New Research on Vitamin D Using Dried Blood Spot Testing

Posted by Ben White on

By Margaret N Groves, M.Phil, ELS

Two vitamin D studies were published recently, both utilising ZRT's testing in dried blood spots.

Dried blood spot samples are well suited for research applications because they are equivalent to serum but have the advantage of the ease of sample collection, shipping, and storage, which doesn’t require any refrigeration or biohazard labeling. Also, samples are easily identified by details that can simply be written on the outside flap of the collection cards, which require minimal freezer space for long-term storage of samples.

Here are brief summaries of each study:

Wakayo T, Belachew T, Vatanparast H, Whiting SJ. Vitamin D Deficiency and Its Predictors in a Country with Thirteen Months of Sunshine: The Case of School Children in Central Ethiopia. PLoS ONE 2015;10(3):e0120963.

In this study, vitamin D levels were tested in schoolchildren living in the sunny climate of Ethiopia.  Vitamin D deficiency, defined as 25-hydroxyvitamin D levels <50 nmol/L (equivalent to <20 ng/mL) was significantly more prevalent in children living in an urban environment (61.8%) compared with those in a rural setting (21.2%). Significant predictors of vitamin D deficiency in this study included body fatness, having a TV/computer at home, maternal education, and socioeconomic status. This study highlights lifestyle factors that can predispose people to vitamin D deficiency even in countries with high sun exposure. See full article.

Kerr DCR, Zava DT, Piper WT, Saturn SR, Frei B, Gombart AF. Associations Between Vitamin D Levels and Depressive Symptoms in Healthy Young Adult Women. Psych Res March 2015 [in press].

This study investigated the relationship between vitamin D sufficiency and depression. One hundred eighty healthy young women completed surveys to assess depressive symptoms at baseline and then once a week for 4 weeks, and serum vitamin D levels were determined at baseline and 4 weeks.  A high rate of vitamin D insufficiency, defined as levels <30 ng/mL, was seen, occurring in 42% and 46% of the women at baseline and week 4, respectively.  Lower vitamin D levels were related to clinically significant depressive symptoms. Purchase full article.

Related Tests

Vitamin D 25-oh total (Testing Vitamin D2 & D3)



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