Test ID: B-243 | Sample Type: Dried Blood Spot | Test Method: LC-MS/MS | Results: 3–5 Working Days | Laboratory: ZRT Lab — CLIA Certified | Report: Specialist Doctor Comment Included
Are Complex, Overlapping Symptoms Leaving You Without Answers?
Thyroid and sex hormones are deeply interconnected in men — thyroid dysfunction can suppress testosterone, raise SHBG, and worsen andropause symptoms. Many men are treated for low testosterone when the root cause is actually thyroid dysfunction. If you recognise any of the following, this comprehensive 14-marker panel could finally give you the full picture:
- Persistent fatigue or exhaustion that doesn’t improve with rest
- Low libido or erectile dysfunction
- Loss of muscle mass or increased body fat
- Mood swings, depression, or anxiety
- Brain fog, poor concentration, or increased forgetfulness
- Sleep disturbances or insomnia
- Hot flushes or night sweats (andropause symptoms)
- Unexplained weight gain or slow metabolism
- Hair thinning or loss
- Decreased stamina or physical performance
- Cold intolerance or low body temperature
- High cholesterol, elevated triglycerides, or heart palpitations
- Bone loss or decreased muscle size
- Fertility concerns
Why Test Hormones and Thyroid Together?
A standard GP test typically only checks total testosterone and TSH separately — missing the complex interplay between these systems. This panel measures 14 markers across sex hormones, adrenal function, and a full thyroid panel, giving you and your doctor a complete clinical picture and avoiding misdiagnosis.
What This Test Measures
Sex Hormones & Adrenal Markers (8)
- Estrone (E1) – An oestrogen present in men; elevated levels are linked to fat gain and hormonal imbalance
- Estradiol (E2) – The primary oestrogen; men need balanced E2 for bone density and cardiovascular health, but excess causes low libido and gynaecomastia
- Estriol (E3) – A weaker oestrogen that helps assess overall oestrogen load in men
- Progesterone (Pg) – Supports testosterone production and counteracts oestrogen dominance in men
- Testosterone (T) – The primary male sex hormone; critical for energy, muscle mass, libido, mood, and metabolic health
- DHEA-S (DS) – An adrenal precursor hormone that declines with age; linked to vitality, immune function, and testosterone production
- Cortisol (C) – The stress hormone; chronically elevated cortisol directly suppresses testosterone production
- SHBG – Regulates how much testosterone is biologically available; high SHBG causes low-T symptoms even when total testosterone appears normal
Full Thyroid Panel (6)
- TSH – The primary screening marker for thyroid function
- Free T3 (fT3) – The active thyroid hormone; low fT3 is linked to fatigue, weight gain, and depression
- Free T4 (fT4) – The storage thyroid hormone converted to T3; key for assessing conversion issues
- Total T4 (TT4) – Measures total thyroxine including protein-bound hormone
- TPO Antibodies (TPOab) – Elevated levels indicate autoimmune thyroid disease (Hashimoto’s thyroiditis)
- Thyroglobulin (Tgbn) – A marker for thyroid tissue health and iodine-related dysfunction
How It Works
- Order your kit — delivered to your door
- Collect your sample at home — a simple finger-prick blood spot; no clinic or GP visit needed
- Post your sample to our CLIA-certified laboratory using the instructions provided
- Receive your results by email within 3–5 working days of the lab receiving your sample
What You Get With Your Results
Your personalised report includes:
- All 14 markers displayed clearly in graphics and numbers
- A written interpretation by a Hormone Specialist PhD Doctor
- Guidance on what your results mean and what to do next
View a Sample Test Result Report
Who Is This Test For?
This test is suitable for men who want to:
- Investigate complex or overlapping symptoms involving both hormones and thyroid
- Go beyond a basic testosterone or TSH test and get a truly comprehensive picture
- Screen for Hashimoto’s, andropause, adrenal fatigue, or oestrogen dominance
- Understand why symptoms persist despite “normal” standard blood tests
- Monitor multiple hormone systems during or after TRT, thyroid medication, or other treatment
Key Information
- Collect your sample from home and post to our lab — no clinic visit required
- Results delivered by email within 3–5 working days
- Laboratory fee included — no hidden costs or additional charges
- Valid for 12 months from the date of purchase
- Analysed by ZRT Laboratory — CLIA certified, using LC-MS/MS technology with over 11 million tests performed
- Customers are responsible for posting their sample to the laboratory
Why We Use ZRT Laboratory
All tests are analysed by ZRT Laboratory — a globally recognised, CLIA-certified laboratory founded in 1998 by Dr David Zava, PhD. Trusted by healthcare professionals in over 96 countries, ZRT uses advanced LC-MS/MS and ICP-MS technology to deliver accurate, research-backed results with personalised reference ranges — from the comfort of home.
