Test ID: SU-840
Test Numbers: 33 Markers
Sample types: Saliva and dried urine
Laboratory method: Advanced LC-MS/MS analysis
Profile: 7 saliva hormones plus 26 dried-urine neurotransmitter markers
Laboratory: ZRT Laboratory
Results: Usually emailed within 3–5 working days after the laboratory receives your samples
A comprehensive view of hormones and neurotransmitter pathways
The SU-840 Neurotransmitter & Hormone Test combines a seven-hormone saliva profile with an extensive dried-urine neurotransmitter panel. It is designed for people who want to explore how hormone status and systemic neurotransmitter pathways may relate to symptoms involving mood, stress, sleep, energy, concentration, menstrual health or libido.
The saliva profile measures oestrogens, progesterone, testosterone, DHEA-S and cortisol. The dried-urine profile measures serotonin, dopamine, GABA, glutamate, norepinephrine and other neurotransmitters together with important precursors and metabolites.
Looking at both systems in one profile may provide more useful context than testing either hormones or neurotransmitters alone. Your personalised laboratory report can help you and your healthcare professional identify patterns that may warrant further assessment or appropriately targeted support.
Important: Urinary neurotransmitter testing measures neurotransmitters, precursors and metabolites excreted in urine. It does not directly measure neurotransmitter activity in the brain. This test cannot diagnose a hormonal, mental health, neurological or sleep condition.
Could this test be relevant to your symptoms?
You may wish to discuss this combined profile with a qualified healthcare professional if you have ongoing or unexplained symptoms such as:
- Persistent tiredness or fluctuating energy
- Low mood, irritability or frequent mood changes
- Feeling anxious, tense, overwhelmed or unable to switch off
- Poor concentration, forgetfulness or mental fog
- Difficulty falling asleep, staying asleep or waking refreshed
- Reduced motivation or enjoyment
- Low libido or changes in sexual wellbeing
- Menstrual changes, PMS or premenstrual mood symptoms
- Hot flushes, night sweats or vaginal dryness
- Changes in weight or body composition
- Reduced strength, stamina or muscle mass
- Difficulty coping with everyday stress
These symptoms are not specific to neurotransmitter or hormone imbalance. They can have many possible causes, including medical conditions, medicines, nutrition, lifestyle, psychological wellbeing and sleep disorders. Testing should be used as part of a wider assessment rather than as a stand-alone explanation.
How may the SU-840 test help?
This combined profile may help you better understand:
Sex-hormone patterns: Saliva measurements provide information about estradiol, estriol, estrone, progesterone and testosterone.
Adrenal-related hormones: DHEA-S and cortisol add context about androgen status and the body’s stress-response system.
Neurotransmitter pathways: The urine profile measures key markers across serotonin, dopamine/catecholamine, GABA/glutamate, histamine and kynurenine pathways.
Overlapping symptoms: Hormonal changes and neurotransmitter pathways can both be relevant to mood, sleep, cognition, stress resilience and libido.
Possible next steps: A practitioner can interpret the findings alongside symptoms, medical history, medicines and other investigations to decide whether further assessment is appropriate.
The report is not a prescription. Do not start supplements, stop medicines or change treatment solely on the basis of these results.
What does the test measure?
The SU-840 profile includes 33 markers in total.
Saliva hormone profile – 7 markers
| Hormone group | Markers included |
|---|---|
| Oestrogens | Estradiol (E2), estriol (E3), estrone (E1) |
| Progesterone | Progesterone (Pg) |
| Androgens | Testosterone (T), dehydroepiandrosterone sulphate (DHEA-S / DS) |
| Stress hormone | Cortisol (C) |
Dried-urine neurotransmitter profile – 26 markers
| Pathway or group | Markers included |
| Serotonin and tryptophan | Tryptophan (Trp), serotonin (5-HT), 5-hydroxyindoleacetic acid (5-HIAA) |
| GABA, glutamate and related amino acids | Gamma-aminobutyric acid (GABA), glycine (Gly), taurine (Tau), glutamate (Glu), glutamine (Gln) |
| Histamine | Histidine (His), histamine (HIST), N-methylhistamine (N-MeHist) |
| Phenylethylamine | Phenylethylamine (PEA) |
| Dopamine and catecholamines | Tyrosine (Tyr), tyramine (Tyra), dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), norepinephrine (NE), normetanephrine (NMN), epinephrine (Epi), vanillylmandelic acid (VMA) |
| Kynurenine pathway | Kynurenine (Kyn), kynurenic acid (KynAc), 3-hydroxykynurenine (3OHKyn), xanthurenate (Xanth) |
| Sample correction | Creatinine (Crtn) |
Why test hormones and neurotransmitters together?
Hormones and neurotransmitter systems are biologically connected, although their relationships are complex and cannot be reduced to a single “high” or “low” result.
- Oestrogens interact with pathways involved in serotonin and other chemical messengers.
- Progesterone and its metabolites interact with signalling related to GABA.
- Testosterone and DHEA-S may be relevant to energy, motivation, body composition and sexual wellbeing.
- Cortisol is part of the stress-response system and may overlap with symptoms involving sleep, mood and energy.
- Neurotransmitter precursors and metabolites provide information about production, metabolism and excretion across several systemic pathways.
Combining these measurements may help a practitioner consider whether symptoms are occurring alongside identifiable hormone or urinary neurotransmitter patterns. It does not prove that a particular result caused a symptom.
Key benefits of the SU-840 home test
- Two complementary profiles in one test kit
- 33 hormone and neurotransmitter markers
- Advanced LC-MS/MS laboratory analysis
- Convenient, non-invasive saliva and dried-urine collection at home
- No blood draw or clinic appointment required
- Includes neurotransmitter precursors and metabolites, not only end markers
- Creatinine-corrected urinary reporting
- Personalised report with numerical results, graphs and laboratory comments
- Laboratory analysis included in the purchase price
- Free test-kit delivery within the UK
- Suitable for adults; use for a child should be agreed with the child’s healthcare professional
How home collection works
The kit contains the materials needed to collect saliva and dried urine at home. Collect each sample at the time specified in the enclosed instructions, allow the urine cards to dry fully and return all required samples with the completed requisition form.
Collection timing may depend on your sex, menstrual status, menstrual cycle, hormone use and the markers being assessed. Following the kit instructions closely is essential for interpretable results.
What is included in the test kit?
- Saliva collection tube or tubes
- Dried-urine collection cards
- Test requisition form and symptom checklist
- Personal and medical history section
- Step-by-step collection instructions
- Return envelope
- Shipping guidance
- Laboratory analysis and personalised report
Customers are responsible for the cost of returning samples to the laboratory. The kit should be used within 12 months of purchase.
Preparing for your test
Medicines, hormone therapy, supplements, food, drink, nicotine, exercise and collection timing may influence results. Follow the instructions supplied with the kit and record all medicines, hormones and supplements on the requisition form.
Do not stop prescribed medication or hormone therapy unless your prescribing clinician specifically advises you to do so. If you menstruate, the ideal collection day may depend on your cycle and the clinical question. If you are unsure when to collect, contact us or speak to your healthcare professional before taking the samples.
Urinary neurotransmitter results assume normal kidney function. This part of the test may not be suitable for people with impaired renal function. If you are pregnant, breastfeeding, under 18, have kidney disease, have a diagnosed endocrine, mental health or neurological condition, or are receiving treatment, obtain professional advice before ordering.
Your personalised results
Results are usually emailed within 3–5 working days after ZRT Laboratory receives all required samples. The report presents measurements in numerical and graphical form, with laboratory reference ranges and specialist comments where applicable.
Reviewing the report with a qualified healthcare professional is recommended. They can interpret the results in the context of your symptoms, age, sex, menstrual or menopausal status, medical history, medicines and other investigations.
Frequently asked questions
What is the SU-840 Neurotransmitter & Hormone Test?
SU-840 is a combined home test measuring seven hormones in saliva and 26 neurotransmitter-related markers in dried urine. It is intended to provide additional information about hormone status and systemic neurotransmitter pathways.
Who may consider this combined profile?
It may be considered by adults experiencing persistent symptoms involving mood, energy, concentration, stress, sleep, menstrual wellbeing, menopausal changes or libido. Because these symptoms have many possible causes, professional assessment remains important.
Does the urine test measure neurotransmitters in the brain?
No. Urinary measurements are not a direct reading of neurotransmitter activity in the brain. They reflect neurotransmitters, precursors and metabolites excreted by the body and should be interpreted as part of a wider clinical picture.
Can the test diagnose anxiety, depression, ADHD or another condition?
No. It cannot diagnose anxiety, depression, ADHD, autism, OCD, bipolar disorder, insomnia or any other medical or psychiatric condition. Diagnosis requires an appropriate assessment by a qualified healthcare professional.
Can this test diagnose menopause, infertility or a hormone disorder?
No. Hormone results may provide useful additional information, but diagnosis depends on your symptoms, history and—where appropriate—other clinical tests. Consult your GP or specialist about irregular bleeding, fertility concerns or significant menopausal symptoms.
Why use saliva for hormone testing?
Saliva collection is non-invasive and convenient at home. It measures the unbound fraction of selected steroid hormones present in saliva. Correct timing and careful collection are important.
Why use dried urine for neurotransmitter testing?
Dried urine collection is convenient, stable for transport and avoids a 24-hour collection jug. Urinary testing provides information about systemic neurotransmitter production, metabolism and excretion.
Why is creatinine included?
Urine concentration varies with hydration and other factors. Creatinine allows the laboratory to report neurotransmitter markers relative to sample concentration.
Can I take my normal medication and supplements?
Some medicines, hormones and supplements can affect results. Follow the instructions, declare everything you take and seek advice if you are unsure. Never stop prescribed treatment without consulting the prescribing clinician.
Is the test suitable for children?
The collection methods may be used for children, but suitability should be discussed with a paediatrician or another appropriately qualified healthcare professional. It does not replace developmental, behavioural, endocrine or mental health assessment.
How long do results take?
Results are normally emailed within 3–5 working days after the laboratory receives all samples. Delivery and return-shipping time are not included.
Are laboratory fees included?
Yes. The price includes the collection kit, laboratory analysis and report. The customer pays the cost of returning samples to the laboratory.
What should I do with my results?
Discuss them with a qualified healthcare professional, particularly if symptoms persist or results are outside the stated reference ranges. Your practitioner can determine whether further testing or medical assessment is required.
Why Hormone Lab UK uses ZRT Laboratory
All samples are analysed by ZRT Laboratory, a CLIA-certified diagnostic laboratory specialising in convenient hormone and wellness testing. ZRT uses advanced LC-MS/MS methods and has developed minimally invasive saliva and dried-urine collection options that allow customers to complete specialist testing from home.
Through Hormone Lab UK, you receive the complete collection kit, specialist laboratory analysis and a clear personalised report without needing to attend a clinic.
Order the SU-840 Neurotransmitter & Hormone Test
If changes in mood, stress tolerance, sleep, energy, concentration, menstrual wellbeing or libido are affecting your quality of life, this comprehensive profile may provide useful additional information to discuss with your healthcare professional. Order online for convenient home collection and specialist laboratory analysis.