Blog — thyroid hormone

Part 1-Clearing up Confusion about Reverse T3: The Deiodinases & Thyroid Hormone Bioavailability

Posted by Ben White on

Part 1 By Margaret Groves, ZRT Laboratory Thyroid hormones are essential for the normal metabolic functioning of all tissues in the body, and a wide array of symptoms are therefore associated with abnormalities in thyroid hormone production and activation. Even when apparently adequate amounts of thyroxine are produced by the thyroid gland, thyroid function is profoundly affected by anything that disrupts conversion of thyroxine (T4) to the active thyroid hormone, triiodothyronine (T3). This conversion takes place primarily at the cellular level within tissues; only 20% of circulating T3 is generated by conversion of T4 within the thyroid gland itself. The deiodinases...

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Thyroid Synthesis and Selenium: A Closer Look

Posted by Ben White on

As Goldilocks said of her porridge, this one’s too cold, this one’s too hot, and this one’s just right. If your body isn’t making the right amount of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), you’re likely to find yourself on either side of “just right”.   Is It Frank or Functional Hypothyroidism? Most people who suffer from thyroid issues fall into the “too cold” category of body temperature dysregulation and just don’t make enough thyroid hormones T4 and T3, referred to as hypothyroidism. T3 action in the mitochondria increases metabolism and is responsible for heat production. Mitochondria are...

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