Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — hippocampal function

Many women going through menopause notice changes in their ability to remember things — and this is not just in their heads. A small, seahorse-shaped structure in the brain called the hippocampus is highly dependent on estrogen for synaptic plasticity, memory formation and neuroprotection. In this article, Margaret Groves of ZRT Laboratory explains the science behind menopause-related memory changes, why estrogen receptor expression declines with age, and why the “window of opportunity” for hormone replacement is critical to preserving cognitive function.

DHEA and DHEA-S are the most abundant steroid hormones in the body and play a critical role in brain health, mood regulation, and cognitive function. This article explains the biochemical distinction between the two, how they act as neurosteroids, and why measuring DHEA-S is the gold standard for assessing adrenocortical activity.