Male / Female Blood Spot LCMS Hormones 7 with SHBG and Thyroid is designed to measure the ten following 13 essential hormones accurately:
1- Estrone Hormone (E1)
2- Estradiol (Estrogen) (E2),
3- Estriol Hormone (E3),
4- Progesterone (Pg),
5- Testosterone (T),
6- DHEA-S (DS),
7- Sex Hormone Binding Globulin (SHBG),
8- Cortisol (C),
9- Thyroid Stimulating Hormone (TSH),
10- Free Triiodothyronine (fT3),
11- Free Thyroxine (fT4),
12- Thyroid Peroxidase Antibody (TPOab).
13- Sex Hormone Binding Globulin (SHBG)
14 - Thyroglobulin (Tgbn),
15 - Total Thyroxine (tt4)
Test Result: You will receive your test result 3-5 working days after the laboratory receives your sample. You will see your hormone levels in graphics and numbers on your test results. You will also see laboratory comments by Hormone Specialist PhD Dr in the comments: you will find Dr analysis of your hormone levels and what to do next.
- Collect samples from the comfort of your home and post them to our lab.
- The test must be used within 12 months after the purchase date.
- The test kit includes a laboratory fee: no additional laboratory cost and tax.
- Customers are responsible for shipping their samples to the laboratory.
- Click the link to see the Sample Test Result Report in Blood Spot
Having too much or too little of a particular hormone in the body can cause hormonal imbalance. This test can uncover whether you are expediting a hormonal imbalance that could be affecting your fertility. This test also allows you to track your hormone levels to understand how they change over time. Tracking your hormone levels over time can also tell you whether your hormone levels are decreasing with age.
Symptoms related to Hormonal Imbalance in Women include:
- Burned Out Feeling
- Hot Flashes
- Decreased Sweating
- Cold Body Temperature,
- Decreased Stamina
- Decreased Flexibility
- Slow Pulse Rate
- Memory Lapses
- Sleep Disturbances
- Poor Concentration
- Dizzy spells
- Mood Swings
- Decreased Mental Sharpness
- Nervous
- Headaches
- Depressed
- Apathy
- Anxious
- Stress
- Aggressive Behaviours
- Irritable
- Difficulty Sleeping
- Mental Fatigue
- Morning Fatigue
- Increased Forgetfulness
- Evening Fatigue
- Tearful
- Allergies
- Sensitivity to Chemicals
- Elevated Triglyceride
- Breast Cancer
- Fibrocystic Breasts
- Decreased Urine Flow,
- Increased Urinary Urges
- Incontinence
- Bone Loss
- Decreased Muscle Size
- Swelling or Puffy Eyes/face
- Nails Breaking or Brittle
- Rapid Heartbeat
- Low Blood Sugar
- High / Low Blood Pressure
- Heart Palpitations
- High Cholesterol
- Loss Scalp Hair
- Oily Skin or Hair
- Increase Facial or Body Hair
- Acne
- Thinning skin
Hormone Imbalances in Men and Women
Estradiol (Estrogen) and Progesterone Imbalance
Estradiol and progesterone levels—and especially their ratio—are key indicators of estrogen–progesterone balance in both women and men.
In women of reproductive age, excess estradiol relative to progesterone (often referred to as estrogen dominance) may contribute to symptoms such as premenstrual syndrome (PMS), fibrocystic or tender breasts, endometrial hyperplasia, and uterine fibroids. In peri-menopause, estrogen levels may fluctuate widely while progesterone declines, leading to similar symptoms including mood changes, water retention, weight gain, and thyroid dysfunction. In post-menopausal women using estrogen alone, inadequate progesterone may further worsen estrogen dominance. If left uncorrected, long-term estrogen dominance may increase the risk of insulin resistance and hormone-related cancers.
With menopause, declining ovarian production of both estradiol and progesterone can also lead to low estrogen symptoms, including hot flushes, night sweats, vaginal dryness, sleep disturbance, cognitive “brain fog,” accelerated skin ageing, and bone loss.
In men, estradiol is also essential for bone health, brain function, and cardiovascular health. However, elevated estrogen relative to progesterone or testosterone may contribute to weight gain, reduced libido, fatigue, mood changes, and gynecomastia. Maintaining balanced estradiol levels, appropriately regulated by progesterone and testosterone, is vital for optimal male health as well.
Testosterone and Sex Hormone Binding Globulin (SHBG) Imbalance
Testosterone is essential for sexual health, energy, muscle mass, bone density, and psychological well-being in both men and women.
Excess testosterone may cause acne, oily skin, and excess body or facial hair in women and is commonly associated with conditions such as polycystic ovary syndrome (PCOS), which is often linked to insulin resistance. In men, excessively high testosterone may contribute to irritability, sleep disturbances, and hormonal imbalance.
Low testosterone can occur in both sexes due to chronic stress, medications, hormonal contraception, ageing, or surgical removal of the ovaries or testes. Symptoms may include low libido, fatigue, depression, thinning skin, vaginal dryness (in women), loss of muscle and bone mass, and cognitive difficulties.
Sex Hormone Binding Globulin (SHBG) is a protein produced by the liver that binds to testosterone and estradiol, regulating how much of these hormones are biologically active. SHBG levels reflect total estrogen exposure—from natural production, hormone therapy, oral contraceptives, or dietary phytoestrogens. SHBG is also used to calculate free (unbound) testosterone when blood spot testing is used, providing a more accurate picture of hormone availability to tissues.
DHEA Hormone Imbalance
DHEA is produced by the adrenal glands and circulates mainly as DHEA-S. It is a key precursor to both estrogens and androgens and serves as an important marker of adrenal function. DHEA levels peak in early adulthood and gradually decline with age in both men and women.
Low DHEA may be associated with fatigue, reduced libido, low mood, and decreased stress resilience. Elevated DHEA may lead to androgen-related symptoms and, in women, can cause masculinising effects due to increased conversion to testosterone. Because DHEA influences multiple hormone pathways, it is essential to monitor DHEA alongside estrogen and testosterone, particularly during supplementation.
Cortisol Hormone Imbalance
Cortisol reflects adrenal health and the body’s response to physical and emotional stress. Under healthy conditions, cortisol follows a daily rhythm—highest in the morning and lowest in the evening.
Low cortisol levels may indicate reduced stress tolerance and are associated with fatigue, blood sugar instability, and immune dysfunction. Chronically elevated cortisol, often due to prolonged stress, is linked to serious long-term health risks in both men and women, including metabolic imbalance, osteoporosis, cardiovascular disease, and cognitive decline.
Thyroid Hormone Imbalance (Free T4, Free T3, TSH, TPO Antibodies)
Thyroid hormones regulate metabolism, energy production, temperature control, and overall vitality. Imbalances can cause symptoms such as persistent fatigue, feeling cold, low stamina, weight gain, depression, reduced libido, and elevated cholesterol in both sexes.
Thyroid dysfunction can also contribute to infertility, which is why these markers are included in fertility-focused hormone profiles, particularly for women.
When to Test
If you are experiencing any of these symptoms—or a combination of them—it may indicate an underlying hormone imbalance. Our comprehensive fifteen-panel Blood Spot hormone test provides a detailed assessment of key hormones in both men and women, helping to identify imbalances and support targeted, informed health decisions.
How to Use
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