Neurotransmitters Advanced Test + Add On Saliva Hormone Test

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Neurotransmitters Advanced Profile in dried urine + Add on Saliva Hormone Test in saliva containing 30 tests below:

Neurotransmitters Advanced Profile Tests: 

  • Gamma-aminobutyric acid (GABA),
  • Glutamate (Glu),
  • Glycine (Gly),
  • Dopamine (DA),
  • Epinephrine (Epi),
  • Norepinephrine (NE),
  • Histamine (HIST), 
  • Serotonin (5-hydroxytryptophan (5-HT),
  • Phenethylamine (PEA), 
  • Dopamine metabolites (DOPAC),
  • Homovanillic acid (HVA),
  • 5-hydroxy indole 3-acetic acid (5-HIAA),
  • Normetanephrine (NMN),
  • Vanillylmandelic acid (VMA),
  • Creatinine (Crtn),
  • Tryptophan,
  • Kynurenic acid,
  • 3-Hydroxykynurenine,
  • Xanthurenic acid,
  • Taurine,
  • Glutamine,
  • Histidine,
  • N-Methylhistamine,
  • Tyrosine,
  • Tyramine.

Add On Saliva Hormone Test Profile: 

  • Estradiol (E2),
  • Progesterone (Pg),
  • Testosterone (T),
  • DHEAS (DS), and
  • Cortisol (C) in saliva.

Test Result: You will receive your test result 3-5 working days after the laboratory receives your sample. You will see your hormone levels in graphics and numbers on your test result. You will also see laboratory comments by Hormone Specialist PhD Dr in the comments: you will find Dr analysis of your hormone levels and what to do next. 

Neurotransmitters are chemical messengers the nervous system uses to relay information from one nerve to another.

Optimal neurotransmitter balance is required to maintain proper health. Imbalances can cause the brain and the body to be over-or under-stimulated, producing neurological or psychological symptoms.

    NEUROTRANSMITTERS PLAY A KEY ROLE in mental conditions, such as depression & anxiety, which can occur when neurotransmitter levels are out of balance.

    NEUROTRANSMITTERS & YOUR HEALTH

    • Do you suffer from anxiety or depression? 
    • Do you struggle to fall asleep or stay asleep throughout the night? 
    • Men, has your libido fizzled?
    • Women, do you dread the weeks before your period?

    If you answered yes to these questions, an underlying neurotransmitter imbalance might be the cause. Simple testing may help you find personalized solutions.

    Neurotransmitters & Their Impact:

    Neurotransmitters are chemical messengers the nervous system uses to relay information from one nerve to another.

    The body relays information through the nervous system about anything it experiences, hears, touches, smells, or ingests – continuously communicating back and forth between the brain and the body.

    Optimal neurotransmitter balance is required to maintain proper health. Imbalances can cause the brain and the body to be over-or understimulated, producing neurological or psychological symptoms. 

    Can a Dysregulated Nervous System Impact Health?

    Like hormones, neurotransmitters require a delicate balance to keep the body functioning at a peak level.

    Genetics, environment, chemicals, and nutritional deficiencies are a few factors that can result in over-or under-production of neurotransmitters. Once out of balance, the nervous system begins to compensate – which, in time, can lead to neurological or psychological symptoms.

    Some more common psychological conditions today are known to be accompanied by neurotransmitter imbalances. However, it's also possible for individuals to present with similar symptoms yet have unique foundational imbalances. Testing helps clarify these root issues.

    Symptoms:

    If you regularly suffer from 3 or more of these symptoms, you might have a neurotransmitter imbalance.

    • ADD/ADHD
    • Aggression
    • Anxiety
    • Fatigue
    • Forgetfulness
    • Hyperactivity
    • Impulsive behaviours
    • Insomnia
    • Low libido
    • Mood swings
    • Obsessive-compulsive disorder (OCD)
    • Panic attacks
    • Poor concentration
    • Pre-menstrual dysphoric disorder (PMDD)
    • Severe PMS
    • Sleeping problems

    Neurotransmitters You Should Know

    There are many neurotransmitters in the body. The primary messengers are divided into two groups.

    Excitatory:

    • Dopamine, generally regarded as the brain's pleasure and reward centre, plays a central role in addiction, improves attention, focus and motivation, and modulates movement control.
    • Epinephrine and Norepinephrine regulate the "fight or flight" response, elevate blood pressure and heart rate, stimulate wakefulness and reduce digestive activity.
    • Glutamate functions as the "on" switch in the brain. The major excitatory neurotransmitter decreases sleep, optimizes learning, memory, and mood, and improves libido.
    • Histamine plays a role in the body as a neurotransmitter that increases metabolism, promotes wakefulness, and suppresses appetite.
    • PEA (phenylethylamine) promotes energy, elevates mood, regulates attention and aggression, and is a biomarker for ADHD.

    Inhibitory:

    • GABA functions as the "off" switch in the brain. The major inhibitory neurotransmitter improves mood, relieves anxiety, and promotes sleep.
    • Glycine plays a dual role as a neurotransmitter and amino acid that serves as a building block to proteins, improves sleep quality, calms aggression, and serves as an anti-inflammatory agent.
    • Serotonin, generally regarded as the "happiness molecule," contributes to the feeling of calm and well-being that eases depression and anxiety, supports sleep, and decreases appetite.

    Neurotransmitter Imbalance & Chronic Conditions

    Numerous neurotransmitter imbalances may cause persistent health concerns:

    • Anxiety & Depression: Imbalances are often associated with Glutamate (panic attacks), PEA, Histamine, Serotonin, Epinephrine and Norepinephrine.
    • Fatigue: An imbalance between excitatory and inhibitory neurotransmitters is likely.
    • Impulsivity: GABA, Dopamine, and Serotonin are three chemical messengers commonly linked to disorders like ADD, ADHD, and OCD.
    • Insomnia: Glutamate, Histamine, Dopamine, GABA, and Serotonin are several chemical messengers often linked to sleep disturbances and insomnia.
    • PMS or PMDD: Imbalances such as Serotonin, Dopamine, Norepinephrine, and GABA are often involved

    Neurotransmitter Testing – Giving a Diagnostic Edge in Treating Mood Disorders.

    Mental health disorders affect millions of people and profoundly contribute to the disease burden in society.

    The current treatment paradigm in addressing poor brain health relies on diagnostic tools that encompass the evaluation of clinical signs and symptoms. Despite the lack of testable biomarkers for mood disorders, treatments can be effective for many patients. However, even after treatment, frequent relapse episodes can still occur. Furthermore, a large number of patients suffer from treatment-resistant depression. Therefore, selecting the best therapeutic regimen for each patient remains a challenge and is often discovered through a time-consuming process of trial and error. Also, no single approach works for everyone with any one disorder.

    Targeted neurotransmitter testing can help health care practitioners achieve a diagnostic edge beyond the traditional psychological inventory by identifying specific imbalances in neurotransmitter levels. Based on neurotransmitter test results, practitioners can identify specific biochemical heterogeneities for each patient and objectively monitor therapeutic responses during and after the intervention. Neurotransmitter testing objectively enhances medical assessment and represents a major advance in the personalization of the treatment of mood disorders.

    Clinical Utility of Urinary Neurotransmitter Analysis:

    The aetiology of mood disorders is profoundly complex and likely encompasses many different types of neurotransmitters, how they achieve balance in the brain and the gut axis, and how they each interplay with other hormone systems throughout the body. Appropriate balancing of neurotransmitter signals allows the body to maintain equilibrium. When the brain and peripheral neurochemistry become unbalanced, the body will struggle to re-establish physiological integrity, which may present in the form of suboptimal psychological well-being. Excessive or deficient levels of certain neurotransmitters in both the brain and in the periphery are associated with a spectrum of neurobiological disorders, such as depression and anxiety. The measurement of specific imbalances may be a very effective neurobiological tool in guiding targeted intervention aimed at addressing the individual excess or deficiency in question.

    Dried Urine – A Convenient Testing Option:

    The nature of urine collection is non-invasive and preferable to the traditional invasive collection approaches, such as the measurement of cerebrospinal fluid. However, even with liquid urine collection, the patient experiences the enormous hassle of collecting all urine voids over 24 hours into a large jug. To circumvent this inconvenience, some labs have settled for collecting only the 2nd void, limiting neurotransmitter results to a single morning time point snapshot. ZRT Laboratory offers an alternative to the liquid urine collection method by offering a simple and convenient collection of four separate urine samples at specific time points throughout the day – 1st morning, 2nd morning (approximately 2 hours after the first collection), early evening, and bedtime. Urine is collected onto filter strips by urinating directly on the strip or dipping the filter card in a cup containing the collected urine. The urine cards are then allowed to dry overnight and sent to ZRT for testing. The convenience of the collection method warrants patient compliance and ease of incorporation into clinical practice.

    Considerations:

    • The neurotransmitter test assumes proper kidney function. Neurotransmitter levels are reported in µg/g creatinine, where creatinine is measured from the same sample. This test should not be used in individuals with compromised renal function. 
    • The sample can dilute due to increased fluid consumption during the day. Therefore, individuals should restrict their liquid intake to normal consumption on testing.
    • On the day of testing, individuals are advised to refrain from consuming alcohol, nicotine, bananas, pineapple, and walnuts as they may interfere with testing.

    Male Estrogen/Progesterone Deficiency Symptoms:

    • Bone loss
    • Depression
    • Heart palpitations
    • Hot flushes
    • Neck or back pain
    • Nights sweats
    • Sleeping difficulties

    Male Estrogen Dominance/Progesterone Deficiency Symptoms:

    • Cold body temperature
    • Irritable
    • Low libido
    • Prostate problems
    • Increased urinary urge
    • Decreased urine flow
    • Breast or hips weight gain

    Male low Androgens (DHEA/Testosterone) deficiency symptoms:

    • Allergies
    • Apathy
    • Body temperature cold
    • Bone loss
    • Burned-out feeling
    • Depression
    • Decreased erections
    • Evening fatigue
    • Mental fatigue
    • Morning fatigue
    • Decreased flexibility
    • Forgetfulness
    • Headaches
    • Heart palpitations
    • Hot flushes
    • Irritability
    • Joint pain
    • Low libido
    • Decreased mental sharpness
    • Decreased muscle size
    • Muscle soreness
    • Night sweats
    • Rapid ageing
    • Ringing in ears
    • Skin thinning
    • Decreased stamina
    • Stress
    • Triglycerides elevated
    • Waist Weight gain

    Male low Cortisol deficiency symptoms:

    • Low blood pressure
    • Low blood sugar
    • Chemical sensitivity
    • Depression
    • Dizzy spells
    • Fatigue
    • Infertility
    • Irritability
    • Joint pain
    • Decreased mental sharpness
    • Slow pulse rate
    • Decreased stamina
    • Stress
    • Sugar cravings
    • Swelling or puffy eyes/face

    Male high Cortisol deficiency symptoms:

    • Anxious
    • High blood pressure
    • Depression
    • Forgetfulness
    • Hot flushes
    • Decreased mental sharpness
    • Decreased muscle size
    • Nervousness
    • Night sweats
    • Rapid ageing
    • Skin thinning
    • Sleeping difficulty
    • Stress
    • Sugar cravings
    • Triglycerides elevated
    • Waist weight gain

    If any symptoms mentioned above persist, you might consider using our comprehensive 10-panel hormone test. This test has clear instructions on how to use it safely and comfortably. In addition, saliva testing produces a non-invasive use as it does not require the use of any needle or instruments that other testing kits may provide.

    Female Estrogen/Progesterone deficiency symptoms:

    • Aches & pains
    • Acne
    • Bone loss
    • Depression
    • Foggy thinking
    • Increased facial or body hair
    • Heart palpitations
    • Hot flushes
    • Incontinence
    • Infertility
    • Memory lapse
    • Night sweats
    • Rapid ageing
    • Rapid heartbeat
    • Skin thinning
    • Sleep disturbance
    • Tearfulness
    • Increased urinary urge
    • Vaginal dryness
    • Weight Gain-Waist

    Female Estrogen dominance/Progesterone deficiency symptoms:

    • Anxious
    • Bleeding changes
    • Cold body temperature
    • Breast cancer
    • Fibrocystic breasts
    • Tender breasts
    • Depression
    • Headaches
    • Infertility
    • Irritability
    • Mood swings
    • Nervousness
    • Uterine fibroids
    • Water retention
    • Hip weight gain

    Female low Androgens (DHEA/Testosterone) deficiency symptoms:

    • Aches & pains
    • Allergies
    • Bone loss
    • Depression
    • Morning/evening fatigue
    • Fibromyalgia
    • Headaches
    • Incontinence
    • Decreased libido
    • Memory lapse
    • Decreased muscle size
    • Rapid ageing
    • Skin thinning
    • Stamina decreased
    • Vaginal dryness

    Female high Androgens (DHEA/Testosterone) deficiency symptoms:

    • Acne
    • Breast cancer
    • Increased facial or body hair
    • Hair-scalp loss
    • Irritability
    • Triglycerides elevated
    • Waist weight gain

    Female low Cortisol deficiency symptoms:

    • Aches & pains
    • Allergies
    • Low blood pressure
    • Low blood sugar
    • Cold body temperature
    • Chemical sensitivity
    • Morning/evening fatigue
    • Fibromyalgia
    • Slow pulse rate
    • Decreased stamina
    • Stress
    • Sugar craving

    Female high Cortisol deficiency symptoms:

    • Anxious
    • High blood pressure
    • Bone loss
    • Breast cancer
    • Depression
    • Foggy thinking
    • Hot flushes
    • Infertility
    • Irritability
    • Memory lapse
    • Decreased muscle size
    • Nervous
    • Night sweats
    • Rapid ageing
    • Rapid heartbeat
    • Skin thinning
    • Sleep disturbance
    • Stress
    • Uterine fibroids
    • Waist weight gain.

    This test has clear instructions on how to use it safely and comfortably. 

    Saliva testing measures hormones like cortisol, estrogen, progesterone, DHEA and testosterone. Its non-invasive collection asks patients to spit into a plastic tube. This sampling method allows patients to collect saliva at home at specific times, which is vital for measuring hormone levels accurately.