Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — DIM supplements

Single nucleotide variations (SNVs) in the enzymes that metabolise estrogen can significantly alter breast cancer risk — in some cases by as much as 12-fold when multiple variants combine. In this detailed scientific overview, Jillian Harrington PhD of ZRT Laboratory explains how variations in CYP11A1, CYP19A1 (aromatase), CYP1B1, COMT and MnSOD affect the estrogen metabolism pathway, why catechol estrogens are dangerous, and how methylation testing can reveal individual vulnerability.

Weight loss failure is rarely just about willpower or diet — hormones are almost always involved. In this Q&A, Dr. Alyssa Burns-Hill of ZRT Laboratory tackles the most common questions from people struggling to lose weight despite their best efforts: from thyroid interference by the contraceptive pill and stress-driven cortisol cravings, to estrogen-reducing supplements, natural progesterone for menopause, and why 5-HTP can be a game-changer for mood, sleep and comfort eating.