Blood Spot LCMS Hormones 7 with SHBG is designed to measure the six following essential hormones accurately:
1- Estrone Hormone (E1)
2- Estradiol (Estrogen) (E2),
3- Estriol Hormone (E3),
4- Progesterone (Pg),
5- Testosterone (T),
6- DHEA-S (DS),
7- Cortisol (C),
8- Sex Hormone Binding Globulin (SHBG),
Test Result: You will receive your test result 3-5 working days after the laboratory receives your sample. You will see your hormone levels in graphics and numbers on your test results. You will also see laboratory comments by Hormone Specialist PhD Dr in the comments: you will find an analysis of your hormone levels and what to do next.
- Collect samples from the comfort of your home and post them to our lab.
- The test must be used within 12 months after the purchase date.
- The test kit includes a laboratory fee: no additional laboratory cost or tax.
- Customers are responsible for shipping their samples to the laboratory.
- Click the link to see the Sample Test Result Report in Blood Spot
Too much or too little of a particular hormone in the body can cause hormonal imbalance.
The Female Hormone Blood test can tell you whether a hormonal imbalance or thyroid problem may be causing your symptoms. This test can also uncover whether a hormonal imbalance affects your fertility.
Symptoms related to Hormonal Imbalance in Women include:
- Burned Out Feeling
- Hot Flashes
- Decreased Sweating
- Cold Body Temperature
- Decreased Stamina
- Decreased Flexibility
- Slow Pulse Rate
- Memory Lapses
- Sleep Disturbances
- Poor Concentration,
- Dizzy spells
- Mood Swings
- Decreased Mental Sharpness
- Nervous
- Headaches
- Depressed
- Apathy
- Anxious
- Stress
- Aggressive Behaviours
- Irritable
- Difficulty Sleeping
- Mental Fatigue
If you are experiencing any or a combination of those, it’s worth checking your hormone level imbalance using our comprehensive six-panel Blood Spot hormone test.
This test will enable you to see if there is any hormonal imbalance in your body and if it is needed to talk to your doctor.
Why Profiles?
When patients have hormone-related symptoms, it is usually not a clear-cut case of one hormone level being abnormal or even one hormone system. Because hormones play a role as chemical messengers to wake up the genome in specific target tissues throughout the body, it makes sense that all hormone systems work together to maintain a balance. This could be like the instruments in an orchestra playing together in harmony. The overall harmony is affected when one instrument is off-key or playing too loudly or softly (analogous to too much or too little hormone). Similarly, the adrenal, thyroid, and sex hormones work in harmony, and when one or more of the hormones in any system becomes unbalanced, this affects the harmony or balance of the whole system. Symptoms common to hormonal imbalances in the endocrine systems are seen as the body struggles to maintain balance but fails. Without an overall picture of which hormone systems are affected, it is often difficult to know the best clinical course of action for correcting the imbalance.
Hormone “Profiles” at ZRT are multiple hormone tests bundled into one convenient kit. Priced lower than the sum of the individual tests, these provide a more economical method to assess a patient’s overall hormonal status, giving a better picture of the hormone imbalances causing symptoms. For example, instead of treating a secondary hormonal imbalance caused by an abnormality in only one of the hormonal systems (e.g., hot flashes caused by low estradiol), you can address the underlying issues that lie at the root of the problem and, therefore, better guide your patients towards the overall wellness.
The Hormones Tested in Our Profiles and Why (for Men and Women)
Estradiol and Progesterone
Estradiol and progesterone play a central role in hormonal balance for both women and men. Their levels—and the balance between them—are key indicators of overall endocrine health. When estradiol is too high relative to progesterone, symptoms associated with estrogen dominance may occur. In women, this can contribute to premenstrual symptoms, breast tenderness, uterine changes, weight gain, fluid retention, mood changes, and thyroid imbalance. Similar imbalances can also affect men, leading to weight gain, fatigue, reduced libido, and mood disturbances.
As women approach menopause, fluctuating or declining ovarian hormone production can cause symptoms such as hot flashes, night sweats, sleep disruption, cognitive changes, vaginal dryness, accelerated skin aging, and bone loss. In men, gradual changes in sex hormone balance with age can affect energy levels, bone density, and cardiovascular health. Maintaining appropriate estradiol levels, balanced with progesterone, is essential for long-term health in both sexes.
Testosterone and SHBG (Sex Hormone Binding Globulin)
Testosterone is vital for muscle mass, bone strength, mood, energy, and sexual function in both men and women. Levels that are too high or too low can cause symptoms. Excess testosterone may contribute to acne, oily skin, and unwanted hair growth, while low testosterone is associated with reduced libido, low energy, loss of muscle and bone mass, mood changes, and cognitive difficulties.
SHBG is a protein produced by the liver that binds to estradiol and testosterone in the bloodstream, regulating how much of these hormones are biologically active. SHBG levels provide insight into overall estrogen exposure and are used to calculate free (unbound) testosterone when blood spot testing is performed. Balanced SHBG levels are essential for optimal hormone availability to tissues.
DHEA (Dehydroepiandrosterone / DHEA-S)
DHEA is produced by the adrenal glands and circulates mainly as DHEA-S. It serves as a precursor to both estrogens and androgens and reflects adrenal function. DHEA production peaks in early adulthood and gradually declines with age.
Adequate DHEA supports vitality, immune function, and well-being. Low levels may be associated with low libido, fatigue, and reduced resilience to stress, while high levels can contribute to androgen-related symptoms. Because DHEA converts into other sex hormones, monitoring DHEA alongside estrogen and testosterone is particularly important during supplementation.
Cortisol
Cortisol is a key marker of adrenal function and the body’s response to stress. Under healthy conditions, cortisol follows a daily rhythm—highest in the morning and gradually declining throughout the day.
Low cortisol may indicate reduced stress resilience and can be associated with fatigue, blood sugar instability, and immune dysfunction. Chronically elevated cortisol reflects prolonged stress exposure and is linked to long-term health risks, including metabolic imbalance, bone loss, cognitive decline, and cardiovascular concerns.
Thyroid Hormones (Free T4, Free T3, TSH, TPO Antibodies)
Thyroid hormones regulate metabolism, energy production, body temperature, and overall vitality. Imbalances can cause symptoms such as persistent fatigue, feeling cold, weight gain, low mood, reduced libido, and elevated cholesterol in both men and women. Thyroid dysfunction can also impair fertility, which is why these markers are included in fertility-focused profiles.
Together, these hormone markers provide a comprehensive view of endocrine health, helping to identify imbalances that may affect energy, mood, metabolism, reproductive health, and long-term well-being in both men and women.
How to Use
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