Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — Breast Cancer Risk

By Sherry LaBeck, ND. ZRT Laboratory. It is highly likely that women aged 60 to 90 have vivid memories of the astonishing healthcare news from 2002 when the Women's Health Initiative (WHI), a comprehensive long-term national health study, was abruptly terminated earlier than expected. The initial trial results sent shockwaves through the medical community and had a profound impact on the lives of numerous women. Furthermore, this news fundamentally transformed the perception of routine menopausal hormone replacement prescriptions for years to follow. The WHI was launched in 1991 as a 15-year trial, one of the largest women’s health studies in the...

Single nucleotide variations (SNVs) in the enzymes that metabolise estrogen can significantly alter breast cancer risk — in some cases by as much as 12-fold when multiple variants combine. In this detailed scientific overview, Jillian Harrington PhD of ZRT Laboratory explains how variations in CYP11A1, CYP19A1 (aromatase), CYP1B1, COMT and MnSOD affect the estrogen metabolism pathway, why catechol estrogens are dangerous, and how methylation testing can reveal individual vulnerability.

One in eight women will be diagnosed with breast cancer in their lifetime. But many risk factors are modifiable — including hormone imbalance and excess weight. Discover the two most important actions women can take to reduce breast cancer risk, and how hormone testing can help identify hidden imbalances before they become a problem.

The latest research confirms what Dr. John Lee and Dr. David Zava argued decades ago: maintaining healthy progesterone levels in proper balance with oestrogen is one of the most powerful tools women have for preventing and recovering from breast cancer. This article outlines seven practical steps to restore hormone balance and reduce breast cancer risk.

A landmark study published in Nature confirmed what Dr. John Lee and Dr. David Zava argued over a decade ago: natural progesterone — unlike synthetic progestins — can slow or even shrink ER+/PR+ breast cancer tumours. This article explains the receptor science behind the findings and what it means for women’s hormone health.