Test ID: SU-840 | Sample Type: Saliva + Dried Urine | Technology: LC-MS/MS | Results: 3–5 Working Days | Laboratory: ZRT Laboratory (CLIA-certified)
A Comprehensive View of Hormones and Neurotransmitter Pathways
The SU-840 Neurotransmitter & Hormone Test combines a seven-hormone saliva profile with an extensive dried-urine neurotransmitter panel. It is designed for people who want to explore how hormone status and systemic neurotransmitter pathways may relate to symptoms involving mood, stress, sleep, energy, concentration, menstrual health, or libido.
The saliva profile measures oestrogens, progesterone, testosterone, DHEA-S, and cortisol. The dried-urine profile measures serotonin, dopamine, GABA, glutamate, norepinephrine, and other neurotransmitters together with important precursors and metabolites.
Looking at both systems in one profile may provide more useful context than testing either hormones or neurotransmitters alone.
Important: Urinary neurotransmitter testing measures neurotransmitters, precursors, and metabolites excreted in urine. It does not directly measure neurotransmitter activity in the brain. This test cannot diagnose a hormonal, mental health, neurological, or sleep condition.
Could This Test Be Relevant to Your Symptoms?
You may wish to discuss this combined profile with a qualified healthcare professional if you have ongoing or unexplained symptoms such as:
- Persistent tiredness or fluctuating energy
- Low mood, irritability, or frequent mood changes
- Feeling anxious, tense, overwhelmed, or unable to switch off
- Poor concentration, forgetfulness, or mental fog
- Difficulty falling asleep, staying asleep, or waking refreshed
- Reduced motivation or enjoyment
- Low libido or changes in sexual wellbeing
- Menstrual changes, PMS, or premenstrual mood symptoms
- Hot flushes, night sweats, or vaginal dryness
- Changes in weight or body composition
- Reduced strength, stamina, or muscle mass
- Difficulty coping with everyday stress
What Does the Test Measure? (33 Markers)
Saliva Hormone Profile — 7 Markers
| Hormone Group | Markers Included |
|---|---|
| Oestrogens | Estradiol (E2), Estriol (E3), Estrone (E1) |
| Progesterone | Progesterone (Pg) |
| Androgens | Testosterone (T), DHEA-S (DS) |
| Stress hormone | Cortisol (C) |
Dried-Urine Neurotransmitter Profile — 26 Markers
| Pathway or Group | Markers Included |
|---|---|
| Serotonin and tryptophan | Tryptophan (Trp), Serotonin (5-HT), 5-HIAA |
| GABA, glutamate and amino acids | GABA, Glycine (Gly), Taurine (Tau), Glutamate (Glu), Glutamine (Gln) |
| Histamine | Histidine (His), Histamine (HIST), N-Methylhistamine (N-MeHist) |
| Phenylethylamine | Phenylethylamine (PEA) |
| Dopamine and catecholamines | Tyrosine (Tyr), Tyramine (Tyra), Dopamine (DA), DOPAC, HVA, Norepinephrine (NE), Normetanephrine (NMN), Epinephrine (Epi), VMA |
| Kynurenine pathway | Kynurenine (Kyn), Kynurenic Acid (KynAc), 3-Hydroxykynurenine (3OHKyn), Xanthurenic Acid (Xanth) |
| Sample correction | Creatinine (Crtn) |
Why Test Hormones and Neurotransmitters Together?
Hormones and neurotransmitter systems are biologically connected:
- Oestrogens interact with pathways involved in serotonin and other chemical messengers
- Progesterone and its metabolites interact with signalling related to GABA
- Testosterone and DHEA-S may be relevant to energy, motivation, and sexual wellbeing
- Cortisol is part of the stress-response system and overlaps with symptoms involving sleep, mood, and energy
- Neurotransmitter precursors and metabolites provide information about production, metabolism, and excretion across several systemic pathways
Combining these measurements may help a practitioner consider whether symptoms are occurring alongside identifiable hormone or neurotransmitter patterns.
How It Works
- Order your kit — delivered directly to your door
- Collect your saliva and dried urine samples at home using the provided materials and instructions
- Post your samples to the laboratory using the provided instructions
- Receive your results by email within 3–5 working days of the lab receiving your samples
Preparing for Your Test
Medicines, hormone therapy, supplements, food, drink, nicotine, exercise, and collection timing may influence results. Follow the instructions supplied with the kit and record all medicines, hormones, and supplements on the requisition form. Do not stop prescribed medication or hormone therapy unless your prescribing clinician advises you to do so.
If you menstruate, the ideal collection day may depend on your cycle and the clinical question. Urinary neurotransmitter results assume normal kidney function. If you are pregnant, breastfeeding, under 18, or have a diagnosed condition, obtain professional advice before ordering.
What You Receive With Your Results
- All 33 markers in numerical and graphical form with reference ranges
- Saliva hormone profile with specialist commentary
- Neurotransmitter pathway analysis including metabolites and precursors
- A written interpretation by a Hormone Specialist PhD Doctor
- Laboratory fee included — no hidden charges
Why We Use ZRT Laboratory
All samples are analysed by ZRT Laboratory — a CLIA-certified diagnostic laboratory specialising in convenient hormone and wellness testing. ZRT uses advanced LC-MS/MS methods and has developed minimally invasive saliva and dried-urine collection options that allow customers to complete specialist testing from home.
Hormone Lab UK (Testfield UK Ltd) is the official UK test provider for ZRT Laboratory.
Important Information
- Laboratory fee included — no hidden costs
- Customers are responsible for return shipping to the laboratory
- Test kit valid for 12 months from purchase date
Frequently Asked Questions
Who may consider this combined profile?
Adults experiencing persistent symptoms involving mood, energy, concentration, stress, sleep, menstrual wellbeing, menopausal changes, or libido. Because these symptoms have many possible causes, professional assessment remains important.
Can this test diagnose anxiety, depression, menopause, or a hormone disorder?
No. It cannot diagnose medical or psychiatric conditions. It provides biochemical information that may help you and your healthcare professional better understand your symptoms. Diagnosis requires appropriate professional assessment.
Why use saliva for hormone testing?
Saliva collection is non-invasive and convenient at home. It measures the unbound fraction of selected steroid hormones. Correct timing and careful collection are important for interpretable results.
Why use dried urine for neurotransmitter testing?
Dried urine collection is convenient, stable for transport, and avoids a 24-hour collection jug. Urinary testing provides information about systemic neurotransmitter production, metabolism, and excretion.
Can I take my usual medication and supplements?
Some medicines, hormones, and supplements can affect results. Follow the kit instructions and list everything you take. Never stop prescribed treatment without consulting your prescribing clinician.
Is this test suitable for children?
The collection methods may be used for children, but suitability should be discussed with a paediatrician. It does not replace developmental, endocrine, or mental health assessment.
Does the price include the laboratory fee?
Yes. The full laboratory analysis fee is included. Return postage to the laboratory is not included.
How long is the kit valid for?
The kit must be used within 12 months of the purchase date.
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