By Dr. Allison Smith, ZRT Laboratory Sex Hormone Binding Globulin (SHBG) is one of the most overlooked variables in hormone health. It directly controls how much testosterone is biologically active in your body — yet it rarely appears on standard blood panels. Whether you're dealing with symptoms of low testosterone, androgen excess, or unexplained hormonal imbalance, understanding SHBG is essential to getting the full picture. What is SHBG? SHBG is a protein produced primarily in the liver that binds tightly to testosterone — and to a lesser degree, oestradiol (E2) and dihydrotestosterone (DHT) — and carries them through the bloodstream....
Most of us know when something feels off — fatigue, weight gain, mood swings, poor sleep. But fewer people realise that a hormonal imbalance is often at the root. Learn how the endocrine system works, what throws it out of balance, and how at-home hormone testing can help you find answers.
Dr. Cobi Slater’s Ultimate Hormone Balancing Guidebook arrives at a moment when hormonal dysfunction has never been more widespread. Her central argument — that the real cause behind the plethora of symptoms plaguing modern adults can be linked to imbalances within the hormonal cascade — is backed by research-based evidence and practical, natural solutions. This review covers the book’s key chapters and explains why it remains an essential reference for anyone navigating hormone health.
Low libido in perimenopause is rarely just one thing — it’s a mosaic of hormonal, physical and lifestyle factors. From falling oestrogen and DHEA to thyroid dysfunction and metabolic syndrome, discover what’s really driving the loss of desire and how hormone testing can help.
DHEA and DHEA-S are the most abundant steroid hormones in the body and play a critical role in brain health, mood regulation, and cognitive function. This article explains the biochemical distinction between the two, how they act as neurosteroids, and why measuring DHEA-S is the gold standard for assessing adrenocortical activity.