Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — PCOS and insulin resistance

Hormonal acne is one of the most common and frustrating skin conditions affecting women across all life stages — from puberty and perimenopause to post-pill breakouts and PCOS. At its root, acne is an inflammatory condition driven by androgen excess, sebum overproduction, skin microbiome disruption, and immune activation. Diet, gut health, and hormonal imbalances all play interconnected roles. This article explains the science behind hormonal acne, the key hormones involved, the role of diet and the microbiome, and how targeted hormone testing can identify the specific drivers of your breakouts.

When a patient with PCOS or weight issues is told “your blood sugar is normal,” the story is far from over. In this clinical article, Dr. Alison McAllister of ZRT Laboratory explains why insulin — not glucose — is the primary driver of PCOS symptoms, weight gain, testosterone and DHEAS excess, and cortisol dysfunction. Understanding the progression from insulin resistance to hyperinsulinemia to type 2 diabetes is essential for identifying and treating PCOS at the earliest possible stage.