Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — healthy endocrine function

Single nucleotide variations (SNVs) in the enzymes that metabolise estrogen can significantly alter breast cancer risk — in some cases by as much as 12-fold when multiple variants combine. In this detailed scientific overview, Jillian Harrington PhD of ZRT Laboratory explains how variations in CYP11A1, CYP19A1 (aromatase), CYP1B1, COMT and MnSOD affect the estrogen metabolism pathway, why catechol estrogens are dangerous, and how methylation testing can reveal individual vulnerability.

As the days shorten and sunlight fades, four key hormonal systems come under pressure: vitamin D, serotonin, cortisol and melatonin. For those susceptible to Seasonal Affective Disorder (SAD), the disruption of these interconnected rhythms can trigger depression, fatigue, poor sleep and low mood. This article explains the science behind the SAD hormone pattern — and what you can do to support your body through the darker months.

Iodine is an essential component of thyroid hormones T3 and T4, and plays a broader role in antioxidant defence and breast health. Yet many people are unknowingly deficient. This guide covers the recommended daily allowances for different life stages, the best dietary sources of iodine — from kelp to cod — and when testing your iodine and thyroid levels may be warranted.