Blog — hormones

By Tracy Tranchitella, ND, ZRT Laboratory The intricate interconnection between the human microbiome and the endocrine system highlights a significant communication network, wherein both systems profoundly influence one another. Particularly noteworthy is the relationship between estrogens and the gut microbiome. The estrobolome is the portion of the microbiome that influences estrogen metabolism. First defined in 2011, the estrobolome is the collection of all enteric bacteria capable of metabolizing estrogens (1). The estrobolome can impact endogenous estrogen metabolism by modulating the enterohepatic circulation of estrogens thus influencing plasma estrogen levels (2). Dysbiosis, diet, and gut infections can alter the microbial environment...

By Dr Nina Silberstein, BA. Women who are in perimenopause, menopause or post-menopause sometimes feel like they’re living in a different body. Many have a hard time losing or controlling their weight—whether it’s due to shifting and declining hormones and a slowing down of metabolism combined with stress. We sat down with integrative physician, Jade Teta, to talk about the role of hormones and weight, why he thinks some women are having difficulty losing or controlling their weight, and what they can do about it. As a practitioner of naturopathic medicine, Dr. Teta is an expert in nutrition, exercise, and...

By Dr. Tracy Tranchitella, ND (ZRT Laboratory) For anyone who has dealt with issues that are related to chronic fatigue has likely evaluated their hypothalamic–pituitary–adrenal (HPA) axis performance through a multi-point salivary test. The hormone Cortisol is measured in saliva when the samples are collected through predetermined intervals throughout a single day reveal one’s physiological resilience and metabolic reserve in response to daily stressors. HPA axis testing is a mainstay in the world of integrative, naturopathic, and functional medicine. For the past 2 years, the world has existed under the constant shadow of COVID-19. To say that we have been “stressed” is an...

Saliva testing is used for measuring hormones like cortisol, estrogen, progesterone, DHAES and testosterone, and its non-invasive collection asks patients to spit into a plastic tube. This sampling method allows patients to collect saliva at home at specific times, which is important for accurately measuring hormone levels. Why do we test hormones in saliva? Steroid hormones in the bloodstream are 95-99% bound to carrier proteins, and in this form are unavailable to target tissues. Saliva testing measures the amount of hormone available to target tissues – the bioavailable amount. For this reason, saliva testing better relates to specific symptoms of excess...

By ZRT Laboratory Consultants.  Menopause can be a confusing time for many women and their families, and as a society we tend to steer away from having open, honest conversations about this very important transition in a woman’s life. At ZRT, we aim to change that and equip all women with the tools and resources necessary to maintain optimal health during their menopause transition and after. In this post, ZRT’s Clinical Consultants tackle the most commonly asked questions and misunderstandings about menopause from patients. What Age Does Menopause Occur? Menopause is defined as the natural absence of menstrual periods for...