Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — PMDD and hormones

Inositol is a naturally occurring sugar alcohol found in foods such as beans, grains, nuts, and fresh produce. Beyond its well-established role in insulin signalling and PCOS management, inositol has been studied extensively for its effects on mood and mental health. Clinical trials have demonstrated benefits in panic disorder, obsessive-compulsive disorder, depression, premenstrual dysphoric disorder, and binge eating. This guide reviews the evidence, explains how inositol influences neurotransmitter pathways, covers dosing and safety considerations, and explains why laboratory testing is the most reliable way to determine whether inositol supplementation is appropriate for you.

Vitex agnus-castus — also known as chasteberry or chaste tree berry — is one of the most widely used botanical remedies for female hormone imbalance. Clinical research supports its use for reducing elevated prolactin, correcting luteal phase progesterone deficiency, alleviating PMS and PMDD symptoms, and managing some symptoms of the menopausal transition. This article reviews the evidence behind Vitex, explains the hormonal mechanisms through which it works, and outlines when it may be an appropriate botanical option for women with menstrual cycle disturbances.