Neurotransmitter and Cortisol Test | Specialist Interpretation Included

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Neurotransmitter and Cortisol Test

Test ID: SU-843

Saliva 4-Point Cortisol + Dried Urine LCMS Neurotransmitters Test is a comprehensive assessment combining 4-point salivary cortisol testing with LC-MS dried urine neurotransmitter analysis, designed to evaluate stress patterns and full-spectrum neurotransmitter metabolism.


What This Test Measures

Neurotransmitters Urine Markers – 26 Measurements

  • Tryptophan (Trp)
  • Serotonin (5-HT)
  • 5-Hydroxyindoleacetic Acid (5-HIAA)
  • Gamma-Aminobutyric Acid (GABA)
  • Glycine (Gly)
  • Taurine (Tau)
  • Glutamate (Glu)
  • Glutamine (Gln)
  • Histidine (His)
  • Histamine (HIST)
  • N-Methylhistamine (N-MeHist)
  • Phenylethylamine (PEA)
  • Tyrosine (Tyr)
  • Tyramine (Tyra)
  • Dopamine (DA)
  • 3,4-Dihydroxyphenylacetic Acid (DOPAC)
  • Homovanillic Acid (HVA)
  • Norepinephrine (NE)
  • Normetanephrine (NMN)
  • Epinephrine (Epi)
  • Vanillylmandelic Acid (VMA)
  • Kynurenine (Kyn)
  • Kynurenic Acid (KynAc)
  • 3-Hydroxykynurenine (3OHKyn)
  • Xanthurenate (Xanth)
  • Creatinine (Crtn)

Total Urine Measurements: 26

Cortisol Saliva – 4 Measurements

  • Morning Cortisol (C)
  • Noon Cortisol (C)
  • Evening Cortisol (C)
  • Bedtime Cortisol (C)

Total Saliva Measurements: 4

Total Measurements: 30 Tests


Why This Test Is Different

LC-MS Gold Standard Technology. Liquid Chromatography–Mass Spectrometry (LCMS) offers high sensitivity & specificity, extended linear range, and reliable detection of complex metabolic pathways.


Key Features

  • Comprehensive Evaluation: In-depth analysis of multiple neurotransmitters, providing a detailed overview of an individual’s neurochemical profile.
  • Objective Measurement: Quantitative, laboratory-based measurement of neurotransmitter levels, supporting clinical assessments with reliable and objective data.
  • Personalised Treatment Planning: By identifying specific imbalances, healthcare professionals can design tailored treatment strategies including targeted supplementation, medication support, nutritional adjustments, and lifestyle changes.
  • Diagnostic Support: Assists in the evaluation of various neurological and mental health conditions by providing objective biochemical insights.
  • Targeted Therapeutic Guidance: Results highlight specific deficiencies or excesses, allowing interventions to focus directly on restoring neurotransmitter balance.
  • Progress Monitoring: Testing can be repeated to track treatment effectiveness over time.
  • Suitable for All Ages: Appropriate for both adults and children.
  • Non-Invasive Home Collection: Simple at-home sampling using four dried urine strips collected throughout the day.
  • Free UK Delivery: Complimentary shipping of the test kit within the United Kingdom.
  • All-Inclusive Laboratory Fee: The test kit price includes the full laboratory analysis fee with no additional lab charges or taxes.
  • Advanced Report Access: Click to view the >> Advanced Neurotransmitter Test Report
  • Validity Period: The kit must be used within 12 months from the purchase date.
  • Fast Turnaround: Results delivered within 3–5 working days after the laboratory receives the sample.

Who Is This Test For?

You may benefit if you experience anxiety or depression, mood swings, insomnia or poor sleep, fatigue, ADHD / focus issues, panic attacks, PMS or PMDD, low libido, brain fog, impulsivity, or chronic stress. If you regularly experience 3 or more of these symptoms, neurotransmitter imbalance may be contributing.


Why Test Neurotransmitters?

Neurotransmitters regulate mood & emotional stability, sleep–wake cycles, motivation & reward pathways, memory & cognitive performance, pain perception, appetite regulation, and autonomic functions. Imbalances can contribute to anxiety, depression, ADHD, OCD, chronic fatigue, sleep disorders, PMS/PMDD, and treatment-resistant mood disorders.


Cortisol + Neurotransmitters: Why Combine Them?

Chronic stress alters neurotransmitter balance. 4-point cortisol testing helps assess morning activation, afternoon energy stability, evening wind-down, and overall HPA axis resilience. Combined testing provides a deeper understanding of stress-induced neurochemical changes, burnout patterns, and adrenal–neurotransmitter interactions.


How the Test Works

At-Home Collection

  • 4 saliva samples (specific times)
  • 4 dried urine strips throughout the day
  • Simple instructions included

Your Report Includes

  • Graphical and numerical results
  • Interpretation comments from Specialist PhD Dr.
  • Clinical guidance suggestions
  • Clear explanation of imbalances
  • Click to view the >> Advanced Neurotransmitter Test Report

Test Kit Includes

  • Test requisition form with symptom checklist
  • Medical history form
  • Detailed collection instructions
  • Dried urine collection cards
  • Saliva collection materials
  • Return envelope
  • Shipping instructions

The test must be used within 12 months of purchase.


Important Considerations

  • Assumes normal kidney function
  • Not suitable for individuals with compromised renal function
  • On test day: avoid alcohol, nicotine, bananas, pineapple, walnuts
  • Maintain normal fluid intake (avoid excessive drinking)
  • Detailed sample collection instructions provided with the test kit

Free UK Delivery | Laboratory Fee Included | No Additional Costs

Take control of your neurochemistry with advanced, clinically validated testing.