Blog — Cortisol Testing in Saliva

  In the realm of healthcare diagnostics, testing for various hormonal levels holds significant importance in understanding an individual's health. Traditionally, blood testing has been the norm for assessing hormone levels. However, the emergence of saliva testing has brought about a new dimension in evaluating hormones. Saliva testing provides a non-invasive and convenient method for individuals to collect their samples, allowing for a more accurate representation of bioavailable hormones – those readily accessible to target tissues. The Significance of Saliva Testing Saliva testing measures the unbound, bioavailable fraction of hormones, which stands in contrast to blood tests that often reflect...

Saliva testing is used for measuring hormones like cortisol, estrogen, progesterone, DHAES and testosterone, and its non-invasive collection asks patients to spit into a plastic tube. This sampling method allows patients to collect saliva at home at specific times, which is important for accurately measuring hormone levels. Why do we test hormones in saliva? Steroid hormones in the bloodstream are 95-99% bound to carrier proteins, and in this form are unavailable to target tissues. Saliva testing measures the amount of hormone available to target tissues – the bioavailable amount. For this reason, saliva testing better relates to specific symptoms of excess...

Hormone Test Providers should be aware that three different body fluids – saliva, blood or urine – can be used to assess adrenal gland function, and should know each method’s advantages and disadvantages, when deciding how to test patients. Inadequate or excessive production or disrupted circadian patterns of cortisol synthesis by the adrenal glands in response to stressors can eventually lead to imbalances in blood glucose levels, impaired immune response, as well as a host of different hormonal imbalances, all of which are associated with multiple adverse conditions and symptoms.    Saliva   Cortisol is synthesized by the adrenal glands and released into the bloodstream in...