Weight Management

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Weight gain is often driven by more than diet and exercise — hormonal imbalances can significantly impact your ability to lose or maintain weight. Hormones regulate metabolism, blood sugar, insulin, and fat storage, so when they are out of balance, unexplained weight gain can occur. Our at-home weight management hormone test kits are analysed by PhD-level scientists using LC-MS/MS and ICP-MS methodology, with results returned within 3–5 working days.

Common hormonal contributors to weight gain include:

Estrogen & Progesterone Imbalance
Estrogen dominance promotes fat storage, particularly around the hips and thighs. Low progesterone can worsen fluid retention and bloating.

Low Testosterone or DHEA
Reduced anabolic hormones lead to decreased muscle mass and a slower metabolism, making weight management harder.

High or Low Cortisol
Chronic stress elevates cortisol, driving belly fat accumulation and sugar cravings. Low cortisol impairs energy and metabolic recovery.

Thyroid Dysfunction
An underactive thyroid (hypothyroidism) slows metabolism, causing weight gain, fatigue, and cold sensitivity even with normal diet and exercise.

Insulin Resistance & Elevated HbA1c
When cells become resistant to insulin, blood sugar rises and fat storage increases — a key driver of metabolic weight gain and type 2 diabetes risk.

Vitamin D Deficiency
Low vitamin D is associated with increased fat storage, reduced insulin sensitivity, and impaired metabolic function.

What does a weight management hormone test measure?

Saliva — Sex Hormones (LC-MS/MS): Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEAS.
Saliva — 4-Point Cortisol Profile: Morning, Noon, Evening, and Night Cortisol.
Blood Spot — Full Thyroid Panel: TSH, Free T3, Free T4, Total T4, TPO Antibodies, Thyroglobulin Antibodies.
Blood Spot — CardioMetabolic Panel: Fasting Insulin, HbA1c, HDL Cholesterol, Triglycerides, Total Cholesterol, hsCRP.
Blood Spot — Vitamin D: 25-OH Vitamin D2, 25-OH Vitamin D3.
26 markers total — the most comprehensive weight-focused at-home male and female health profile available in the worldwide, covering sex hormone balance, the full daily cortisol rhythm, autoimmune thyroid function, cardiometabolic risk, and Vitamin D status in a single kit.

Who should take a weight management hormone test?
These tests are suitable for adults experiencing unexplained weight gain, difficulty losing weight despite diet and exercise, fatigue, sugar cravings, belly fat accumulation, or those with suspected insulin resistance, thyroid dysfunction, or metabolic imbalance.