Blog

Navigating the Neurochemical Landscape: Understanding the Interplay of Stress, Neurotransmitters, and HPA Axis Dysfunction

Posted by Behcet Bicakci on

A complex interplay of neurochemical signals takes centre stage when it comes to stress and the body's response to it. Translating events into neurochemical signals is crucial before triggering the HPA (hypothalamic-pituitary-adrenal) axis, which plays a pivotal role in the body's stress response. In this blog post, we'll explore the intricate connections between neurotransmitters, stress, and HPA axis dysfunction, shedding light on clinicians' challenges when evaluating patients. The Prevalence of Anxiety & Depression: Anxiety disorders and major depressive disorder (MDD) are pervasive mental health challenges affecting millions. Abnormal neurotransmitter levels, ratios, or activities are often associated with these disorders, leading...

Read more →


Understanding and Managing Acne: A Comprehensive Guide Part 5 Complications

Posted by Behcet Bicakci on

  Acne, a prevalent skin condition affecting millions worldwide, is often perceived as a transient issue associated with adolescence. However, the aftermath of persistent or severe acne can leave enduring reminders in the form of scarring and emotional distress. These complications, though distinct, intertwine to influence an individual's perception of self and overall well-being. When acne lesions, particularly nodules and cysts, burst or are subjected to picking or squeezing, they can lead to scarring. The resulting scars manifest in various forms: ice pick scars, resembling punctured holes; rolling scars, causing uneven skin texture; and boxcar scars, forming depressions or craters....

Read more →


Understanding and Managing Acne: A Comprehensive Guide Part 4 Treatment

Posted by Behcet Bicakci on

Acne, a common skin condition affecting people worldwide, often requires tailored treatment based on its severity. Various treatment options, from over-the-counter remedies to prescription medications, cater to different forms and stages of acne. Understanding these treatment methods is vital for effective management and clearer skin.  Over-the-Counter Solutions: For Mild Acne: Initial episodes of acne, characterised by a few blackheads, whiteheads, and spots, can often be managed with guidance from pharmacists. Over-the-counter gels or creams containing benzoyl peroxide are recommended for their antibacterial and anti-inflammatory properties. Prescription Medications: Moderate to Severe Acne: If acne persists or worsens despite over-the-counter treatments, seeking...

Read more →


Understanding and Managing Acne: A Comprehensive Guide Part 3 Diagnosis

Posted by Behcet Bicakci on

Diagnosing acne goes beyond a mere visual examination, determining its severity and potential underlying causes. This comprehensive evaluation by a medical professional helps tailor appropriate treatments to alleviate symptoms effectively.  Diagnostic Process: A General Practitioner (GP) conducts a thorough examination, observing the affected areas like the face, chest, or back to identify distinctive acne symptoms. The presence of blackheads, red nodules, or sore spots assists in categorizing acne severity. Assessing Acne Severity: The severity of acne typically falls into three categories, guiding the course of treatment: Mild Acne: Predominantly characterized by whiteheads and blackheads, occasionally accompanied by a few papules...

Read more →


Understanding and Managing Acne: A Comprehensive Guide Part 2 Causes

Posted by Behcet Bicakci on

Acne, a pervasive skin condition, arises when hair follicles—tiny skin holes—become obstructed. Understanding the intricate mechanisms behind this condition unveils the complex interplay of hormones, genetics, and lifestyle factors.  The Role of Sebaceous Glands: Sebaceous glands near the skin surface produce sebum, an oily substance that moisturises hair and skin. However, these glands begin overproducing sebum in acne, combining it with dead skin cells to create a plug within the follicle. This plug's emergence on the skin's surface leads to either a whitehead or blackhead. Bacterial Infection and Inflammation: When plugged, follicles encounter bacteria that usually reside harmlessly on the...

Read more →