This test evaluates whether the concentration of SHBG affects the amount of testosterone available to the body’s tissues.
The Sex Hormone Binding Globulin (SHBG) Test is designed to test for Sex Hormone Binding Globulin (SHBG), accurately assessing SHBG levels in the blood.
Sex Hormone Binding Globulin (SHBG) binds and transports both testosterone and estrogens in the bloodstream, and it, therefore, regulates the relative amounts of free and bound hormones and, consequently their bioavailability to target tissues. SHBG is a protein produced by the liver in response to exposure to any estrogen. Testosterone binds about three times more tightly to SHBG than does estradiol, so this increase in SHBG as a result of estrogen exposure causes the relative proportion of bioavailable testosterone to estradiol to decrease even further, exacerbating the symptoms of testosterone deficiency. Many factors, in addition to estrogen exposure, can affect SHBG levels. For example, thyroid hormone increases SHBG production, whereas insulin, on the other hand, decreases SHBG levels. In young men, testosterone levels are usually high and SHBG low, making most of the testosterone bioavailable. However, as men gain weight and estrogen levels increase, SHBG also rises, decreasing bioavailable testosterone. Measuring SHBG in the blood provides an indication of the overall exposure to estrogens, as well as the bioavailable (free) fraction of testosterone (calculated from the ratio of testosterone to SHBG).
Low SHGB levels:
- Excessive body hair/male-pattern hair growth (hirsutism)
- Acne
- Dandruff
- Baldness
- Voice deepening
- Increased muscle mass
- Reduced breast size
- Irregular or absent periods
We strongly recommend that you consult your test results with your health care provider, GP, or doctor to know whether or not any further actions need to be carried out and get started with ample treatment if needed.
Test Result: You will receive your test result 3-5 working days after the laboratory receives your sample. You will see your hormone levels in graphics and numbers on your test result. You will also see laboratory comments by a Hormone Specialist PhD Dr in the comments: you will find an analysis of your hormone levels and what to do next.
- Collect samples from the comfort of your home and post them to our lab.
- The test must be used within 12 months after the purchase date.
- The test kit includes a laboratory fee: no additional laboratory cost and tax.
- Customers are responsible for shipping their samples to the laboratory.
How does the test carry out?
This blood spot-based testing tool can be done in the privacy of your home. A simple step of collecting your blood spot for the test is required. Once you provide a blood spot, you need to seal the sample and send it off to us. Your test result report will be emailed to you between 3 and 5 working days after the laboratory receives your sample.
How to Use
