Male Hormone Test (Full Profile)

The male Hormone Test (Full Profile) is designed for test 27 following essential hormones and elements as follows: 

• Estradiol (Estrogen) (E2),
  
• Prostate-Specific Antigen (PSA),
  
• Testosterone (T), 
  
• DHEAS (DS), 
  
• Sex Hormone Binding Globulin (SHBG),  
  
• Cortisol (C), 
  
• Thyroid Stimulating (TSH),  
  
• Free Triiodothyronine  (fT3), 
  
• Free Thyroxine (fT4),
  
• Thyroid Peroxidase Antibody (TPO), 
  
• High Sensitivity C-Reactive Protein (hs-CRP),
  
• Thyroglobulin (Tgbn),
  
• Luteinising(Lh),
  
• Thyroxine (t4),
  
• Vitamin D 25-oh total - Testing Vitamin D2,
  
• Vitamin D 25-oh total - Testing Vitamin D3,
  
• Cadmium (Cd),
  
• Mercury (Hg),
  
• Selenium (Se),
  
• Zinc (Zn),
  
• Magnesium (Mg),
  
• Copper (Cu),
  
• Insulin (IN),
  
• Haemoglobin (HbA1c),
  
• Triglycerides (TG),
  
• Total Cholesterol (CH),
  
• HDL Cholesterol (HDL).
  

Test Result: You will receive your test result 3-5 working days after the laboratory receives your sample. You will see your hormone levels in graphics and numbers on your test results. You will also see laboratory comments by Hormone Specialist PhD Dr in the comments: you will find Dr analysis of your hormone levels and what to do next.

• Collect samples from the comfort of your home and post them to our lab.
• The test must be used within 12 months after the purchase date.
• The test kit includes a laboratory fee: no additional laboratory cost and tax.
• Customers are responsible for shipping their samples to the laboratory.

Testosterone is the primary male hormone; as men age, testosterone levels start to decrease. However, age is not the only reason for a decline in testosterone levels; overtraining can also reduce levels.

Understanding your levels of these key biomarkers and tracking them over time can help you manage symptoms you may be experiencing. 

Symptom Categories & Corresponding Symptoms - Male

Male Estrogen/Progesterone Deficiency Symptoms:

• Depressed
• Heart palpitations
• Hot flashes
• Neck or back pain
• Nights sweats and Sleeping difficulties

Male Estrogen Dominance/ Progesterone Deficiency Symptoms:

• Body temperature cold
• Irritable
• Libido decreased
• Prostate problems
• Urinary urge increased
• Urine flow decreased
• Weight gain breast or hips

Male Metabolic Syndrome Symptoms:

• Blood pressure high
• Cholesterol high
• Depressed
• Dizzy spells
• Erections decreased
• Irritable
• Muscle size decreased
• Muscle soreness
• Numbness -feet or hands
• Sugar carvings
• Triglycerides elevated
• Weight gain – waist

Male Low Androgens (DHEA/Testosterone Deficiency) Symptoms:

• Allergies
• Apathy
• Body temperature cold
• Bone loss
• Burned out feeling
• Depressed
• Erections decreased
• Fatigue – evening
• Fatigue – mental
• Fatigue – morning
• Flexibility decreased
• Forgetfulness
• Headaches
• Heart palpitations
• Hot flashes
• Irritable
• Joint pain
• Libido decreased
• Mental Sharpness decreased
• Muscle size decreased
• Muscle soreness
• Neck or back pain
• Night sweats
• Prostate problems
• Rapid ageing
• Ringing in ears
• Skin thinning
• Stamina decreased
• Stress
• Triglycerides elevated
• Urinary urge increased
• Urine flow decreased
• Weight gain- waist

Male High Androgens (DHEA/Testosterone Deficiency) Symptoms :

• Acne
• Aggressive behaviour
• Anxious
• Blood pressure high
• Hair or shin oily
• Irritable
• Nervous
• Sleeping difficulty
• Sugar carvings
• Weight gain – breast or hips

Male Low Cortisol Deficiency Symptoms:

• Allergies
• Apathy
• Blood pressure low
• Blood sugar loss
• Body temperature cold
• Burned out feeling
• Chemical sensitivity
• Depressed
• Dizzy spells
• Fatigue – evening
• Fatigue – mental
• Fatigue – morning
• Infertility
• Irritable
• Joint pain
• Mental Sharpness decreased
• Neck or back pain
• Pulse rate slow
• Stamina decreased
• Stress
• Sugar carvings
• Swelling or puffy eyes/face

Male High Cortisol Deficiency Symptoms:

•  Anxious
• Blood pressure high
• Body temperature cold
• Bones loss
• Depressed
• Erection decreased
• Forgetfulness
• Hot flashes
• Libido decreased
• Metal sharpness decreased
• Muscle size decreased
• Nervous
• Night sweats
• Rapid ageing
• Skin thinning
• Sleeping difficulty
• Stress
• Sugar carvings
• Triglycerides elevated
• Weight gain – waist

Male Hypometabolism:

• Anxious
• Body temperature cold
• Cholesterol high
• Constipation
• Depressed
• Dizzy spells
• Fatigue – evening
• Fatigue – mental
• Fatigue – morning
• Goitre
• Hair – dry or brittle
• Headaches
• Hearing lose
• Heart palpitations
• Hoarseness
• Infertility
• Joint pain
• Libido decreased
• Nails – breaking or brittle
• Pulse rate slow
• Ringing in ears
• Stamina decreased
• Sweating decreased
• Swelling or puffy eyes/face
• Triglycerides elevated

Testosterone and Sex Hormone Binding Globulin (SHBG) hormone imbalance:

Testosterone levels can also be either too high or too low. Testosterone in excess, often caused by ovarian cysts, leads to conditions such as excessive facial and body hair, acne, and oily skin and hair. Polycystic ovarian syndrome (PCOS) is thought to be caused, in part, by insulin resistance. On the other hand, too little testosterone is often caused by excessive stress, medications, contraceptives, and surgical removal of the ovaries. This leads to symptoms of androgen deficiency, including loss of libido, thinning skin, vaginal dryness, loss of bone and muscle mass, depression, and memory lapses. SHBG is a protein produced by the liver in response to exposure to any type of estrogen, whether produced naturally by the body, consumed as a synthetic oral contraceptive estrogen, estrogen therapy, or as foods or herbs (phytoestrogens). Released from the liver into the bloodstream, SHBG binds tightly to circulating estradiol and testosterone, preventing their rapid metabolism and clearance and limiting their bioavailability to tissues. SHBG gives a good index of the extent of the body’s overall exposure to estrogens. The SHBG level is also used to calculate free (unbound) testosterone levels when blood spot is used instead of saliva to measure sex hormones.

DHEA Hormone Imbalance:

 Mostly found in the circulation in its conjugated form, DHEA sulfate (DHEA-S) is a hormone produced by the adrenal glands, and levels generally reflect adrenal gland function. It is a precursor for the production of estrogens and testosterone and is, therefore, normally present in greater quantities than all the other steroid hormones. Its production is highest in the late teens to early 20s and declines gradually with age. Like cortisol, it is involved with immune function, and a balance between the two is essential. Low DHEA can result in reduced libido and general malaise, while high DHEA can have masculinising effects on women because it metabolises to androgens, including testosterone. Because of its conversion to estrogens and androgens, it is important to monitor levels of these hormones, as well as levels of DHEA, during supplementation.

Cortisol hormonal imbalance is an indicator of adrenal function and exposure to stressors. Under normal circumstances, adrenal cortisol production shows a diurnal variation and is highest early in the morning, soon after waking, falling to lower levels in the evening. Normal cortisol production shows a healthy ability to respond to stress. Low cortisol levels can indicate adrenal fatigue (a reduced ability to respond to stressors) and leave the body more vulnerable to poor blood sugar regulation and immune system dysfunction. Chronically high cortisol is a consequence of high, constant exposure to stressors. This has serious implications for long-term health, including an increased risk of cancer, osteoporosis, and possibly Alzheimer’s disease.

Free T4, free T3, TSH, and TPO hormone imbalance tests can indicate the presence of an imbalance in thyroid function, which can cause a wide variety of symptoms, including feeling cold all the time, low stamina, fatigue (particularly in the evening), depression, low sex drive, weight gain, and high cholesterol. Thyroid deficiency can also cause infertility, which is why these tests are included in the Female Fertility Profiles.

LH hormone imbalance tests are included in the Female Fertility Profile to give information on the possible presence of PCOS (elevated LH/FSH).

TSH – Thyroid Stimulating Hormone

 The pituitary produces TSH. TSH acts on the thyroid gland to stimulate the thyroid hormone T4 and T production3. Higher than normal TSH can indicate overproduction of or excessive supplementation with T4 and T3, negatively affecting the pituitary to reduce TSH production. Low TSH can also be caused by problems in the pituitary gland itself, which result in insufficient TSH being produced to stimulate the thyroid (secondary hypothyroidism).

Free T4- Thyroxine

The predominant hormone is produced by the thyroid gland. It is an inactive hormone converted to its active form, T3, within cells. Free T4 is the non-protein bound fraction of the T4 circulating in the blood, representing about 0.04% of the total circulating T4 available to tissues. Low TSH combined with low T4 levels indicates hyperthyroidism. High TSH and low T4 abdicate a thyroid gland disease, such as autoimmune thyroiditis (Hashimoto’s).

Total T4 – Thyroxine

Total T4 includes both free T4 and protein-bound T4 and, therefore, represents the thyroid gland’s capacity to synthesise, process, and release T4 into the bloodstream. In contrast, free T4 represents only the bioavailable circulating hormone and is not tightly complex with thyroid-binding globulin (TBG). Certain conditions, like oral estrogen usage or pregnancy, can

 cause total levels to change due to liver induction of TBG. This can result in no change in free T4 or lower bioavailable levels of free T4 even though total T4 increases.

Free T3 – Triiodothyronine

The active thyroid hormone regulates the metabolic activity of cells. Free T3 is the non-protein-bound fraction circulating in the blood, representing about 0.4% of the total circulating T3 available to tissues. Elevated T3 levels are seen in hyperthyroid patients, but levels can be normal in hypothyroid patients because it does not represent the intracellular conversion of T4 to T3, which comprises about 60% of all T3 formed in tissues.

TPO – Thyroid Peroxidase Antibodies

Thyroid peroxidase is an enzyme used by the thyroid gland in the manufacture of thyroid hormones by liberating iodine for attachment to tyrosine residues on thyroglobulin. In patients with autoimmune thyroiditis (predominantly Hashimoto’s disease), the body produces antibodies that attack the thyroid gland, and levels of these antibodies in the blood can diagnose this condition and indicate the extent of the disease.

Thyroglobulin

A protein rich in tyrosine and synthesised only in the thyroid gland. When bound to iodine, tyrosine residues in thyroglobulin become the source material for synthesising the thyroid hormones T3 and T4. When iodine levels are low, high levels of thyroglobulin can be found in the blood as iodine-poor thyroglobulin builds up and leaks from the thyroid into the bloodstream. Levels of thyroglobulin are an indicator of a person’s average iodine exposure over a period of weeks: the more significant the iodine exposure, the lower the thyroglobulin level. Elevated thyroglobulin, in the absence of more serious thyroid diseases such as thyroid cancer, which results in very high blood thyroglobulin levels, indicates low iodine status.

Hemoglobin A1c (HbA1c)

It is a glycated form of haemoglobin that results from the binding of haemoglobin in red blood cells to glucose in the bloodstream. Once the hemoglobin has bound to glucose, it remains glycated. Circulating red blood cells have a lifespan of 120 days; therefore the amount of HbA1c at any time point reflects the average exposure of red blood cells to glucose over the previous three months. It can, therefore, indicate impaired glucose tolerance even when occasional fasting plasma glucose measurements are normal.

High Sensitivity C-Reactive Protein (hs-CRP)

C-reactive protein (CRP) is an established marker of inflammation. It has recently been suggested to be an important contributor to the pro-inflammatory and pro-thrombotic elements of cardiovascular disease (CVD) risk.

Extremely high CRP levels are seen in acute inflammatory states, but the small elevations indicative of the pro-inflammatory and pro-thrombotic states implicated in the metabolic syndrome require high sensitivity assays and are thus referred to as hs-CRP levels.

Studies have shown correlations between elevated hs-CRP and increased risk of future heart attacks, ischemic stroke, and peripheral arterial disease. Overweight, obese, insulin-resistant, and diabetic individuals typically have elevated hs-CRP levels; elevations in hs-CRP levels have also been found to predict the development of diabetes—lifestyle changes such as aerobic exercise, weight loss, and smoking cessation lower hs-CRP levels. Levels below 3.0 mg/L are considered normal; 3.1—10 mg/L is elevated in the context of CVD risk, and above 10 mg/ L is very high, more likely indicating an acute inflammatory event due to infection or trauma. 

Vitamin D in Blood Spot

Vitamin D Deficiency – A Real Problem

Most people are familiar with vitamin D’s role in preventing rickets in children and helping the body absorb calcium from the diet.

Recently, research has shown that vitamin D is important in protecting the body from a wide range of diseases. Disorders linked with vitamin D deficiency include:

• Stroke
• Flu
• Cardiovascular disease
• Osteoporosis
• Osteomalacia
• Several forms of cancer
• Some autoimmune diseases, such as multiple Sclerosis
• Rheumatoid Arthritis
• Type I Diabetes & Type II Diabetes
• Breast and Colon Cancer (linked to Vitamin D Deficiency)
• Depression and even schizophrenia.

Vitamin D is a prohormone and not technically a vitamin: a vitamin is defined as a substance that is not made naturally by the body but must be supplied in the diet to maintain life processes. But in fact, we make most of our vitamin D by the action of ultraviolet light (sunlight) on the vitamin D originator found in our skin. As a result, we only get minimal amounts of vitamin D from our diet, although increasingly, it is added to foods eaten by children in an attempt to prevent rickets in the population.

A major cause of deficiency is not getting enough sun.

This happens because people don’t spend much time outdoors, women in particular often have much of their skin area covered for cultural reasons, and sunscreen also blocks the formation of vitamin D in the skin.

Testing for vitamin D is an important screening test, especially if you spend much of your time indoors or live in a colder climate. This blood spot test measures both the natural form of Vitamin D (D3) and D2, the form used in many supplements. So, testing can be used to monitor vitamin D supplementation to ensure you are getting the right amount for optimum health.

If you are experiencing any or a combination of those, it’s worth getting your hormone level imbalance checked using our comprehensive 30-panel Blood Spot hormone test for males.

This test will enable you to find out about your hormonal balance and if it is needed to see your doctor make a precise and accurate diagnosis.

This blood spot testing kit helps eliminate recurring doubts and fears about your feelings—a simple step of collecting your sample and sending it to us. 

How to Use