Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — Alzheimer's disease

Alzheimer's disease is a slow and devastating condition that affects memory, cognition, and the ability to perform everyday tasks. Sadly, women are disproportionately affected: by 2050, over 9 million out of 13.8 million Americans with Alzheimer’s will be women. But why are women at greater risk? The answers lie not only in longevity but in biology, hormones, brain structure, and how women respond to stress. What is Alzheimer’s? Alzheimer’s is the most common form of dementia, marked by the gradual loss of neurons and brain function. Characteristic features include the buildup of beta-amyloid plaques and tau tangles, excessive neural pruning,...

Perimenopause is far more than a reproductive transition — it is fundamentally neurological. As oestradiol declines, the brain’s bioenergetic system becomes compromised, neurotransmitter balance shifts, and the thermoneutral zone narrows, giving rise to hot flashes, mood instability, memory changes and sleep disruption. This article explores the neuroscience behind the menopausal transition and why hormone replacement therapy — timed correctly — may be the most effective intervention.

DHEA and DHEA-S are the most abundant steroid hormones in the body and play a critical role in brain health, mood regulation, and cognitive function. This article explains the biochemical distinction between the two, how they act as neurosteroids, and why measuring DHEA-S is the gold standard for assessing adrenocortical activity.