Test ID: B-242 | Sample Type: Dried Blood Spot | Test Method: LC-MS/MS | Results: 3–5 Working Days | Laboratory: ZRT Lab — CLIA Certified | Report: Specialist Doctor Comment Included
Could a Hormone Imbalance Be Behind Your Fatigue, Low Libido, or Mood Changes?
Male hormonal health is rarely a single-hormone issue — testosterone, cortisol, DHEA-S, oestrogens, and SHBG all interact in a complex system. When one is off, the whole system is affected. Symptoms are frequently dismissed as stress or ageing when the root cause may be hormonal. If you recognise any of the following, this comprehensive panel could reveal what’s really going on:
- Low libido or sexual dysfunction
- Persistent fatigue and low energy despite adequate sleep
- Loss of muscle mass or increased body fat, especially around the abdomen
- Mood swings, depression, irritability, or anxiety
- Brain fog, poor concentration, or memory lapses
- Sleep disturbances or insomnia
- Hot flushes or night sweats (andropause symptoms)
- Decreased stamina or physical performance
- Slow metabolism or unexplained weight gain
- Burnout or chronic stress
What This Test Measures
This panel tests eight essential hormones using highly accurate LC-MS/MS technology:
- Estrone (E1) – An oestrogen that plays a role in male bone density and cardiovascular health; elevated levels can indicate aromatisation issues
- Estradiol (E2) – The primary oestrogen; elevated levels in men are linked to low libido, fat gain, and gynaecomastia
- Estriol (E3) – A weaker oestrogen that helps assess overall oestrogen balance
- Progesterone (Pg) – Supports testosterone production and counteracts oestrogen dominance in men
- Testosterone (T) – The primary male sex hormone; critical for energy, muscle mass, libido, mood, and metabolic health
- DHEA-S (DS) – An adrenal hormone that declines with age; linked to vitality, immune function, and stress resilience
- Cortisol (C) – The stress hormone; chronically elevated cortisol directly suppresses testosterone production
- SHBG (Sex Hormone Binding Globulin) – Determines how much testosterone is biologically available; high SHBG can cause testosterone deficiency symptoms even when total testosterone appears normal
Why a Comprehensive Panel Matters
A standard GP testosterone test only measures total testosterone — which can miss significant hormonal dysfunction. This panel gives you a complete picture of your hormonal ecosystem, including how stress hormones and oestrogen are affecting your testosterone availability. This enables far more informed conversations with your GP or specialist.
How It Works
- Order your kit — delivered to your door
- Collect your sample at home — a simple finger-prick blood spot; no clinic or GP visit needed
- Post your sample to our CLIA-certified laboratory using the instructions provided
- Receive your results by email within 3–5 working days of the lab receiving your sample
What You Get With Your Results
Your personalised report includes:
- All eight hormone levels displayed clearly in graphics and numbers
- A written interpretation by a Hormone Specialist PhD Doctor
- Guidance on what your results mean and what to do next
View a Sample Test Result Report
Who Is This Test For?
This test is suitable for men who want to:
- Investigate symptoms of low testosterone, andropause, or adrenal fatigue
- Understand why they feel unwell despite normal standard blood tests
- Assess how stress hormones and oestrogen are affecting their testosterone
- Monitor hormone levels during or after TRT or other hormone therapy
- Take a proactive, data-driven approach to their hormonal health
Key Information
- Collect your sample from home and post to our lab — no clinic visit required
- Results delivered by email within 3–5 working days
- Laboratory fee included — no hidden costs or additional charges
- Valid for 12 months from the date of purchase
- Analysed by ZRT Laboratory — CLIA certified, using LC-MS/MS technology with over 11 million tests performed
- Customers are responsible for posting their sample to the laboratory
Why We Use ZRT Laboratory
All testing is performed by ZRT Laboratory — a globally recognised, CLIA-certified diagnostic laboratory founded in 1998 by Dr. David Zava, PhD. ZRT has performed over 11 million tests and is trusted by healthcare professionals in 96+ countries.
- Pioneers of at-home dried blood spot (DBS) hormone testing
- Advanced LC-MS/MS and ICP-MS technology for clinical-grade accuracy
- Qualified for the CDC Hormone Standardization (HoSt) Program for testosterone and estradiol
- Personalised reference ranges based on age and sex
Through our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to men across the UK and Europe — from the comfort of home.
