | Measurement of an adrenal androgen that contributes to the production of other sex hormones |
| Morning Cortisol | Your cortisol level at the beginning of your waking day |
| Bedtime Cortisol | Your cortisol level before sleep, allowing comparison with your morning result |
How Can This Test Help You?
Explore your hormonal picture
Measuring several hormones together gives you more information than a single hormone result. Your report helps you understand your levels alongside concerns such as menstrual changes, reduced libido, fatigue or changes in wellbeing.
Add context to perimenopause and menopause symptoms
If you are experiencing changes in your cycle, sleep or sexual wellbeing, the results provide a snapshot of the hormones measured. Your specialist can interpret these findings alongside your age, menstrual history and symptoms.
Compare morning and bedtime cortisol
Two cortisol samples show your levels at the start and end of your waking day. This adds useful context when discussing morning tiredness, difficulty winding down or disrupted sleep. A four-point profile offers additional detail about levels during the daytime.
Receive guidance on your next steps
Specialist interpretation helps make your report understandable and useful. Your results can support focused discussions about your symptoms, sleep routines, stress management and whether further assessment would be helpful.
Establish a baseline
Your report records your hormone levels at the time of collection. Where repeat testing is appropriate, it provides a starting point for comparing changes over time.
Who Should Consider This Test?
This profile may be of interest to women experiencing:
- Changes in menstrual regularity or PMS symptoms
- Perimenopausal or menopausal changes
- Reduced libido or changes in sexual wellbeing
- Persistent tiredness or reduced energy
- Poor sleep or difficulty winding down at bedtime
- Mood changes, irritability or difficulty concentrating
- Concerns about how stress and hormone levels may relate to their wellbeing
It is also an option for women seeking a hormone baseline or discussing treatment monitoring with their practitioner. For children, testing should address an age-appropriate clinical question.
Why Choose Saliva Hormone Testing?
Saliva collection makes it convenient to measure hormones at home, including cortisol at different times of day. It requires no blood draw and can be particularly helpful for people who prefer a non-invasive collection method.
ZRT offers LC-MS/MS saliva profiles capable of measuring low oestrogen concentrations and considers age, menstrual status and hormone supplementation when interpreting relevant results.
How It Works
Order your kit
Receive the collection materials and instructions at your chosen address.
Choose your collection day
If you have periods, use the cycle-timing guidance below. Children and women who are not menstruating can collect on any day, following any applicable hormone-treatment instructions.
Collect your morning sample
Begin collecting into the large 10 mL tube within 30 minutes of waking.
Collect your bedtime sample
Collect into one small 5 mL tube before bed on the same day.
Return your samples
Complete your requisition form and follow the shipping instructions provided.
Receive your report
Your results and specialist interpretation are emailed within 3–5 working days after laboratory receipt.
When Should Women Collect Their Samples?
For estradiol, progesterone and testosterone testing, the supplied ZRT instructions recommend the following timing:
| Your Cycle or Situation | When to Collect |
|---|---|
| Regular cycles lasting 23–26 days | Day 17, 18 or 19 |
| Regular cycles lasting 27–30 days | Day 21, 22 or 23 |
| Regular cycles lasting 31–34 days | Day 25, 26 or 27 |
| Longer or shorter regular cycles | 5–7 days before your next expected period |
| Infrequent or unpredictable periods | Any non-bleeding day |
| Postmenopausal or otherwise not menstruating | Any day |
| Children | Any day |
| Using hormone treatment | Follow the treatment-specific instructions in Section 3 |
Day 1 is the first day of menstrual flow, not spotting. Both saliva samples should be collected on your chosen day.
Read Before Collecting Your Samples
Download the Saliva Collection Instructions PDF and follow the S-145 two-sample schedule.
Key points from the instructions:
- Avoid food, drinks other than water, and toothbrushing before your morning sample and for two hours before your bedtime sample.
- Rinse your mouth with water, then wait five minutes before collecting.
- Fill each tube at least halfway, excluding bubbles.
- Label both tubes with your name, collection date and time.
- Record your medications, hormone treatments and menstrual information on the requisition form.
- Freeze samples if they will not be shipped within 24 hours.
The PDF also explains preparation, supplements, hormone-treatment timing and how to avoid sample contamination.
What You Receive
- Estradiol, progesterone, testosterone and DHEAS results
- Separate morning and bedtime cortisol results
- Laboratory reference ranges
- Specialist interpretation considering the information you provide
- Personalised next-step recommendations
- Laboratory analysis included in the price
Return postage to the laboratory is your responsibility.
Why We Use ZRT Laboratory
Your samples are analysed by ZRT Laboratory, a CLIA-certified diagnostic laboratory specialising in hormone and wellness testing. ZRT provides results designed to support informed decisions about patient care.
Through Hormone Lab UK, you can access this testing from home, with specialist interpretation included.
Not Sure Which Test Is Right for You?
Email info@hormonelab.co.uk with your age, symptoms, menstrual status, medications and current treatments. We will forward your enquiry to our specialist team and respond within 24 hours.
Frequently Asked Questions
Does this test measure five or six hormones?
It measures five different hormones. Cortisol is measured twice, producing six individual results: estradiol, progesterone, testosterone, DHEAS, morning cortisol and bedtime cortisol.
How many samples do I need?
Two samples on the same day: one in the large tube upon waking and one in a small tube before bed. Your kit may contain additional tubes that are not needed for S-145.
How does this differ from Female Saliva Hormone Profile I?
Profile I, S-124, measures the same five hormones using a morning sample. S-145 adds bedtime cortisol, allowing comparison between morning and bedtime levels.
Can I use this test after menopause?
Yes. Women who are no longer menstruating can collect on any day. If you use HRT, also follow the treatment-specific collection guidance.
Can I use this test while taking HRT?
It may be suitable, depending on the type and route of treatment. Follow Section 3 of the collection instructions and record all hormones used. Continue prescribed treatment as directed. The instructions recommend an alternative sample type for troches or sublingual hormone therapy.
What if my periods are irregular?
For infrequent or unpredictable cycles, the instructions advise collecting on any non-bleeding day. Include your menstrual history on the requisition form to support interpretation.
Is the test suitable for children?
Yes, provided the required saliva volume can be collected. Include the child’s age and the reason for testing so results can be considered in the appropriate context.
Does the price include laboratory analysis?
Yes. Laboratory analysis and specialist interpretation are included. Return postage is paid separately.
How long is the kit valid for?
Use the kit within 12 months of purchase.
Where can I find the collection instructions?
Download the Saliva Collection Instructions PDF. Follow the S-145 schedule, together with the menstrual-cycle and hormone-use guidance relevant to you.
