Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — menopause transition

Explore the vital role of estrogen in perimenopause, its impact on mood, sleep, heart and bone health, and the latest research on hormone therapy options.

By Dr. Sherry LaBeck of ZRT Lab Perimenopause is the transition between a woman's reproductive years and menopause, characterized by a decline in estrogen levels, which can lead to physical and emotional symptoms. Understanding the role of estrogen during this phase is essential for managing symptoms and improving the quality of life for women going through this transition. What is Perimenopause? Perimenopause typically begins in a woman's 40s, though some may experience symptoms as early as their mid-30s, which is known as premature menopause. During this phase, the ovaries produce less estrogen until menstruation stops, marking the onset of menopause....

Perimenopause is far more than a collection of symptoms to manage — it is a critical window of opportunity to protect long-term cardiovascular, skeletal, and cognitive health. The hormonal fluctuations of this transition are directly linked to cardiovascular risk, making proactive action during perimenopause one of the most important investments a woman can make in her future health. This article outlines a practical three-step perimenopausal game plan covering hormone replacement, resistance training, and time-restricted eating — grounded in current research and designed to build the physiological reserves needed for a healthy postmenopause.

Heavy periods affect millions of women, yet the underlying causes are frequently misunderstood or left unaddressed. From oestrogen and progesterone imbalances to structural issues such as fibroids and adenomyosis, there are several well-established reasons why menstrual bleeding can become excessive. This article explains the physiology of the menstrual cycle, the most common causes of heavy periods, and how hormone testing can help identify what is driving your symptoms — so you can take informed steps towards better menstrual health.

In perimenopause, falling estradiol doesn’t just trigger hot flashes — it disrupts serotonin production, driving mood swings, brain fog and sleepless nights. Discover the hormonal science behind “the change” and how testing can help.