Add on Cardio ProfileAdd on Insulin (In) Fasting , Add on High-Sensitivity C-Reactive Protein ( hsCRP), Add on Triglycerides (TG), Add on Total Cholesterol (CH), Add on LDL Cholesterol (LDL), Add on Hemoglobin A1c (HbA1c), Add on VLDL Cholesterol (VLDL), Add on HDL Cholesterol (HDL), Add on Luteinizing hormone (LH) in blood spots in men and women.
Test Result: You will receive your test result 3-5 working days after the laboratory receives your sample. You will see your hormone levels in graphics and numbers on your test result. You will also see laboratory comments by Hormone Specialist PhD Dr in the comments: you will find Dr analysis of your hormone levels and what to do next.
- Collect samples from the comfort of your home and post them to our lab.
- The test must be used within 12 months after the purchase date.
- The test kit includes a laboratory fee: no additional laboratory cost and tax.
- Customers are responsible for shipping their samples to the laboratory.
Hormones play an important role in athletic performance. The Elite Athlete Metrics Profile allows the identification of hormone imbalances or vitamin D deficiency that can affect performance, increase injury risk, or prevent an athlete from competing at their highest level. It is best to start with a baseline before rigorous training begins and to track hormones throughout a training regimen to look for big changes that can indicate problems and to make sure that hormones are optimally balanced right before a competition.
The sex hormones and cortisol are tested in saliva, allowing a diurnal assessment of cortisol production at 4-time points during the day. A full thyroid assessment in blood spot is included, and vitamin D.
The optional cardio panel gives athletes a broader glimpse into overall health through measurement of triglycerides, cholesterol and insulin. Optional LH helps assess exercise-induced amenorrhea in female athletes, as well as excessive testosterone supplementation or painkiller use that can suppress LH, while hs-CRP gives an indication of inflammation in the body.
Who benefits from Elite Athlete Profile Testing?
- Train for competitions
- Compete at a high level
- Feel like they are “hitting a wall”
- Suffer from nagging or persistent injuries
- Are interested in seeing how their workouts affect their hormones
Why do you need this test?
Estradiol and progesterone
Sex Hormone Binding Globulin (SHBG)
Dehydroepiandrosterone DHEA-S (DS)
Free T4, free T3, TSH, and TPO
Vitamin D (D2, D3)
Vitamin D deficiency is common in obesity and is particularly associated with hyperinsulinemia and visceral fat. Whether by cause or effect, identifying and correcting vitamin D2 and D3 deficiency may improve insulin sensitivity.
Most people are familiar with vitamin D’s role in preventing rickets in children and in helping the body absorb calcium from the diet.
Recently, research has shown that vitamin D is important in protecting the body from a wide range of diseases. Disorders linked with vitamin D deficiency include:
- Cardiovascular disease
- Several forms of cancer
- Some autoimmune diseases such as multiple Sclerosis
- Rheumatoid Arthritis
- Type I Diabetes & Type II Diabetes
- Breast and Colon Cancer (linked to Vitamin D Deficiency)
- Depression and even schizophrenia
Vitamin D is actually a prohormone and not technically a vitamin: a vitamin is defined as a substance that is not made naturally by the body but must be supplied in the diet to maintain life processes. But in fact, we make most of our vitamin D by the action of ultraviolet light (sunlight) on the vitamin D originator that is found in our skin. We only get very small amounts of vitamin D from our diet, although increasingly it is added to foods eaten by children, in an attempt to prevent rickets in the population
Insulin (IN) Fasting: High fasting insulin levels are a good indicator of insulin resistance, whether or not the patient shows glucose intolerance. Insulin resistance occurs when the cellular response to the presence of insulin is impaired, resulting in a reduced ability of tissues to take up glucose for energy production. Chronically high insulin levels are seen as the body attempts to normalize blood sugar levels. The normal range for fasting insulin is 1 – 15 μIU/ml, but levels between 1 and 8 μIU/mL are optimal.
Blood levels of insulin 2 hours after a meal are now becoming an important indicator of both diabetes progression and cardiovascular disease risk. In non-diabetics, elevated postprandial insulin may be a better marker of cardiovascular disease risk than fasting insulin. In individuals with diabetes, postprandial levels become lower as diabetes progresses and beta-cell responsiveness deteriorates, indicating worsening of blood sugar control. In nondiabetics, whose pancreatic beta-cell function is normal, insulin levels usually return to normal (1-15 μIU/mL) within 2 hours after eating a typical breakfast meal. Elevated postprandial insulin levels have been strongly linked with coronary artery disease risk in non-diabetics.
Total Cholesterol (CH): Cholesterol is required by the body as a precursor to steroid hormone synthesis and as a component of cell membranes. However, in excessive amounts, it is a strong component of coronary heart disease risk because of its contribution to coronary atherosclerosis. Atherosclerotic plaque is largely composed of cholesterol. As with other risk factors, high blood cholesterol levels are more significant when other cardiometabolic parameters are already abnormal, or in patients who already have diabetes or cardiovascular disease. The current National Cholesterol Education Program recommendations for total cholesterol levels are: <200 mg="" dl="borderline" 200="" -="" 239="" high="" data-mce-fragment="1">240 mg/dL = high.
High-Sensitivity C-Reactive Protein (hs-CRP): C-reactive protein (CRP) is an established marker of inflammation and has recently been suggested to be an important contributor to the pro-inflammatory and prothrombotic elements of cardiovascular disease (CVD) risk. Extremely high CRP levels are seen in acute inflammatory states, but the small elevations that are indicative of the pro-inflammatory and pro-thrombotic states implicated in the metabolic syndrome require high sensitivity assays and are thus referred to as hs-CRP levels. Levels below 3.0 mg/L are considered to be normal; 3.1—10 mg/L is elevated, in the context of CVD risk, and above 10 mg/ L is very high, more likely indicating an acute inflammatory event due to infection or trauma.
Triglycerides (TG): Triglycerides enter the circulation as the end-product of digesting dietary fat, and they are also synthesized by the liver. They are an important energy source for the body and are stored in fat cells. Elevated blood levels, or hypertriglyceridemia, often found in untreated diabetes and obesity, are an established indicator of atherogenic dyslipidemia. The National Cholesterol Education Program defines fasting triglyceride levels of 150 mg/dL or above as one of the diagnostic criteria for metabolic syndrome, although some studies have shown that fasting levels lower than 100 mg/dL should be considered as a more optimal cutoff in coronary heart disease risk assessment. The inflammatory state leading to the development of atherosclerosis may be triggered by “postprandial dysmetabolism,” a condition characterized by unusually high levels of glucose and triglycerides after a meal. Postprandial hypertriglyceridemia indicates the presence of remnant lipoproteins, which are believed to promote atherosclerosis, and it is also linked with insulin resistance and obesity. Several studies have found that triglyceride levels measured 2-4 hours after a meal are highly predictive of cardiovascular events, especially in women. Nonfasting levels >200 mg/dL are suggestive of postprandial dysmetabolism.
HDL Cholesterol (HDL): Cholesterol bound to high-density lipoprotein (HDL) in the blood is known as HDL cholesterol. A low level of circulating HDL cholesterol is one of the established criteria for the diagnosis of metabolic syndrome and has long been regarded as a powerful predictor of cardiovascular disease in both diabetics and non-diabetics. In a large cohort from the Framingham Study, a high total cholesterol/HDL cholesterol or LDL cholesterol/HDL cholesterol ratio was associated with increased coronary heart disease risk, and a high HDL cholesterol level was associated with reduced risk, in both men and women. Currently, the LDL cholesterol/HDL cholesterol ratio is regarded as a reliable tool for the evaluation of cardiovascular disease risk. While absolute values of each are still considered by the National Cholesterol Education Program (NCEP) as the optimal diagnostic indicators, the ratios that are currently accepted by doctors and researchers are as follows: total cholesterol:HDL cholesterol ratio – optimally below 4; LDL cholesterol:HDL cholesterol ratio – optimally below 3. The current NCEP recommendation to reduce the risk of cardiovascular disease is to maintain an HDL cholesterol level >40 mg/dL in both men and women.Hemoglobin A1c (HbA1c): Hemoglobin A1c (HbA1c) is a glycated form of haemoglobin that results from the binding of haemoglobin in red blood cells to glucose in the bloodstream. Once the haemoglobin has bound to glucose, it remains glycated. Circulating red blood cells have a lifespan of 120 days, therefore the amount of HbA1c at any time point reflects the average exposure of red blood cells to glucose over the previous 3 months. It can therefore indicate impaired glucose tolerance even when occasional fasting plasma glucose measurements are normal.
In women, controlled by a negative feedback loop involving several ovarian hormones, gonadotropin-releasing hormone (GnRH) is secreted in pulses from the hypothalamus, which stimulates LH production from the pituitary gland. In a normal menstrual cycle, a surge of LH production lasting around 48 hours occurs at the end of the follicular phase. This sudden burst of LH causes luteinization of the ovarian follicles and triggers ovulation.
In men, LH acts on the Leydig cells of the testes to stimulate the production of testosterone, which is necessary for sexual function as well as spermatogenesis. LH levels are useful for the clinical assessment of infertility: low levels in men can result in hypogonadism and insufficient sperm production, while in women LH levels are used to determine the occurrence of ovulation for couples trying to conceive. High LH levels are seen in polycystic ovarian syndrome, and in precocious puberty, levels are similar to those seen in reproductive age individuals instead of the lower levels normally seen in children.
LH levels can also be used in the diagnosis of pathologies of the hypothalamus or pituitary. As women enter menopause, LH levels rise as ovarian hormone production declines, reducing the negative feedback effect on GnRH production. LH testing can help evaluate a woman’s menopausal status. Ranges for blood spot LH in premenopausal women (luteal phase) are 0.5—12.8 U/ L, in premenopausal women (follicular phase) 1.6—9.3 U/L, in postmenopausal women 15—64 U/L, and in men 1.0—8.4 U/L