Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — hormone therapy effectiveness

When sex hormone test results show both oestradiol (E2) and progesterone (Pg) within normal ranges, yet symptoms persist, the Pg/E2 ratio provides a critical additional layer of clinical insight. A low ratio points to oestrogen dominance; a high ratio to progesterone dominance — each requiring a different therapeutic response. This article explains how the ratio is calculated, when it is clinically relevant, and how a real-world case illustrates its practical value.

Over 25 million women enter menopause each year and face decisions about hormone replacement therapy. But HRT dosing is far from standardised — and the testing method used makes all the difference. This article explores why doses vary so widely and how saliva, blood spot and urine testing can help optimise outcomes.