Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — Estrogen Dominance

When Hormones Shape the Mind Hormones are powerful chemical messengers that quietly influence not only our bodies but also our thoughts and emotions. While neurotransmitters like serotonin and dopamine often get the spotlight for controlling mood, science now shows that hormones can have just as much impact on mental well-being. 1. The Emotional Swing of Oestrogen and Progesterone Women often experience emotional changes before menstruation, after childbirth, or during menopause. These phases involve major shifts in oestrogen and progesterone. Before menstruation: Falling oestrogen can lower serotonin, leading to irritability or sadness. After childbirth: A sudden hormone drop can trigger postpartum...

By Dr. Sherry LaBeck of ZRT Lab Perimenopause is the transition between a woman's reproductive years and menopause, characterized by a decline in estrogen levels, which can lead to physical and emotional symptoms. Understanding the role of estrogen during this phase is essential for managing symptoms and improving the quality of life for women going through this transition. What is Perimenopause? Perimenopause typically begins in a woman's 40s, though some may experience symptoms as early as their mid-30s, which is known as premature menopause. During this phase, the ovaries produce less estrogen until menstruation stops, marking the onset of menopause....

Single nucleotide variations (SNVs) in the enzymes that metabolise estrogen can significantly alter breast cancer risk — in some cases by as much as 12-fold when multiple variants combine. In this detailed scientific overview, Jillian Harrington PhD of ZRT Laboratory explains how variations in CYP11A1, CYP19A1 (aromatase), CYP1B1, COMT and MnSOD affect the estrogen metabolism pathway, why catechol estrogens are dangerous, and how methylation testing can reveal individual vulnerability.

If you’re doing everything right — eating well, exercising, taking your vitamins — but still can’t shift the weight, a hormone imbalance may be working against you. Hormone Health Educator Candace Burch of ZRT Laboratory breaks down the 8 most common hormonal culprits behind unexplained weight gain, from estrogen dominance and high cortisol to low vitamin D, disrupted sleep and a lack of strength training.

Why does weight gain accelerate at menopause? Can estrogen dominance cause low cortisol? Is saliva testing better than blood? Hormone Health Educator Candace Burch of ZRT Laboratory answers the most common questions from women struggling with hormone-related weight gain — covering everything from adrenal fatigue and vitamin D deficiency to birth control, bioidentical progesterone and why “your hormones are fine” from a standard blood test may not tell the whole story.