Blog — HPA Axis

Neurotransmitters, Mood & the Perception of Stress

Posted by Ben White on

When we talk about “stress,” or allostatic load, in terms of the perception of an event, we must realize that these “events” must first be translated into neurochemical signals before they trigger the HPA axis. Therefore, the sensitivity and outcome of translating these events (whether they are ongoing events, memories of past events, or stressful anticipation of unrealized events), is highly dependent upon signaling from other neurotransmitters. In fact, the signaling neurotransmitters that manage mood and affect often overlap with measures of HPA axis activation, and cannot be easily distinguished in some subjects. [1] While the detailed influence of neurotransmitters, such...

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Diurnal Fluctuations in Norepinephrine and Epinephrine Levels as Part of the Healthy Stress Response

Posted by Ben White on

Original of this article was published on ZRT Laboratory website. Posted by Dr. Kate Placzek Stress has become a synonymous, integral even, accompaniment of life in our fast-paced world. Generally regarded as "distress," our bodies struggle to re-establish physiological integrity at certain times, such as after working long hours, or when we have insufficient exercise, sleep and nutrition. Driven by persistent exposure to stressors, the body begins to lose its dynamic resilience and fails to return the system to a normal baseline healthy state. Derailed and overwhelmed, our susceptibility to stress-related diseases is greatly increased. The Building Blocks of the...

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