Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — insulin sensitivity

When a patient with PCOS or weight issues is told “your blood sugar is normal,” the story is far from over. In this clinical article, Dr. Alison McAllister of ZRT Laboratory explains why insulin — not glucose — is the primary driver of PCOS symptoms, weight gain, testosterone and DHEAS excess, and cortisol dysfunction. Understanding the progression from insulin resistance to hyperinsulinemia to type 2 diabetes is essential for identifying and treating PCOS at the earliest possible stage.

The gut microbiome and estrogen are more closely connected than most people realise. As estrogen declines in menopause, microbial diversity falls with it — triggering a cascade of metabolic consequences including weight gain, abdominal fat, inflammation and reduced insulin sensitivity. Dr. Kate Placzek explores the science behind the estrobolome and explains why supporting both gut health and hormone balance is essential for metabolic wellbeing in menopause.