Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — advanced endocrine testing

When sex hormone test results show both oestradiol (E2) and progesterone (Pg) within normal ranges, yet symptoms persist, the Pg/E2 ratio provides a critical additional layer of clinical insight. A low ratio points to oestrogen dominance; a high ratio to progesterone dominance — each requiring a different therapeutic response. This article explains how the ratio is calculated, when it is clinically relevant, and how a real-world case illustrates its practical value.

Millions of people struggle with weight gain, fatigue and low mood despite being told their thyroid test results are “normal.” The problem is that a standard TSH test alone cannot identify the full range of factors that suppress thyroid function — from oestrogen dominance and elevated cortisol to iodine deficiency, selenium deficiency, heavy metal toxicity and xenoestrogen burden. This article explains what those hidden saboteurs are and how targeted testing can help identify them.

Melatonin is far more than a sleep supplement — it is a master regulator of the body’s circadian rhythm, a potent antioxidant, and a key signal for cell repair and gene transcription. Understanding how melatonin is produced, what its daily curve looks like, and how it can be accurately measured through first-morning urinary MT6s testing is essential for anyone investigating sleep disturbances, fatigue or hormonal imbalance.