Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — Healthy Stress Response

  By Nina Silberstain, BA The COVID-19 pandemic has only magnified what we already know: Working in health care can be stressful. A survey conducted by Mental Health America between June-September 2020 of 1,119 health care workers found that 93% were experiencing stress in addition to anxiety, frustration, exhaustion, burnout, and feeling overwhelmed. (1) Why Is Self-Care So Hard? Without a doubt, a large part of taking care of yourself is managing your stress levels. People attracted to the world of health care are often empathetic and caregivers by nature. Providing care can be rewarding but at the same time it...

Single nucleotide variations (SNVs) in the enzymes that metabolise estrogen can significantly alter breast cancer risk — in some cases by as much as 12-fold when multiple variants combine. In this detailed scientific overview, Jillian Harrington PhD of ZRT Laboratory explains how variations in CYP11A1, CYP19A1 (aromatase), CYP1B1, COMT and MnSOD affect the estrogen metabolism pathway, why catechol estrogens are dangerous, and how methylation testing can reveal individual vulnerability.

Dried urine testing is rapidly becoming the preferred method for neurotransmitter and hormone assessment — but collection timing is everything. In this clinical overview, Dr. Kate Placzek of ZRT Laboratory explains why a single morning urine sample cannot substitute for a 4-time-point collection, how neurotransmitters like epinephrine and norepinephrine follow distinct diurnal rhythms, and why interchanging the first and second morning voids can produce grossly inaccurate results.

As the days shorten and sunlight fades, four key hormonal systems come under pressure: vitamin D, serotonin, cortisol and melatonin. For those susceptible to Seasonal Affective Disorder (SAD), the disruption of these interconnected rhythms can trigger depression, fatigue, poor sleep and low mood. This article explains the science behind the SAD hormone pattern — and what you can do to support your body through the darker months.

Norepinephrine and epinephrine follow a distinct diurnal rhythm — rising through the morning, peaking in the afternoon, and falling at night. When this pattern is disrupted by chronic stress, the consequences ripple through every hormonal system in the body. Learn how the stress response works and how dried urine testing can reveal imbalances.