Test ID: B-240 | Sample Type: Dried Blood Spot | Test Method: LC-MS/MS | Results: 3–5 Working Days | Laboratory: ZRT Lab — CLIA Certified | Report: Specialist Doctor Comment Included
Are Your Core Sex Hormones in Balance?
Oestrogen, progesterone, and testosterone don’t operate in isolation — they interact constantly, and an imbalance in one affects the others. Testing all three alongside SHBG gives you a complete picture of your hormonal ecosystem. If you recognise any of the following, this panel could reveal the root cause:
Symptoms of oestrogen (E2) imbalance:
- Bloating and water retention
- Acne or oily skin
- Low libido or vaginal dryness
- Hot flushes or night sweats
- Irritability, mood swings, or depression
- Poor concentration or memory lapses
- Decreased fertility
Symptoms of progesterone imbalance:
- Heavy, painful, or irregular periods
- Mood swings or PMS
- Tender or fibrocystic breasts
- Hot flushes
- Vaginal dryness or urinary issues
Symptoms of testosterone deficiency (affects women too):
- Loss of muscle mass or tone
- Persistent fatigue and low stamina
- Low libido or reduced sexual satisfaction
- Anxiety, low mood, or forgetfulness
- Dry skin or reduced body hair
- Fat deposits around the abdomen
Symptoms of SHBG imbalance:
- Excessive body hair or hirsutism (low SHBG)
- Acne, hair thinning, or irregular periods (low SHBG)
- Worsening testosterone deficiency symptoms despite normal total testosterone (high SHBG)
What This Test Measures
This panel tests four core sex hormone markers using highly accurate LC-MS/MS technology:
- Estradiol (E2) – The primary reproductive oestrogen; critical for cycle regulation, bone density, mood, and libido
- Progesterone (Pg) – Essential for cycle balance and fertility; counteracts oestrogen dominance
- Testosterone (T) – Vital for energy, muscle mass, libido, and mood in women
- SHBG (Sex Hormone Binding Globulin) – Determines how much oestrogen and testosterone is biologically available to your tissues; essential for interpreting total hormone levels accurately
How It Works
- Order your kit — delivered to your door
- Collect your sample at home — a simple finger-prick blood spot; no clinic or GP visit needed
- Post your sample to our CLIA-certified laboratory using the instructions provided
- Receive your results by email within 3–5 working days of the lab receiving your sample
What You Get With Your Results
Your personalised report includes:
- All four hormone levels displayed clearly in graphics and numbers
- A written interpretation by a Hormone Specialist PhD Doctor
- Guidance on what your results mean and what to do next
View a Sample Test Result Report
Who Is This Test For?
This test is suitable for women who want to:
- Assess their core sex hormone balance in a single, convenient test
- Investigate symptoms of hormonal imbalance, perimenopause, or PMS
- Understand why symptoms persist despite “normal” standard blood tests
- Monitor hormone levels during or after HRT or contraceptive changes
- Get a specialist interpretation of their oestrogen, progesterone, and testosterone together
Key Information
- Collect your sample from home and post to our lab — no clinic visit required
- Results delivered by email within 3–5 working days
- Laboratory fee included — no hidden costs or additional charges
- Valid for 12 months from the date of purchase
- Analysed by ZRT Laboratory — CLIA certified, with over 11 million tests performed
- Customers are responsible for posting their sample to the laboratory
Why We Use ZRT Laboratory
All testing is performed by ZRT Laboratory — a globally recognised, CLIA-certified diagnostic laboratory founded in 1998 by Dr. David Zava, PhD. ZRT has performed over 11 million tests and is trusted by healthcare professionals in 96+ countries.
- Pioneers of at-home dried blood spot (DBS) hormone testing
- Advanced LC-MS/MS and ICP-MS technology for clinical-grade accuracy
- Qualified for the CDC Hormone Standardization (HoSt) Program for testosterone and estradiol
- Personalised reference ranges based on age and sex
Through our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to women across the UK and Europe — from the comfort of home.