Blog – Tagged "Early Menobapuse" – Hormone Lab UK

Blog — Early Menobapuse

Trials of HRT Started in Early Menopause - Research Updates

Posted by Ben White on

Trials of HRT Started in Early Menopause - Research Updates

One of the primary objectives of the Women's Health Initiative was to see if postmenopausal hormone replacement therapy (HRT) improved long-term risk of coronary heart disease, among other chronic diseases. However, the combined estrogen/progestin (Prempro) arm was halted in 2002, citing that the participants’ risk of cardiovascular disease outweighed any potential benefit of HRT in the prevention of colorectal cancer and bone fracture [1]. The conjugated equine estrogen (CEE)-only arm was also halted in 2004 citing no improvement in heart disease risk but an increased incidence of stroke, and no benefit in terms of fractures, although there was a reduced breast...

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