Blog — Topical Testosterone

Male Menopause (Andropause) and Treatment

Posted by Ben White on

As men age, they may experience a decline in testosterone levels which can lead to a range of symptoms commonly referred to as male menopause or andropause. This condition is not as well-known as female menopause, but it can have a significant impact on a man's quality of life. Fortunately, there are treatments available, including hormone testing, to help alleviate the symptoms associated with male menopause. What is Male Menopause? Male menopause is a condition caused by a decline in testosterone levels as a man ages. Testosterone is the primary male sex hormone and is responsible for many of the...

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Topical Testosterone & the U-Shaped Curve

Posted by Ben White on

By Dr Allison Smith, ZRT Laboratory The testicles of a man in his 20s are known to contribute about 5-10mg of testosterone per 24-hour day and levels of total testosterone in the venous blood with that amount are observed to yield roughly 300-1200 ng/dL in the morning at the diurnal peak. Testosterone, whether endogenous or given exogenously, negatively feeds back on the hypothalamus, limiting GnRH and thus LH and FSH from the pituitary. A man taking supraphysiological doses of testosterone can expect to have very low or undetectable levels of LH and FSH in the serum. What happens when the...

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