Elite Female Saliva Hormone Profile
Explore your hormone levels with eight results, two simple saliva samples and specialist interpretation.
Changes in your periods, energy, sleep, mood or libido can make it difficult to understand what your body needs. The Elite Female Saliva Hormone Profile measures three oestrogens alongside progesterone, testosterone, DHEAS, and morning and bedtime cortisol—giving you a broader hormonal picture to support informed next steps.
Collect your samples at home, without needles or a clinic appointment.
| Test Information | Details |
|---|---|
| Test ID | S-146 |
| Sample Type | Saliva |
| Test Panel | LCMS Hormones 7 with 2-Point Cortisol |
| Technology | LC-MS/MS hormone profile |
| Markers Reported | 8 results—7 different hormones, with cortisol measured twice |
| Samples Required | Two: upon waking and before bed |
| Results Time | 3–5 working days after laboratory receipt |
| Laboratory | ZRT Laboratory—CLIA certified |
| Interpretation | Hormone specialist interpretation included |
| Suitable For | Adults and children |
| Collection | At home—no clinic visit required |
| Kit Validity | Use within 12 months of purchase |
What Does This Test Measure?
ZRT lists S-146 as LCMS Hormones 7 with 2-Point Cortisol. The panel provides eight individual results, including separate morning and bedtime cortisol measurements.
| Marker | What It Adds to Your Hormone Profile |
|---|---|
| Estrone (E1) | Extends your oestrogen assessment beyond estradiol alone |
| Estradiol (E2) | Measures a key oestrogen, interpreted alongside menstrual stage, symptoms and hormone use |
| Estriol (E3) | Completes the three-oestrogen assessment |
| Progesterone | Adds information about reproductive hormone levels when collected at the appropriate cycle stage |
| Testosterone | Measures an androgen relevant to women’s sexual wellbeing and physical health |
| DHEAS | Measures an adrenal androgen that contributes to the production of other sex hormones |
| Morning Cortisol | Measures cortisol at the beginning of your waking day |
| Bedtime Cortisol | Allows comparison with your morning cortisol level |
How Can This Test Help You?
Get a broader picture of your hormones
This profile includes all three oestrogens—estrone, estradiol and estriol—alongside other key hormones. It gives your specialist more laboratory information to consider when reviewing your symptoms, menstrual history and current treatments.
Explore changes in menstrual and menopausal wellbeing
If you are experiencing PMS, changing periods or symptoms around perimenopause and menopause, your results provide a snapshot of the measured hormones. Interpretation places these findings in the context of your life stage and collection timing.
Understand your morning and bedtime cortisol levels
For women who wake feeling tired or struggle to wind down at night, comparing cortisol at these two times adds useful information to discussions about sleep and energy. This is a morning-to-bedtime comparison, rather than a full four-point daily cortisol profile.
Make your next steps more focused
Specialist interpretation helps you understand what your results mean and which findings deserve attention. Recommendations can support discussions about lifestyle, sleep, stress management, further testing or a review of current care.
Create a baseline for future comparison
Your report records your hormone levels at the time of testing. Where repeat testing is appropriate, it provides a starting point for assessing changes over time.
Related Symptoms
This profile may be of interest to women experiencing:
- Irregular periods or changes in their usual menstrual pattern
- PMS, including mood changes, bloating or breast tenderness
- Perimenopausal or menopausal symptoms
- Reduced libido or changes in sexual wellbeing
- Persistent tiredness or reduced energy
- Poor sleep, night waking or difficulty winding down
- Mood changes, irritability or difficulty concentrating
- Changes in wellbeing during periods of sustained stress
These symptoms provide context for interpretation; the test helps assess the hormones measured rather than establishing a single explanation for every symptom.
Did You Know?
This profile measures three oestrogens, not just estradiol. Estrone, estradiol and estriol are reported separately, alongside progesterone, testosterone, DHEAS and two cortisol results.
ZRT’s LC-MS/MS saliva testing can measure low oestrogen concentrations, including those found in children and people with low hormone levels. This analytical sensitivity supports detailed hormone measurement from a non-invasive sample.
Who Should Consider This Test?
The Elite Female Saliva Hormone Profile may suit women who want:
- A broader oestrogen assessment alongside other sex hormones
- Hormone results to discuss alongside menstrual or menopausal concerns
- Morning and bedtime cortisol measurements alongside their sex hormone profile
- A baseline for future comparison
- Specialist interpretation to help prioritise next steps
- Testing to support a practitioner-led review of hormone treatment, where appropriate for the treatment used
The collection method is also suitable for children who can provide the required saliva volume. Their results should be considered against an age-appropriate reason for testing.
Why Choose Saliva Hormone Testing?
Saliva collection is convenient, non-invasive and easy to complete at home. It also allows samples to be collected at specific times, making it practical to compare morning and bedtime cortisol.
ZRT considers information such as age, menstrual status and hormone supplementation when interpreting relevant results. Providing these details on your requisition form helps make the report more useful to you.
How It Works
Order your kit
Receive your collection materials and instructions at your chosen address.
Choose your collection day
Follow the menstrual-cycle guidance below and any applicable hormone-treatment instructions.
Collect your morning sample
Begin collecting into the large 10 mL tube within 30 minutes of waking.
Collect your bedtime sample
Collect into one small 5 mL tube before bed on the same day.
Return your samples
Complete your requisition form and follow the return shipping instructions provided.
Receive your results
Your report and specialist interpretation are emailed within 3–5 working days after the laboratory receives your samples.
When Should You Collect Your Samples?
The supplied ZRT instructions give the following collection schedule for women testing reproductive hormones:
| Your Cycle or Situation | Collection Timing |
|---|---|
| Regular cycles lasting 23–26 days | Day 17, 18 or 19 |
| Regular cycles lasting 27–30 days | Day 21, 22 or 23 |
| Regular cycles lasting 31–34 days | Day 25, 26 or 27 |
| Longer or shorter regular cycles | 5–7 days before your next expected period |
| Infrequent or unpredictable periods | Any non-bleeding day |
| Postmenopausal or otherwise not menstruating | Any day |
| Children | Any day |
| Using hormone treatment | Follow Section 3 of the collection instructions |
Day 1 is the first day of menstrual flow, not spotting. Collect both samples on your chosen day.
Saliva Collection Instructions
Download the Saliva Collection Instructions PDF and follow the S-146 two-sample schedule.
For successful collection:
- Avoid food, drinks other than water, and toothbrushing before your morning sample and for two hours before your bedtime sample.
- Rinse your mouth with water and wait five minutes before collecting.
- Fill each tube at least halfway, excluding bubbles.
- Label each tube with your name, collection date and time.
- Record medications, hormone treatments and menstrual information on your requisition form.
- Freeze samples if they will not be shipped within 24 hours.
Read the full PDF before starting. It also covers preparation, supplements, hormone-treatment timing and avoiding sample contamination.
What You Receive
- Eight individual results: estrone, estradiol, estriol, progesterone, testosterone, DHEAS, morning cortisol and bedtime cortisol
- Laboratory reference ranges
- Specialist interpretation considering the information supplied
- Personalised next-step recommendations
- Your report delivered by email
- Laboratory analysis included in the price
Return postage to the laboratory is your responsibility.
Why We Use ZRT Laboratory
Your samples are analysed by ZRT Laboratory, a CLIA-certified diagnostic laboratory specialising in hormone and wellness testing. Its laboratory services support informed assessment and decisions about patient care.
Through Hormone Lab UK, you can access this testing from home, with specialist interpretation included.
Not Sure Which Test Is Right for You?
Email info@hormonelab.co.uk with your age, symptoms, menstrual status, medications and any current treatments. We will forward your enquiry to our specialist team and respond within 24 hours.
Frequently Asked Questions
What are the eight markers?
Estrone, estradiol, estriol, progesterone, testosterone, DHEAS, morning cortisol and bedtime cortisol. These represent seven different hormones with cortisol measured twice.
How many saliva samples do I need?
Two samples on the same day: one in the large tube upon waking and one in a small tube before bed. Additional tubes supplied in the kit are not required for S-146.
How does this differ from Female Complete Saliva Hormone Profile?
The Female Complete profile, S-145, measures estradiol, progesterone, testosterone, DHEAS and two cortisol levels. The Elite profile, S-146, adds estrone and estriol, expanding the oestrogen assessment.
How does this differ from Female Hormone Profile III?
Profile III, S-125, measures the same seven hormones using a morning sample. The Elite profile adds bedtime cortisol, providing a morning-to-bedtime comparison.
Can I use this test after menopause?
Yes. Women who are no longer menstruating can collect on any day. If you use HRT, also follow the treatment-specific instructions.
Can I use this test while taking HRT?
It may be suitable, depending on the treatment and how it is administered. Follow Section 3 of the collection PDF, continue prescribed treatment as directed and record all hormone use. The instructions recommend an alternative sample type for troches or sublingual hormone therapy.
What if my periods are irregular?
For infrequent or unpredictable cycles, collect on any non-bleeding day and include your menstrual history on the requisition form.
Is the test suitable for adults and children?
Yes, provided the required saliva volume can be collected. Include the person’s age and reason for testing to support appropriate interpretation.
Does the price include laboratory analysis?
Yes. Laboratory analysis and specialist interpretation are included. Return postage is paid separately.
How long is the kit valid for?
Use the kit within 12 months of purchase.
Where can I find the collection instructions?
Download the Saliva Collection Instructions PDF. Follow the S-146 morning and bedtime schedule, together with the cycle-timing and hormone-use guidance relevant to you.
