Male Saliva Steroid LC-MS Hormone Profile 7 (Pg, T, DHEAS, C, E1, E2,E3)

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Male Saliva Steroid LC-MS Hormone Profile 7 will test 7 hormones via LC-MS that is available for malesincluding estradiol (E2), estrone (E1), estriol (E3), progesterone (Pg), testosterone (T), dehydroepiandrosterone sulfate (DHEAS), and cortisol (C).  

LCMS could refer to Liquid Chromatography Mass Spectrometry, an analytical chemistry technique that identifies and measures large non-volatile samples. LCMS/MS, or Liquid Chromatography-tandem Mass Spectrometry, has grown significantly in clinical laboratories over the past 15 years.

Test is specifically designed to assess the levels of seven crucial hormones in the male body using saliva samples. Our advanced laboratory conducts the following tests to measure these hormones:

  • Testosterone (T): The testosterone test evaluates the levels of this primary male sex hormone that is vital for sexual development, muscle growth, bone density, and overall male health.
  • DHEAS (DS): This test measures the levels of DHEAS (dehydroepiandrosterone sulfate), an androgen hormone produced by the adrenal glands that contribute to overall hormone balance and well-being in men.
  • Progesterone (Pg): The progesterone test assesses the levels of this hormone, which is predominantly associated with female reproductive health but also plays a role in male hormonal balance.
  • Cortisol (C): The cortisol test measures cortisol levels, often referred to as the "stress hormone," which is involved in regulating stress responses, metabolism, and overall body functioning.
  • Estrone (E1): Estrone, one of the three main forms of estrogen, plays a crucial role in maintaining hormonal balance and overall well-being. It empowers individuals to gain valuable insights into their estrone levels, allowing for early detection of deficiencies that may contribute to various health concerns.
  • Estradiol (E2): This hormone, a type of estrogen, is responsible for various aspects of male reproductive health.
  • Estriol Hormone (E3) is one of three hormones of Estrogen hormones. It is designed to accurately assess the estriol level in  men’s bodies. 

By analyzing these hormone levels through the Male Saliva Steroid LC-MS Hormone Profile 7, we can provide valuable insights into your hormonal balance and overall well-being. This information can help identify any imbalances or deficiencies, guiding appropriate interventions and treatments to optimize your hormonal health.

Key Features

  • Comprehensive Hormone Analysis: TheMale Saliva Steroid LC-MS Hormone Profile 7 offers a comprehensive analysis of your hormone levels. It covers essential hormones relevant to male health and well-being.
  • Convenient Home Collection: Collect samples from the comfort of your home and post them to our lab. The test provides a hassle-free experience by eliminating the need for clinic visits.
  • Hormonal Health Insights: The test provides valuable insights into male hormonal health, including reproductive health, energy levels, stress response, and overall well-being.
  • Test Result Delivery: Receive your test result 3-5 working days after the laboratory receives your sample. The results are provided in an easy-to-understand format, combining graphics and numerical values.
  • Expert Laboratory Comments: Alongside the test results, you will find laboratory comments by a Hormone Specialist PhD Dr. These comments offer an in-depth analysis of your hormone levels and provide insights into the implications for your health.
  • Actionable Recommendations: The comments by the Hormone Specialist PhD Dr. will also include recommendations on what to do next based on the analysis of your hormone levels. This helps you understand how to optimize your hormone balance and overall well-being.
  • Personalized Assessment: The test results offer an individualized assessment of hormone levels, enabling personalized treatment plans and interventions based on your specific hormone profile.
  • Identification of Imbalances: The test helps identify potential hormonal imbalances, such as low or high hormone levels, which can contribute to various symptoms or health concerns.
  • Guidance for Interventions: With the test results, healthcare professionals can develop informed treatment plans tailored to address any imbalances or deficiencies. This includes targeted interventions such as lifestyle modifications, hormone replacement therapy, or other appropriate treatments.
  • Improved Symptom Management: Addressing hormone imbalances identified through the test can lead to improved symptom management for conditions related to hormonal fluctuations, such as fatigue, mood changes, low libido, or muscle loss.
  • Early Detection and Prevention: The test aids in the early detection of hormonal imbalances, allowing for timely interventions and preventive measures. This can help prevent the development or progression of hormonal disorders or associated health conditions.
  • Guidance from Healthcare Professionals: Test results can be interpreted by healthcare professionals who can provide expert guidance, explain the implications of hormone levels, and assist in developing a personalized plan to optimize hormonal health.
  • Suitable for All Ages: The test is suitable for both adults and children. It covers hormone levels that are relevant to male health across different age groups.
  • Long Shelf Life: The test must be used within 12 months after the purchase date, ensuring that you have ample time to take the test at your convenience.
  • All-Inclusive Pricing: The test kit includes a laboratory fee, eliminating the need for any additional laboratory costs or taxes. You pay a single price for the test kit, which covers both the analysis and the expert comments.
  • Customer Responsibility for Shipping: Customers are responsible for shipping their saliva samples to the laboratory. Clear instructions will be provided in the test kit to guide you through the process, ensuring the safe and timely delivery of your sample.
  • Confidential and Convenient: The test ensures confidentiality and privacy, with the convenience of sample collection from home, eliminating the need for clinic visits or blood draws.
  • How and when to Collect your saliva samples: Saliva Testing Instructions
  • Click to see >> Sample Saliva Test Result Report

 SYMPTOMS

Male Estrogen / Progesterone deficiency symptoms:

While estrogen and progesterone are primarily associated with female reproductive functions, they also play a role in the male body. In males, a deficiency in estrogen and progesterone can occur due to various reasons, such as hormonal disorders, certain medications, or aging. However, it's important to note that estrogen and progesterone deficiencies are less common in males compared to females.

Symptoms of estrogen and progesterone deficiency in males may include:

  • Bone loss: Estrogen helps maintain bone density in both males and females. A deficiency can lead to decreased bone density and an increased risk of osteoporosis.
  • Depressed mood: Hormonal imbalances can affect mood and contribute to feelings of depression or mood swings.
  • Heart palpitations: Estrogen and progesterone influence cardiovascular health, and their deficiency may contribute to heart palpitations or irregular heart rhythms.
  • Hot flushes: Although hot flushes are commonly associated with menopause in females, some males may experience similar symptoms with estrogen and progesterone imbalances.
  • Neck or back pain: Hormonal imbalances can sometimes cause muscle and joint discomfort, which may manifest as neck or back pain.
  • Night sweats and sleeping difficulties: Similar to females experiencing hormonal fluctuations during menopause, males with estrogen and progesterone deficiencies may experience night sweats and difficulties sleeping.


Male Estrogen Dominance/ Progesterone deficiency symptoms:

While estrogen dominance and progesterone deficiency are more commonly associated with females, hormonal imbalances can also occur in males. It's important to note that these imbalances are relatively rare in men compared to women. Here are some symptoms that can be associated with male estrogen dominance or progesterone deficiency:

  • Cold body temperature: Estrogen helps regulate body temperature, and its dominance in males may contribute to feeling cold more frequently than usual.
  • Irritability: Hormonal imbalances, including estrogen dominance, can affect mood and lead to increased irritability or mood swings.
  • Low libido: Testosterone is the primary hormone responsible for libido in both men and women. However, estrogen dominance or progesterone deficiency can disrupt the hormonal balance, potentially resulting in a decreased sex drive.
  • Prostate problems: Estrogen dominance in males may interfere with prostate health, potentially contributing to conditions such as benign prostatic hyperplasia (BPH) or prostate inflammation.
  • Increased urinary urge: Estrogen dominance can impact the urinary system, leading to an increased urge to urinate more frequently.
  • Decreased urine flow: An imbalance between estrogen and progesterone may affect the prostate gland and urinary system, causing a decrease in urine flow or difficulties with urination.
  • Breast or hip weight gain: Estrogen dominance can result in the accumulation of fat in certain areas, including the breasts or hips. This can lead to weight gain in these specific regions.

Male Low Androgens (DHEA/Testosterone Deficiency) Symptoms:

Low androgen levels, such as DHEA (dehydroepiandrosterone) and testosterone deficiencies, can occur in males and may lead to a variety of symptoms. Here are some symptoms that can be associated with low androgen levels in men:

  • Allergies: While not directly caused by low androgens, some studies suggest that low testosterone levels may contribute to an increased risk of developing allergies or experiencing more severe allergic reactions.
  • Apathy: Low androgens can affect mood and lead to feelings of apathy, lack of motivation, or a general sense of indifference.
  • Cold body temperature: Low androgens may impact the regulation of body temperature, leading to a sensation of feeling cold more often.
  • Bone loss: Androgens, particularly testosterone, play a role in maintaining bone density. Deficiencies in these hormones can contribute to decreased bone density and an increased risk of osteoporosis.
  • Burned-out feeling: Low androgens can contribute to a sense of burnout, chronic fatigue, or feeling depleted physically and mentally.
  • Depressed mood: Hormonal imbalances, including low androgens, can affect mood and contribute to feelings of depression or sadness.
  • Decreased erections: Testosterone is important for sexual function, including the ability to achieve and maintain erections. Low androgens can lead to a decrease in erectile function.
  • Morning/evening fatigue: Fatigue, particularly in the mornings or evenings, can be a symptom of low androgens.
  • Mental fatigue and decreased mental sharpness: Low androgens may contribute to mental fatigue, difficulties with concentration, and decreased cognitive sharpness.
  • Decreased flexibility: Androgens can influence muscle strength and flexibility. Low androgens may contribute to decreased flexibility and joint mobility.
  • Forgetfulness: Hormonal imbalances, including low androgens, can affect memory and contribute to forgetfulness or difficulties with recall.
  • Headaches: While not a direct symptom of low androgens, hormonal imbalances can sometimes contribute to headaches or migraines.
  • Heart palpitations: Hormonal imbalances, including low androgens, can affect cardiovascular health and contribute to heart palpitations or irregular heart rhythms.
  • Hot flushes: While commonly associated with menopause in females, some men with low androgens may experience hot flushes or sudden feelings of warmth.
  • Irritability: Hormonal imbalances can affect mood and contribute to increased irritability or mood swings.
  • Joint pain: Androgens have anti-inflammatory effects, and their deficiency may contribute to joint pain or discomfort.
  • Low libido: Testosterone is the primary hormone responsible for libido in both men and women. Low androgens can contribute to a decreased sex drive.
  • Decreased muscle size: Androgens, particularly testosterone, are crucial for maintaining muscle mass. Low androgens can lead to a decrease in muscle size or muscle wasting.
  • Muscle soreness: Low androgens may contribute to increased muscle soreness or difficulties with muscle recovery after physical activity.
  • Night sweats: Hormonal imbalances, including low androgens, can contribute to night sweats or excessive sweating during sleep.
  • Rapid aging: Androgens play a role in the aging process, and their deficiency may contribute to an accelerated appearance of aging, such as wrinkles or sagging skin.
  • Ringing in ears: While not directly caused by low androgens, some individuals with hormonal imbalances may experience tinnitus or ringing in the ears.
  • Skin thinning: Androgens contribute to the health and thickness of the skin. Low androgens can lead to skin thinning and increased vulnerability to skin damage.
  • Decreased stamina: Androgens play a role in energy production and stamina. Low androgens may contribute to decreased stamina or endurance.
  • Stress: Hormonal imbalances, including low androgens, can contribute to feelings of stress or an increased stress response.
  • Weight gain: Androgens are involved in regulating metabolism and body composition. Low androgens can contribute to weight gain, particularly increased fat mass.

Male high Androgens (DHEA/Testosterone deficiency) symptoms:

High androgen levels, including DHEA and testosterone, typically result in symptoms such as:

  • Acne: Increased androgen levels can stimulate sebum production, leading to oily skin and an increased likelihood of developing acne.
  • Aggressive behavior: Elevated androgens can contribute to increased aggression or irritability in some individuals.
  • Anxiety: While androgens are not typically associated with anxiety, hormonal imbalances can affect mood and potentially contribute to feelings of anxiety or restlessness.
  • High blood pressure: Androgens have complex effects on blood pressure regulation. In some cases, high androgen levels may contribute to increased blood pressure, although other factors, such as genetics and lifestyle, also play a role.
  • Oily hair or skin: Elevated androgen levels can lead to increased sebum production, resulting in oily hair and skin.
  • Irritability: Hormonal imbalances, including high androgen levels, can affect mood and contribute to increased irritability or mood swings.
  • Nervousness: While not a direct symptom of high androgens, hormonal imbalances can affect the nervous system and potentially contribute to feelings of nervousness or restlessness.
  • Sleeping difficulties: Hormonal imbalances, including high androgens, can sometimes disrupt sleep patterns and lead to difficulties falling asleep or staying asleep.
  • Sugar cravings: Androgens can influence metabolism and appetite regulation. In some cases, high androgen levels may contribute to increased sugar cravings or a preference for sugary foods.
  • Breast or hip weight gain: High androgen levels are not typically associated with weight gain in specific areas such as the breasts or hips. However, hormonal imbalances can affect overall body composition and lead to weight gain.

Male low Cortisol deficiency symptoms

Low cortisol levels in males, also known as cortisol deficiency or adrenal insufficiency, can lead to a variety of symptoms. Here are some symptoms that can be associated with low cortisol levels:

  • Low blood pressure: Cortisol helps regulate blood pressure, so low cortisol levels can lead to low blood pressure.
  • Low blood sugar: Cortisol is involved in regulating blood sugar levels, and its deficiency can result in low blood sugar (hypoglycemia).
  • Chemical sensitivity: Some individuals with low cortisol levels may be more sensitive to chemicals or environmental triggers.
  • Depressed mood: Hormonal imbalances, including low cortisol levels, can affect mood and contribute to feelings of depression or sadness.
  • Dizzy spells: Low cortisol levels can lead to dizziness or lightheadedness, especially upon standing up.
  • Fatigue: Cortisol plays a role in energy production, and its deficiency can contribute to persistent fatigue or lack of energy.
  • Infertility: In some cases, low cortisol levels may affect reproductive function and contribute to infertility or decreased fertility.
  • Irritability: Hormonal imbalances can affect mood and contribute to increased irritability or mood swings.
  • Joint pain: Cortisol has anti-inflammatory properties, and its deficiency can lead to joint pain or discomfort.
  • Decreased mental sharpness: Low cortisol levels can affect cognitive function and lead to decreased mental sharpness or difficulties with concentration and memory.
  • Slow pulse rate: Cortisol deficiency can sometimes contribute to a slow pulse rate.
  • Decreased stamina: Cortisol plays a role in energy metabolism and stamina. Its deficiency can lead to decreased stamina or endurance.
  • Stress: Cortisol is often referred to as the "stress hormone" because it helps regulate the body's stress response. Low cortisol levels may affect the body's ability to manage stress effectively.
  • Sugar cravings: Cortisol deficiency can disrupt appetite regulation, leading to increased cravings for sugary foods or carbohydrates.
  • Swelling or puffy eyes/face: Cortisol deficiency can contribute to fluid retention, which may result in swelling or puffiness, particularly around the eyes or face.

Male high Cortisol deficiency symptoms:

Cortisol deficiency, also known as adrenal insufficiency or hypocortisolism, can lead to a variety of symptoms. However, it is important to note that the symptoms you mentioned are not exclusively associated with cortisol deficiency and can be seen in other medical conditions as well. Additionally, it's crucial to consult a healthcare professional for a proper diagnosis and evaluation. That being said, here is some information on the potential symptoms of cortisol deficiency in males:

  • Fatigue: Individuals with cortisol deficiency may experience persistent fatigue and lack of energy.
  • Weight loss: Cortisol deficiency can lead to unintentional weight loss, rather than weight gain.
  • Low blood pressure: Cortisol plays a role in maintaining blood pressure levels, so a deficiency can result in low blood pressure rather than high blood pressure.
  • Gastrointestinal symptoms: Digestive issues such as nausea, vomiting, abdominal pain, and diarrhea can occur.
  • Low blood sugar: Cortisol helps regulate blood sugar levels, and a deficiency can cause hypoglycemia (low blood sugar), which may manifest as sugar cravings.
  • Dizziness: Some individuals with cortisol deficiency may experience dizziness or lightheadedness.
  • Darkened skin: In cases of long-standing cortisol deficiency, a condition called Addison's disease, hyperpigmentation or darkening of the skin can occur, especially in areas exposed to the sun and pressure points.
  • Decreased libido: Reduced sexual desire or erectile dysfunction can be observed in some males with cortisol deficiency.

Why do we test hormones in saliva, and what Benefit of Saliva Testing?

Testing hormones in saliva has several benefits compared to other testing methods:

  • Non-invasive: Saliva testing is a non-invasive method that only requires the patient to spit into a collection tube. This makes it a more comfortable and convenient option for hormone testing compared to blood or urine tests.
  • Home collection: Saliva testing allows patients to collect samples in the comfort of their own homes. This eliminates the need for multiple visits to a healthcare facility and allows for specific timed collections, which is important for accurately measuring hormone levels.
  • Bioavailable hormone levels: Saliva testing measures the bioavailable hormone levels, which refers to the fraction of hormones that are unbound and active, available to target tissues. This is important because it reflects the hormones that are actually exerting their effects in the body, as opposed to total hormone levels that may include hormones bound to carrier proteins.
  • Symptom correlation: Saliva testing is particularly useful for correlating hormone levels with specific symptoms of excess or deficiency. Since saliva testing measures bioavailable hormone levels, it provides a better understanding of the hormone levels that may be contributing to specific symptoms experienced by an individual.
  • Hormone therapy monitoring: Saliva testing is a valuable tool for monitoring hormone therapy. It can help assess the effectiveness of hormone replacement or supplementation by measuring the levels of bioavailable hormones.

For males, saliva testing can provide a comprehensive profile of hormones such as cortisol, estrogen, progesterone, DHEA, and testosterone. This profile can help identify any imbalances or deficiencies in these hormones, which may be associated with various symptoms or conditions. The results of a male saliva profile test can guide healthcare professionals in formulating appropriate treatment plans or interventions to address any hormonal imbalances and optimize overall health and well-being.


How to Use 

how to collect saliva sample