Blog — hormonal imbalance

The human microbiome and the endocrine system are deeply interconnected, engaging in a complex two-way conversation that influences everything from mood to metabolism. One of the most fascinating areas of this interaction centers on estrogen and the gut—a relationship governed by what’s now known as the estrobolome.

Infertility is an increasingly common issue, affecting over 22% of married women who struggle to conceive or carry a pregnancy to term. While physical causes like anovulation, tubal damage, or endometriosis account for many cases, hormonal imbalances are often overlooked yet highly treatable contributors to infertility. The ZRT Fertility Profile offers a comprehensive and convenient way to evaluate hormone levels that are essential for conception and pregnancy maintenance. By testing markers like FSH, LH, estradiol, progesterone, testosterone, thyroid hormones, and cortisol, this profile helps identify conditions such as ovarian insufficiency, luteal phase deficiency, PCOS, thyroid dysfunction, and stress-related hormonal disruption. Samples can be collected easily at home through fingerstick blood and saliva on specific days of the menstrual cycle, ensuring accurate and timely results. Early identification of hormonal imbalances empowers women to take corrective action—often through simple lifestyle changes or targeted therapies—before turning to more invasive fertility treatments. Whether you’ve been trying to conceive without success, experienced recurrent miscarriages, or are planning ahead for pregnancy, ZRT’s Fertility Profile provides critical insights to help you and your healthcare provider take proactive steps toward reproductive health and success.

The UK is facing a growing obesity crisis, with two-thirds of adults and a rising number of children classified as overweight or obese. A recent UK Parliament briefing highlights alarming trends, including regional and ethnic disparities and increased risks linked to socioeconomic status. While public health strategies continue to evolve, addressing the hormonal root of weight gain may offer a more effective, personalized solution. ZRT Laboratory’s Weight Management Profile helps uncover hidden hormonal imbalances—such as elevated cortisol, low testosterone, or thyroid dysfunction—that contribute to stubborn fat gain, poor metabolism, and increased disease risk.

Fertility Mapping: Navigating Fertility with PCOS and Insulin Resistance (Part II)By Dr. Alison McAllister Polycystic Ovary Syndrome (PCOS) is a complex, multifactorial condition influenced by disruptions in hormone receptors, metabolism, neurotransmitter function, and nutrient balance. As a lifelong disorder, PCOS is a leading contributor to infertility, weight gain, and an increased risk for cardiometabolic issues. In this blog post, we dive deeper into laboratory testing, helping healthcare providers understand which tests are critical for women suspected of having PCOS. Lab Testing for PCOS PCOS is most commonly diagnosed through the Rotterdam Criteria, a diagnostic framework that considers various indicators, including...

Diagnosing acne goes beyond a mere visual examination, determining its severity and potential underlying causes. This comprehensive evaluation by a medical professional helps tailor appropriate treatments to alleviate symptoms effectively.  Diagnostic Process: A General Practitioner (GP) conducts a thorough examination, observing the affected areas like the face, chest, or back to identify distinctive acne symptoms. The presence of blackheads, red nodules, or sore spots assists in categorizing acne severity. Assessing Acne Severity: The severity of acne typically falls into three categories, guiding the course of treatment: Mild Acne: Predominantly characterized by whiteheads and blackheads, occasionally accompanied by a few papules...