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The Progesterone / Estradiol (Pg/E2) Ratio

Posted by Ben White on

The Progesterone / Estradiol (Pg/E2) Ratio

When sex hormones are tested in women either in saliva or blood spot, ZRT test reports give a ratio of progesterone (Pg) to estradiol (E2). The ratio is helpful in clinical practice when both E2 and Pg are within range, yet the patient continues to have symptoms. It is not expected to be normal or used clinically when either E2 and/or Pg are outside of their expected ranges or if the patient does not have clinical symptoms. A low ratio occurs when Pg is low relative to E2. This describes the classic situation of estrogen dominance.  In general, either decreasing estrogen and/or increasing progesterone...

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