Male Comprehensive Hormone Profile I

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Male Comprehensive Hormone Profile I – Blood Spot Test (8 Hormones + SHBG)

Test ID: B-242M | At-Home Blood Spot Collection | Results in 3–5 Working Days

The Male Comprehensive Hormone Profile I is a clinically advanced, at-home blood spot hormone test designed specifically for men. It measures eight key hormones using highly accurate LC-MS/MS technology through our CLIA-certified partner laboratory, ZRT Laboratory. Whether you're experiencing symptoms of andropause, low testosterone, adrenal fatigue, or general hormonal imbalance, this test gives you the data you need to take control of your health.

What Does This Test Measure?

This panel tests the following eight essential hormones in men:

  • Estrone (E1) – an oestrogen that plays a role in male bone density and cardiovascular health
  • Estradiol (E2) – the primary oestrogen; elevated levels in men are linked to low libido and fat gain
  • Estriol (E3) – a weaker oestrogen that helps assess overall oestrogen balance
  • Progesterone (Pg) – supports testosterone production and counteracts oestrogen dominance
  • Testosterone (T) – the primary male sex hormone; critical for energy, muscle mass, libido, and mood
  • DHEA-S (DS) – an adrenal hormone that declines with age; linked to vitality and immune function
  • Cortisol (C) – the stress hormone; chronically elevated cortisol suppresses testosterone
  • Sex Hormone Binding Globulin (SHBG) – determines how much testosterone is biologically available

Who Is This Test For?

This test is ideal for men who are experiencing one or more of the following symptoms of hormonal imbalance:

  • Low libido or sexual dysfunction
  • Persistent fatigue and low energy
  • Loss of muscle mass or increased body fat
  • Mood swings, depression, or anxiety
  • Brain fog, poor concentration, or memory lapses
  • Sleep disturbances or insomnia
  • Hot flashes or night sweats (andropause symptoms)
  • Irritability, stress, or burnout
  • Decreased stamina or physical performance
  • Slow metabolism or unexplained weight gain

How Does the Test Work?

  1. Order your kit – delivered directly to your door across the UK
  2. Collect your sample at home – a simple finger-prick blood spot collection, no clinic visit required
  3. Post your sample – send it to our ZRT Laboratory using standard post (shipping cost is your responsibility)
  4. Receive your results – within 3–5 working days of the lab receiving your sample
  5. Review your report – detailed hormone level graphics, numerical values, and specialist commentary from a PhD Hormone Specialist Doctor

👉 View a Sample Test Result Report

What's Included in the Kit?

  • Blood spot collection card
  • Lancets for finger-prick sampling
  • Full instructions
  • Laboratory fee (no additional lab costs or hidden charges)
  • Valid for 12 months from purchase date

Why Test Your Hormones as a Man?

Male hormonal health is rarely a single-hormone issue. Testosterone, cortisol, DHEA-S, oestrogens, and SHBG all interact in a complex system — much like instruments in an orchestra. When one is out of balance, the entire system is affected. A comprehensive hormone profile gives you a full picture rather than a single data point, enabling more informed conversations with your GP or specialist.

Hormonal imbalance in men is often misdiagnosed or overlooked. Symptoms like fatigue, low mood, and weight gain are frequently attributed to lifestyle factors when the root cause may be hormonal. This test helps identify whether hormones are contributing to your symptoms.

Why We Use ZRT Laboratory

All testing is performed by ZRT Laboratory — a globally recognised, CLIA-certified diagnostic laboratory founded in 1998 by Dr. David Zava, PhD. ZRT has performed over 11 million tests and is trusted by healthcare professionals in 96+ countries.

  • Pioneers of at-home dried blood spot (DBS) hormone testing
  • Advanced LC-MS/MS and ICP-MS technology for clinical-grade accuracy
  • Qualified for the CDC Hormone Standardization (HoSt) Program for testosterone and estradiol
  • Personalised reference ranges based on age and sex

Through our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to men across the UK and Europe — from the comfort of home.