Elite Neurotransmitters & Saliva Hormone Test
(Saliva LCMS Hormones 7 + Dried Urine LCMS Neurotransmitters and Diurnal Hormones II)
Test ID: SU-842
This is an advanced functional assessment designed to evaluate the dynamic relationship between hormones and brain chemistry. This integrated profile combines 7 key sex and adrenal hormones measured in saliva with 50 dried urine neurotransmitters and diurnal hormone markers, totalling 57 tests, offering a comprehensive overview of hormonal balance, stress response, mood regulation, and neurochemical pathways. By analysing both endocrine and neurotransmitter systems together, the test helps identify imbalances that may contribute to symptoms such as anxiety, depression, ADHD, fatigue, sleep disturbances, and chronic stress.
LCMS Saliva Hormone Tests
- Estradiol (E2)
- Estriol (E3)
- Estrone (E1)
- Progesterone (Pg)
- Testosterone (T)
- Dehydroepiandrosterone Sulfate (DS)
- Cortisol (C)
LCMS Dried Urine Neurotransmitters Tests
- Tryptophan (Trp)
- Serotonin (5-HT)
- 5-Hydroxyindoleacetic Acid (5-HIAA)
- Gamma-Aminobutyric Acid (GABA)
- Glycine (Gly)
- Taurine (Tau)
- Glutamate (Glu)
- Glutamine (Gln)
- Histidine (His)
- Histamine (HIST)
- N-Methylhistamine (N-MeHist)
- Phenylethylamine (PEA)
- Tyrosine (Tyr)
- Tyramine (Tyra)
- Dopamine (DA)
- Dihydroxyphenylacetic Acid (DOPAC)
- Homovanillic Acid (HVA)
- Normetanephrine (NMN)
- Vanillylmandelic Acid (VMA)
- Kynurenine (Kyn)
- Kynurenic Acid (KynAc)
- 3-Hydroxykynurenine (3OHKyn)
- Xanthurenate (Xanth)
- Creatinine (Crtn) ×5
- Free Cortisol (FC) ×4
- Free Cortisone (FCn) ×4
- 6-Sulfatoxymelatonin (MT6s) ×4
- Norepinephrine (NE) ×5
- Epinephrine (Epi) ×5
Why Combine Hormones & Neurotransmitters?
Hormones and neurotransmitters function as an interconnected network, constantly influencing one another. Chronic stress can disrupt cortisol and dopamine balance, oestrogen plays a role in serotonin production, progesterone modulates GABA activity, and DHEA and testosterone affect motivation, resilience, and mood. Evaluating both systems together provides a clearer understanding of the root causes behind symptoms such as fatigue, anxiety, mood instability, low libido, PMS, insomnia, and burnout.
The Benefit of Adding Free Cortisol, Free Cortisone, Norepinephrine, Epinephrine, 6-Sulfatoxymelatonin & Creatinine
Including these markers alongside neurotransmitter testing significantly strengthens the clinical depth of the assessment by evaluating stress hormones, sympathetic nervous system activity, sleep regulation, and biochemical accuracy together.
Comprehensive Neuroendocrine Insight
This expanded panel integrates adrenal hormones, catecholamines, melatonin metabolism, and neurotransmitter pathways, providing a more complete overview of neuroendocrine balance and systemic regulation.
Advanced Stress Response Evaluation
Free Cortisol and Free Cortisone reflect adrenal output and daily stress adaptation, while Norepinephrine and Epinephrine assess sympathetic “fight-or-flight” activity.
Sleep & Circadian Rhythm Analysis
6-Sulfatoxymelatonin (MT6s), a metabolite of melatonin, provides insight into circadian rhythm regulation and sleep quality.
Creatinine Standardisation
Creatinine corrects for urine concentration variability, ensuring accurate and reliable interpretation of urinary hormone and neurotransmitter levels.
Key Features
Comprehensive Neurochemical Profile — Evaluates a broad spectrum of neurotransmitters to provide detailed insight into overall brain chemistry and functional balance.
Objective Biomarker Measurement — Delivers precise, quantitative data to support clinical assessment.
Personalised Treatment Planning — Identifies specific imbalances to help guide tailored interventions.
Treatment Monitoring — Allows practitioners to track biochemical changes over time.
Suitable for Adults and Children — Appropriate for both adult and paediatric use when clinically indicated.
Convenient At-Home Collection — Non-invasive dried urine sampling collected four times throughout the day.
Delivery: Free delivery in the UK.
Shipping: Customers are responsible for shipping their samples to the laboratory.
No Additional Fee: The test kit includes a laboratory fee: no additional laboratory cost or tax.
How and when to collect your saliva samples: Saliva Testing Instructions
Click to see >> Sample Saliva Test Result Report
Click to see >> Advanced Neurotransmitter Test Report
The test must be used within 12 months after the purchase date.
Test Result Report: You will receive your test result via email within 3-5 working days after the Laboratory receives your sample. On your test result, you will find your hormone levels in graphics and numbers. You will also find the Laboratory’s comments made by Specialist PhD. Dr suggesting how to balance your hormones and what to do next.
The Test Kit pack includes
- Test Requisition Form includes Symptom Checklist
- Requisition Form to complete, including your personal and medical history
- Contains collection instructions
- Urine Strips for collecting a dried urine sample and Tubes for collecting saliva samples
- Instructions on How to Use Collection Kit
- Return Envelope
- Shipping instruction
Neurotransmitters Play a Key Role
Regulation of Mood and Emotions
Neurotransmitters such as serotonin, dopamine, and norepinephrine are central to emotional balance, motivation, and the experience of pleasure and reward.
Control of Motor Functions
Acetylcholine, dopamine, and GABA are essential for coordinating movement, muscle control, balance, and overall motor stability.
Cognitive Function and Learning
Glutamate, acetylcholine, and dopamine contribute to memory formation, attention, concentration, and information processing.
Regulation of Sleep and Wakefulness
Serotonin and norepinephrine help regulate circadian rhythm and sleep architecture.
Autonomic Functions
Neurotransmitters regulate essential involuntary functions, including heart rate, blood pressure, digestion, and respiration.
Are You Affected?
Mood Disorders — Altered levels of serotonin, dopamine, and norepinephrine are frequently associated with depression, anxiety disorders, and bipolar disorder.
Cognitive Impairment — Neurotransmitter dysregulation can impair memory, focus, and processing speed.
Sleep Disturbances — Imbalanced neurotransmitters may disrupt sleep-wake cycles, contributing to insomnia or excessive daytime fatigue.
Digestive Disorders — Serotonin plays a significant role in gut function. Low or dysregulated levels may contribute to IBS and other functional digestive disturbances.
Neurotransmitters & Symptoms
If you regularly experience three or more of the following symptoms, a neurotransmitter imbalance may be contributing: ADD/ADHD, aggression, anxiety, fatigue, forgetfulness, hyperactivity, impulsive behaviours, insomnia, low libido, mood swings, OCD tendencies, panic attacks, poor concentration, PMDD, severe PMS, or persistent sleep problems.
Neurotransmitters You Should Know
Excitatory:
- Dopamine — the brain’s pleasure and reward centre; plays a central role in addiction, attention, focus, motivation, and movement control.
- Epinephrine and Norepinephrine — regulate the “fight or flight” response, elevate blood pressure and heart rate, stimulate wakefulness.
- Glutamate — the major excitatory neurotransmitter; decreases sleep, optimises learning, memory, and mood.
- Histamine — increases metabolism, promotes wakefulness, and suppresses appetite.
- PEA (phenylethylamine) — promotes energy, elevates mood, regulates attention and aggression; serves as a biomarker for ADHD.
Inhibitory:
- GABA — the major inhibitory neurotransmitter; improves mood, relieves anxiety, and promotes sleep.
- Glycine — improves sleep quality, calms aggression, and serves as an anti-inflammatory agent.
- Serotonin — the “happiness molecule”; contributes to calm and well-being, eases depression and anxiety, supports sleep, and decreases appetite.
Clinical Utility & Validity of Urinary Neurotransmitter Testing
Mood disorders are complex and often involve imbalances across multiple neurotransmitter systems interacting with hormones and the gut–brain axis. Urinary neurotransmitter testing provides objective biochemical data that helps identify specific excesses or deficiencies, supporting more targeted and personalised treatment strategies.
Dried Urine – A Convenient Option
Dried urine collection is non-invasive and simple to perform at home. Four small samples are collected at specific times during the day using filter cards. Once dried, the samples are mailed to the laboratory. This method improves convenience, compliance, and practicality in clinical use.
Considerations:
- The neurotransmitter test assumes proper kidney function. This test should not be used in individuals with compromised renal function.
- On the day of testing, restrict liquid intake to normal consumption.
- On the day of testing, avoid alcohol, nicotine, bananas, pineapple, and walnuts as they may interfere with testing.
