Elite Female Saliva Hormone Profile (LCMS) | 8 Markers

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Elite Female Saliva Hormone Profile

Want a Broader View of Your Hormones, Sleep and Energy?

Changes in your periods, mood, energy, sleep or libido can be difficult to understand—especially when several symptoms occur together.

The Elite Female Saliva Hormone Profile measures three forms of oestrogen alongside progesterone, testosterone and DHEAS. It also compares your cortisol level upon waking with your level before bed.

This helps answer two practical questions:

How do my measured sex hormone levels compare with the laboratory ranges?

How does my cortisol level differ between morning and bedtime?

Your report presents eight results with reference ranges, visual graphs and hormone-specialist laboratory comments. These comments explain the findings and suggest useful next steps to consider.

  • Eight results from two saliva samples
  • Seven different hormones, with cortisol measured twice
  • Broader assessment of estrone, estradiol and estriol
  • Morning-to-bedtime cortisol comparison
  • Collect at home without needles or a clinic appointment
  • Hormone-specialist interpretation included
  • Laboratory analysis included
  • Normally reported within 3–5 working days after the laboratory receives your samples

Is This Test Right for Me?

This profile may be suitable if you want a broad female hormone assessment and are experiencing concerns such as:

  • Irregular periods or changes in your usual cycle
  • PMS, including mood changes, bloating or breast tenderness
  • Perimenopausal or menopausal symptoms
  • Reduced libido or changes in sexual wellbeing
  • Persistent tiredness or low energy
  • Poor sleep, night waking or difficulty winding down
  • Mood changes, irritability or difficulty concentrating
  • Changes in wellbeing during periods of sustained stress

It may also be useful if you want:

  • All three main oestrogens measured separately
  • Morning and bedtime cortisol included with your sex hormone results
  • A baseline for comparison with future tests
  • Results to discuss with a healthcare professional
  • Laboratory information to support a review of hormone treatment, where appropriate

These symptoms can have several possible causes. The test measures the hormones listed below; it does not establish one definitive explanation for every symptom.

What Will My Results Help Me Understand?

1. See Your Three Oestrogen Results

The profile measures estrone, estradiol and estriol separately.

Benefit: You receive a broader oestrogen assessment than a profile measuring estradiol alone. Your specialist can consider the three results alongside your age, menstrual stage, symptoms and hormone use.

2. Review Other Key Sex Hormones

The test also measures progesterone, testosterone and DHEAS.

Benefit: You can see how each measured hormone compares with the relevant laboratory range, giving you more information to discuss when reviewing menstrual, menopausal or sexual-wellbeing concerns.

3. Compare Morning and Bedtime Cortisol

Cortisol is measured upon waking and again before bed.

Benefit: The two results show whether your cortisol level changes between the beginning and end of your waking day. This may be useful when discussing morning tiredness, difficulty winding down, sleep or energy.

This is a two-point comparison. It does not provide the complete daily pattern shown by a four-point cortisol profile.

4. Decide What to Do Next

Your results are accompanied by hormone-specialist laboratory comments.

Benefit: You receive an explanation of the findings rather than a set of unexplained numbers. Depending on your results and the information provided on your requisition form, the comments may highlight:

  • Results that deserve further discussion
  • Relevant symptoms or treatment information
  • Practical areas to review with your healthcare professional
  • Whether additional testing may provide useful information
  • Findings that may be suitable for future comparison

What Will My Report Include?

Your ZRT Laboratory report includes:

  • Eight individual hormone results
  • Laboratory reference ranges
  • Visual graphs showing where your results fall
  • Clear indicators for results outside the applicable range
  • Your recorded collection dates and times
  • Relevant medicines and hormone treatments reported on your form
  • Your menstrual status and reported symptoms, where applicable
  • Individualised hormone-specialist laboratory comments
  • Suggested considerations or next steps based on the reported findings

The specialist interpretation is included within your ZRT Laboratory report. There is no separate Hormone Lab UK specialist report.

Providing complete information about your symptoms, menstrual status, medicines, supplements and hormone treatments helps the laboratory interpret your results in the appropriate context.

What Does the Test Measure?

Result What it adds to your assessment
Estrone (E1) Extends the oestrogen assessment beyond estradiol alone
Estradiol (E2) Provides a key oestrogen measurement to consider alongside your life stage and symptoms
Estriol (E3) Completes the three-oestrogen assessment
Progesterone Provides information about progesterone levels when collected at the appropriate stage of the cycle
Testosterone Measures an androgen relevant to female sexual and physical wellbeing
DHEAS Measures an adrenal androgen involved in the production of other sex hormones
Morning cortisol Shows your cortisol level at the beginning of your waking day
Bedtime cortisol Allows comparison with your morning cortisol result

Saliva testing measures the unbound fraction of these hormones present in the samples. Saliva and blood tests measure hormones differently, so their results and reference ranges should not be used interchangeably.

Test Details

Test ID: S-146
Test panel: LCMS Hormones 7 with 2-Point Cortisol
Sample type: Saliva
Results reported: 8
Different hormones measured: 7
Samples required: 2 — upon waking and before bed
Testing method: LC-MS/MS
Laboratory: ZRT Laboratory — CLIA-certified
Hormone specialist interpretation: Included within the laboratory report
Suitable for: Adults and children able to provide the required saliva volume
Collection: At home — no clinic visit required
Laboratory reporting time: Normally 3–5 working days after the laboratory receives your samples
Kit validity: Use within 12 months of purchase

What Is Included?

Your purchase includes:

  • At-home saliva collection kit
  • One large morning collection tube
  • One small bedtime collection tube
  • Test Requisition Form
  • Step-by-step collection instructions
  • Laboratory analysis of eight results
  • Reference-range comparisons
  • Visual result graphs
  • Individualised hormone-specialist laboratory comments
  • Suggested next steps or considerations
  • Digital ZRT Laboratory report
  • Laboratory analysis fee

Return postage to the laboratory is arranged and paid for separately by the customer.

How It Works

1. Choose Your Collection Day

Follow the menstrual-cycle schedule below and any treatment-specific instructions that apply to you.

2. Collect Your Morning Sample

Begin collecting into the large tube within 30 minutes of waking.

3. Collect Your Bedtime Sample

Collect into the small tube before bed on the same day. Follow the food, drink and toothbrushing restrictions in the supplied instructions.

4. Send Your Samples

Complete the Test Requisition Form and return both labelled samples using the packaging and shipping instructions provided.

5. Receive Your Explained Results

Your report is normally issued by email within 3–5 working days after the laboratory receives your samples.

Kit delivery and return-postage time are separate from this laboratory reporting period.

When Should I Collect My Samples?

For women testing reproductive hormones, use the following collection schedule:

Your cycle or situation Collection day
Regular cycle lasting 23–26 days Day 17, 18 or 19
Regular cycle lasting 27–30 days Day 21, 22 or 23
Regular cycle lasting 31–34 days Day 25, 26 or 27
Shorter or longer regular cycle 5–7 days before your next expected period
Infrequent or unpredictable periods Any non-bleeding day
No menstrual periods Any day, following treatment-timing instructions where applicable
Children Any day
Using hormone treatment Follow the treatment-specific collection instructions

Day 1 is the first day of menstrual flow, not spotting. Collect both samples on the same chosen day.

Which Female Hormone Test Should I Choose?

What do you want to understand? Suggested test
Estradiol, progesterone, testosterone, DHEAS and one morning cortisol result Female Saliva Hormone Profile I
All three oestrogens plus progesterone, testosterone, DHEAS and one morning cortisol result Female Saliva Hormone Profile III
The same seven hormones, with cortisol compared upon waking and before bed Elite Female Saliva Hormone Profile
All three oestrogens plus a complete four-point daily cortisol profile Advanced Female Saliva Hormone Profile

Choose the Elite profile if you want a broad three-oestrogen assessment and a simple morning-to-bedtime cortisol comparison.

If cortisol changes throughout the entire day are your main concern, a four-point cortisol profile may provide more relevant information.

Preparing for Your Test

To help produce usable samples:

  • Avoid anti-ageing or anti-wrinkle facial creams and biotin supplements for three days before collection.
  • Record all medicines, supplements and hormone treatments on your Test Requisition Form.
  • Collect the morning sample within 30 minutes of waking.
  • Do not eat, drink anything other than water or brush your teeth before the morning sample.
  • Avoid food, drinks other than water and toothbrushing for two hours before the bedtime sample.
  • Rinse your mouth with water and wait five minutes before collecting.
  • Fill each required tube at least halfway, excluding bubbles.
  • Label both tubes with your name, collection date and collection time.
  • Freeze the samples if they will not be posted within 24 hours.

If you use hormone treatment, corticosteroids, troches or hormones dissolved under the tongue, follow the treatment-specific instructions before collecting. An alternative sample type may be recommended for some treatments.

Read the full Saliva Collection Instructions.

Frequently Asked Questions

What Are the Eight Results?

Estrone, estradiol, estriol, progesterone, testosterone, DHEAS, morning cortisol and bedtime cortisol.

These represent seven different hormones, with cortisol measured twice.

How Many Samples Do I Need to Collect?

Two samples on the same day: one in the large tube upon waking and one in a small tube before bed.

Follow the S-146 schedule in your instructions. Additional tubes supplied in the collection kit are not required for this profile.

Does the Report Include Specialist Interpretation?

Yes. Hormone-specialist laboratory comments are included within your ZRT Laboratory report.

The comments explain relevant findings and may suggest points to discuss, practical areas to review or further investigations to consider. They are not a separate medical consultation.

Does This Test Show My Complete Daily Cortisol Pattern?

No. It compares cortisol upon waking and before bed.

If you want to see how cortisol changes at four points from morning to bedtime, choose a profile containing a four-point cortisol assessment.

How Does This Differ From Female Saliva Hormone Profile III?

Both profiles measure estrone, estradiol, estriol, progesterone, testosterone, DHEAS and morning cortisol.

The Elite profile also includes a bedtime cortisol result, allowing a morning-to-bedtime comparison.

Can I Use This Test After Menopause?

Yes. If you no longer have periods, you can collect on any day. Follow the treatment-specific instructions if you use HRT or another hormone treatment.

Can I Use This Test While Taking HRT?

It may be suitable depending on the treatment and how it is administered. Continue prescribed treatment as directed, record all hormone use on your requisition form and follow the treatment-specific collection instructions.

An alternative sample type may be recommended for troches or hormones taken under the tongue.

What If My Periods Are Irregular?

If your periods are infrequent or unpredictable, collect on any non-bleeding day. Record your menstrual history on the requisition form to provide context for your results.

Is the Test Suitable for Children?

Yes, provided the child can supply the required amount of saliva. Include their age, symptoms and reason for testing so the results can be considered appropriately.

How Quickly Will I Receive My Results?

The laboratory normally reports within 3–5 working days after receiving your samples. Kit delivery and return-postage times are additional.

Does the Price Include Laboratory Analysis?

Yes. The collection kit, laboratory analysis, digital report and hormone-specialist laboratory comments are included.

You are responsible for arranging and paying for return postage to the laboratory.

How Long Can I Keep the Kit?

Use the kit within 12 months of purchase.

Not Sure Whether This Is the Right Test?

Email info@hormonelab.co.uk with your age, main symptoms, menstrual status, medicines and current treatments. Our team will forward your enquiry to our specialist doctors and respond with a suggested testing option within 24 hours.