Test ID: B-242 | At-Home Blood Spot | Results in 3–5 Working Days
Could a Hormone Imbalance Be Behind Your Symptoms?
Female hormonal health is rarely a single-hormone issue — oestrogen, progesterone, testosterone, cortisol, DHEA-S, and SHBG all interact in a complex system. When one is off, the whole system is affected. If you recognise any of the following, this comprehensive panel could reveal the root cause:
- Hot flushes or night sweats
- Irregular, heavy, or painful periods
- Persistent fatigue or low energy
- Low libido or vaginal dryness
- Mood swings, anxiety, or depression
- Brain fog, poor concentration, or memory lapses
- Sleep disturbances or insomnia
- Unexplained weight gain or difficulty losing weight
- Bloating or PMS symptoms
- Fertility concerns or irregular ovulation
- Headaches, dizziness, or burnout
- Decreased stamina or mental fatigue
What This Test Measures
This panel tests eight essential hormones using highly accurate LC-MS/MS technology:
- Estrone (E1) – A post-menopausal oestrogen; elevated levels may indicate oestrogen dominance
- Estradiol (E2) – The primary reproductive oestrogen; key for cycle regulation, bone density, and mood
- Estriol (E3) – A weaker oestrogen that helps assess overall oestrogen balance, especially during perimenopause
- Progesterone (Pg) – Essential for cycle balance, fertility, and counteracting oestrogen dominance
- Testosterone (T) – Important for libido, energy, and muscle tone in women
- DHEA-S (DS) – An adrenal hormone that declines with age; linked to vitality, mood, and immune function
- Cortisol (C) – The stress hormone; chronically elevated cortisol disrupts oestrogen and progesterone balance
- SHBG (Sex Hormone Binding Globulin) – Determines how much oestrogen and testosterone is biologically available to your tissues
Why a Comprehensive Panel Matters
Hormonal imbalance in women is frequently misdiagnosed or dismissed. Symptoms like fatigue, low mood, weight gain, and irregular cycles are often attributed to stress or lifestyle — when the root cause may be hormonal. A single hormone test rarely tells the full story. This panel gives you a complete picture, enabling more informed conversations with your GP or specialist.
How It Works
- Order your kit — delivered to your door
- Collect your sample at home — a simple finger-prick blood spot; no clinic or GP visit needed
- Post your sample to our CLIA-certified laboratory using the instructions provided
- Receive your results by email within 3–5 working days of the lab receiving your sample
What You Get With Your Results
Your personalised report includes:
- All eight hormone levels displayed clearly in graphics and numbers
- A written interpretation by a Hormone Specialist PhD Doctor
- Guidance on what your results mean and what to do next
View a Sample Test Result Report
Who Is This Test For?
This test is suitable for women who want to:
- Investigate symptoms of perimenopause, menopause, PMS, or hormonal imbalance
- Understand why they feel unwell despite normal standard blood tests
- Assess fertility-related hormones alongside stress and adrenal markers
- Monitor hormone levels during or after HRT or other hormone therapy
- Take a proactive, data-driven approach to their hormonal health
Key Information
- Collect your sample from home and post to our lab — no clinic visit required
- Results delivered by email within 3–5 working days
- Laboratory fee included — no hidden costs or additional charges
- Valid for 12 months from the date of purchase
- Analysed by a CLIA-certified laboratory using LC-MS/MS technology with over 11 million tests performed
- Customers are responsible for posting their sample to the laboratory
Why We Use ZRT Laboratory
All testing is performed by ZRT Laboratory — a globally recognised, CLIA-certified diagnostic laboratory founded in 1998 by Dr. David Zava, PhD. ZRT has performed over 11 million tests and is trusted by healthcare professionals in 96+ countries.
- Pioneers of at-home dried blood spot (DBS) hormone testing
- Advanced LC-MS/MS and ICP-MS technology for clinical-grade accuracy
- Qualified for the CDC Hormone Standardization (HoSt) Program for testosterone and estradiol
- Personalised reference ranges based on age and sex
Through our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to women across the UK and Europe — from the comfort of home.
Frequently Asked Questions
What hormones does the Female Comprehensive Hormone Profile I test?
This panel measures eight hormones from a single blood spot sample: Estrone (E1), Estradiol (E2), Estriol (E3), Progesterone, Testosterone, DHEA-S, Cortisol, and SHBG. Together, these markers provide a complete picture of oestrogen balance, adrenal function, and how much active hormone your body is actually using.
Can I do this test at home without visiting a clinic or GP?
Yes. The kit is delivered to your door and uses a simple finger-prick blood spot — no venipuncture, no clinic visit, and no GP referral needed. You collect the sample yourself following the included instructions, then post it to our CLIA-certified laboratory in the prepaid envelope provided.
When is the best time to take this hormone test?
For women with a regular menstrual cycle, collecting your sample on days 19–21 of your cycle (counting from the first day of your period) is recommended, as this captures the mid-luteal peak when progesterone levels are most informative. For post-menopausal women or those with irregular cycles, the test can be collected at any time. Detailed timing guidance is included in your kit.
How accurate is this test compared to a standard NHS blood test?
This test uses LC-MS/MS (liquid chromatography-tandem mass spectrometry) — the same gold-standard technology used in specialist hospital laboratories. It is more sensitive and specific than the immunoassay methods typically used in NHS routine testing, particularly for measuring oestrogen fractions and testosterone in women at low concentrations.
What does it mean if my oestrogen is high but my progesterone is low?
This pattern — often called oestrogen dominance — is one of the most common hormonal imbalances in women. It can cause symptoms including heavy or irregular periods, bloating, breast tenderness, mood swings, and weight gain around the hips. Your results report will include a written interpretation from a PhD hormone specialist explaining what your specific levels mean and what steps to consider.
How long does it take to get results?
Results are delivered by email within 3–5 working days of the laboratory receiving your sample. You will receive a PDF report with all hormone levels, reference ranges, and a personalised written commentary from a hormone specialist.
Is this test suitable for women on HRT or the contraceptive pill?
Yes — monitoring hormone levels during HRT is one of the most common uses for this panel. If you are on HRT, the results can help confirm whether your current dosage is achieving optimal hormone levels. If you are on the combined contraceptive pill, note that synthetic hormones can suppress natural oestrogen and progesterone production, which will be reflected in your results.
What is SHBG and why does it matter?
SHBG (Sex Hormone Binding Globulin) is a protein that binds to oestrogen and testosterone, making them unavailable for use by your cells. High SHBG can mean that even if your total hormone levels appear normal, your body cannot use them effectively — leading to symptoms like low libido, fatigue, and mood changes. This test measures SHBG alongside your sex hormones so you get a true picture of hormonal availability, not just total levels.
