Blog — #Progesterone
Perimenopause, Symptoms and Treatment
Posted by Ben White on
Perimenopause, also known as the menopausal transition, is a natural and normal part of a woman's life. It refers to the years leading up to menopause, which is defined as the point at which a woman has not had a menstrual period for 12 consecutive months. Perimenopause typically begins in a woman's 40s but can start as early as the mid-30s. During perimenopause, the body's production of estrogen and progesterone, two hormones essential to a woman's reproductive system, begins to decline. This decline can cause a range of symptoms, including hot flashes, night sweats, mood swings, sleep disturbances, vaginal dryness,...
Menopause: Your Most Common Questions Answered
Posted by Ben White on
By ZRT Laboratory Consultants. Menopause can be a confusing time for many women and their families, and as a society we tend to steer away from having open, honest conversations about this very important transition in a woman’s life. At ZRT, we aim to change that and equip all women with the tools and resources necessary to maintain optimal health during their menopause transition and after. In this post, ZRT’s Clinical Consultants tackle the most commonly asked questions and misunderstandings about menopause from patients. What Age Does Menopause Occur? Menopause is defined as the natural absence of menstrual periods for...
Topical Progesterone, Not Synthetic Progestins or Oral Progesterone, Should Be Considered as a Companion for Estradiol Replacement Therapy
Posted by Ben White on
By Dr.David Zava, ZRT Laboratory In 2002 several large-scale clinical studies were published on the risks of breast cancer in postmenopausal women using conventional FDA-approved hormone therapy. These were the Women’s Health Initiative (WHI) and Million Women’s studies of women using FDA-approved estrogens and progestogens in the United States and Great Britain, respectively [1,2]. Both studies came to the same conclusion – that estrogen therapy, mostly in the form of oral conjugated equine estrogens, by itself did not significantly increase the risk of breast cancer and, to the surprise of many, was associated with a lower risk. However, when estrogen was...
The Younger, Sexy Me…nopause!
Posted by Ben White on
By Margaret Grove, ZRT Laboratory. Sometimes you look back and wonder where all the time went. Let’s see - in my twenties, the younger, sexier me had been to University and embarked on a career in medical research, and I’d been very active in my leisure time – including hiking and skiing every year in the Alps. I was too invested in my career and hobbies to have children and wanted to put that off until the right time. In my thirties, I eventually realized it was time to start a family before it was too late. At age 35...
Topical Delivery of Sex Steroid Hormones and Distribution in Different Body Fluids
Posted by Ben White on
By David Zava, ZRT Laboratory Delivery of the bioidentical hormones estradiol (E2), progesterone (Pg), and testosterone (T) through the skin as a cream or gel (topically) has become a mainstay of bioidentical hormone replacement therapy (BHRT) for women and men. A plethora of FDA-approved pharmaceuticals, compounded, and even over-the-counter topical BHRT products are available. The popularity of these products lies not only in their ease of use but in proven clinical efficacy [1-5] in treating hormonal deficiencies mostly brought on by ageing of the female (menopause) and male (andropause) reproductive systems. Dosing for Optimal Clinical Benefit Over the past 30 or so...