Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — hormone therapy monitoring

When sex hormone test results show both oestradiol (E2) and progesterone (Pg) within normal ranges, yet symptoms persist, the Pg/E2 ratio provides a critical additional layer of clinical insight. A low ratio points to oestrogen dominance; a high ratio to progesterone dominance — each requiring a different therapeutic response. This article explains how the ratio is calculated, when it is clinically relevant, and how a real-world case illustrates its practical value.

Over 25 million women enter menopause each year and face decisions about hormone replacement therapy. But HRT dosing is far from standardised — and the testing method used makes all the difference. This article explores why doses vary so widely and how saliva, blood spot and urine testing can help optimise outcomes.

Estrogen dominance — an excess of oestrogen relative to progesterone — is one of the most common hormonal imbalances in women. From heavy periods and mood swings to breast tenderness and weight gain, the symptoms are wide-ranging. Discover the causes, what to test, and how to restore balance.

In 1999, Tina Mattern was diagnosed with breast cancer and faced a terrifying choice of conventional treatments. Instead, she discovered the work of Dr. David Zava and ZRT Laboratory, and chose a path of natural hormone balancing, saliva testing and lifestyle change. This is her story — and her happy ending.

Explore why many men on topical testosterone replacement therapy may be unintentionally over-dosed due to outdated serum testing methods and misunderstood dosing principles. Learn how saliva and dried blood spot testing better reflect bioavailable testosterone delivered to tissues, why physiological dosing matters, and how excessive testosterone may suppress natural hormone production, reduce receptor sensitivity, and negatively affect long-term symptom management and hormonal balance.