Test ID: S-124
LCMS Hormones 5 Male Saliva Hormone Test for men that measures testosterone, estradiol, DHEAS, progesterone, and cortisol. See how stress, sleep, libido, mood, and energy relate to your hormones. Fast lab results with expert commentary.
What this test measures
- Testosterone (T): libido, muscle, strength, bone density, vitality
- Estradiol (E2): cardiovascular, bone, prostate, mood balance
- DHEAS (DS): adrenal output, precursor to sex hormones
- Progesterone (Pg): balances estrogens, neurocalming effects
- Cortisol (C): stress response, metabolism, sleep–wake rhythm
- How and when to Collect your saliva samples: Saliva Testing Instructions
- Click to see >> Sample Saliva Test Result Report
Why choose this test
- Comprehensive 5-marker profile for male hormonal health
- Accurate, bioavailable levels via saliva (time-specific collection)
- Home collection. No clinic, no needles
- Results in 3–5 working days after the lab receives your sample
- PhD Hormone Specialist comments with next-step recommendations
- Clear visuals + numbers for easy interpretation
- All-inclusive price (lab fee included). You cover return postage
- 12-month kit validity. Use when convenient
- For adults and teens under clinical guidance
Who it's for
Men with any of the following: low energy, reduced libido, mood changes, poor sleep, belly-fat gain, training burnout, plateaued muscle gains, hot flushes/night sweats, brain fog, or suspected adrenal issues.
How it works
- Order your kit.
- Collect saliva per timing guide.
- Post your sample to the lab.
- Receive your report and specialist analysis in 3–5 working days.
What you receive
- Graphical and numeric hormone levels
- PhD specialist interpretation and tailored next steps
- Guidance on retesting and lifestyle or clinical options
Why saliva testing
- Reflects bioactive (unbound) hormones
- Supports timed collections (e.g., morning cortisol)
- Convenient for monitoring therapy and training load
Shipping and privacy
- Lab fee included; you handle shipping to the lab
- Confidential processing and results portal access
FAQ
What hormones are included?
Testosterone, estradiol (E2), DHEAS, progesterone, and cortisol.
How accurate is saliva testing?
It measures bioavailable hormones and is well suited for timed collections and monitoring changes over time.
How fast are results?
3–5 working days after your sample reaches the lab.
Do I need to stop supplements or HRT?
Follow the kit's timing guide. If on prescription hormones, ask your clinician about test timing.
When should I collect samples?
Morning collections are typical; follow kit instructions for any additional time points.
Is this useful for athletes or overtraining checks?
Yes. Testosterone, DHEAS, and cortisol patterns can flag under-recovery.
Will someone explain my results?
Yes. A PhD Hormone Specialist adds comments and actionable guidance.
Any hidden fees?
No. Lab analysis is included. You only pay return postage.
Who shouldn't use this kit?
If you have an acute medical issue or require urgent testing, seek in-person care first.
How often should I retest?
Every 8–12 weeks when changing training, lifestyle, or therapy; otherwise as advised by your clinician.
What's the difference between each testing method?
Enzyme Immunoassay (EIA) – antibody/antigen-based technology with moderate specificity and sensitivity, low cost, not ideal for complex hormone analysis. Utilized for over a half century. Typically used on 96-well plate hormone assays.
Electrochemiluminescence (ECLIA) – antibody/antigen-based technology with improved specificity and sensitivity, low cost, works well for testing endogenous steroid hormones, but not for testing topical hormone therapies (gross underestimation of hormone delivery to tissues). First utilized at scale in the early 2000s and now commonly used by reference laboratories for automated serum hormone analysis.
Mass spectrometry (LCMS, GCMS, ICPMS) – utilizes different sample preparations to measure analytes, or fragments of analytes, via a mass/charge ratio. Gold standard for high sensitivity/specificity, extended linear range, and complex hormone analysis. Slow adoption due to cost of instrumentation and need for highly trained staff.
How to Use
Why We Partner with ZRT Laboratory
At Hormone Lab UK, every home test kit is analysed by ZRT Laboratory, a globally recognised, CLIA-certified diagnostic and research laboratory specialising in hormone testing, thyroid testing, fertility testing, adrenal function, neurotransmitter analysis, cardiometabolic health, heavy metals, and wellness testing. Founded in 1998 by renowned biochemist and breast cancer researcher Dr. David Zava, PhD, ZRT has become one of the world's leading laboratories for advanced functional health testing.
With more than 11 million laboratory tests performed and healthcare professionals in over 96 countries relying on its expertise, ZRT is recognised for scientific excellence, analytical accuracy, and continuous innovation. The laboratory pioneered at-home saliva hormone testing, introduced the first commercially available dried blood spot (DBS) hormone tests, and developed Dried Urine Testing (DUTS), helping make advanced laboratory diagnostics more accessible and clinically meaningful.
Every sample is analysed using state-of-the-art LC-MS/MS and ICP-MS technology under rigorous quality control standards, providing highly accurate, clinically reliable results. ZRT also collaborates with leading organisations, including the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), and major universities, supporting ongoing research and advances in laboratory medicine.
By partnering with ZRT Laboratory, Hormone Lab UK gives customers throughout the UK and Europe access to internationally trusted, research-backed laboratory testing that supports informed, personalised healthcare decisions.
