Test ID: S-125
Sample Type: Saliva
Technology: LC-MS/MS Advanced Laboratory Saliva Hormone Analysis
Results Time: 3–5 Working Days After Laboratory Receives Sample
Laboratory: ZRT Laboratory – CLIA Certified
Hormone Specialist Doctor Interpretation: Included
Suitable For: Adults and Children
The Male Saliva Hormone Profile III (LC-MS/MS) is an advanced at-home hormone test for men that measures seven essential hormones using LC-MS/MS — the gold-standard laboratory technique for high-precision hormone analysis. This test provides a clear and accurate picture of your hormonal health — including testosterone, DHEAS, progesterone, cortisol, and key oestrogens — all from a simple saliva sample collected at home.
What the Test Measures
- Testosterone (T): The main male hormone that supports muscle growth, bone density, libido, and vitality.
- DHEAS (DS): An adrenal hormone that converts into testosterone and oestrogen, reflecting overall hormonal balance.
- Progesterone (Pg): Plays a role in mood, brain function, and counterbalancing oestrogen effects in men.
- Cortisol (C): The stress hormone that regulates metabolism, immune response, and energy.
- Oestrone (E1): A type of oestrogen involved in bone and cardiovascular health.
- Oestradiol (E2): The most active form of oestrogen, essential for sexual and brain health in men.
- Oestriol (E3): A weaker form of oestrogen, valuable for understanding overall oestrogenic activity.
- How and when to collect your saliva samples: Saliva Testing Instructions
- Click to see >> Sample Saliva Test Result Report
Key Features
- Accurate LC-MS/MS Technology: Ensures high sensitivity and precision for detecting even low hormone concentrations.
- Comprehensive 7-Hormone Profile: Covers both male and adrenal hormones for a complete health assessment.
- At-Home Collection: Collect your saliva sample in minutes — no clinic visit required.
- Fast Results: Receive your detailed hormone report within 3–5 working days after the lab receives your sample.
- Expert Analysis: Includes PhD Hormone Specialist commentary and personalised guidance for optimal hormonal health.
- Actionable Insights: Identify deficiencies or excesses early to support better energy, mood, fertility, and stress management.
- Transparent Pricing: All lab fees included. No hidden charges — you only pay for shipping your sample.
- Confidential and Convenient: 100% private, non-invasive, and suitable for men of all ages.
Why Choose Saliva Testing?
- Non-Invasive: No needles or blood draws — just a simple saliva sample.
- Bioavailable Hormone Measurement: Accurately measures the active (unbound) hormones that affect how you feel.
- At-Home Collection: Easy sample collection at specific times for the most accurate results.
- Reliable for Monitoring Therapy: Ideal for tracking progress during hormone replacement or testosterone therapy.
What Your Results Include
- Graphical and numerical hormone values for clear interpretation
- PhD-level hormone specialist review and comments
- Personalised recommendations to restore and maintain optimal balance
Who Should Take This Test
This test is ideal for men who experience:
- Fatigue or low energy
- Decreased libido or erectile issues
- Weight gain or muscle loss
- Sleep problems or mood swings
- Stress or anxiety
- Hot flushes or night sweats
- Difficulty focusing or brain fog
How It Works
- Order Online: Choose your test and receive your kit at home.
- Collect Samples: Follow the step-by-step saliva collection instructions.
- Send to Lab: Mail your sample using the secure return envelope.
- Receive Results: Get your expert-reviewed report within 3–5 working days.
FAQ — Male Saliva Hormone Profile III (LC-MS/MS)
1. What does this test measure?
Seven key male hormones — testosterone, DHEAS, progesterone, cortisol, oestrone, oestradiol, and oestriol — using LC-MS/MS for high accuracy.
2. What is LC-MS/MS?
Liquid Chromatography–Tandem Mass Spectrometry — a precise lab method that detects even very low hormone levels with clinical-grade accuracy.
3. Who should take this test?
Men with fatigue, low libido, mood changes, stress, weight gain, or suspected hormonal imbalance.
4. How do I collect the sample?
Collect saliva at home using the provided kit and send it to our certified lab following the included instructions.
5. How long until I get results?
Results are ready within 3–5 working days after your sample arrives at the lab.
6. What's included in my results?
Graphical and numerical hormone values plus expert analysis and recommendations from a PhD Hormone Specialist.
7. Are there any extra fees?
No hidden charges — the lab fee is included. You only pay for sample postage.
8. Is the test suitable for all ages?
Yes, suitable for adult men and adolescents under clinical supervision.
9. Why choose saliva testing?
It's non-invasive, convenient, and measures bioavailable (active) hormones — the ones that truly affect how you feel.
What's the Difference Between Each Testing Method?
Enzyme Immunoassay (EIA) — antibody/antigen-based technology with moderate specificity and sensitivity, low cost, not ideal for complex hormone analysis.
Electrochemiluminescence (ECLIA) — improved specificity and sensitivity, commonly used for serum hormone analysis, but not ideal for topical hormone therapies.
Mass Spectrometry (LC-MS/MS) — gold standard for high sensitivity/specificity, extended linear range, and complex hormone analysis.
How to Use
Why We Partner with ZRT Laboratory
At Hormone Lab UK, every home test kit is analysed by ZRT Laboratory, a globally recognised, CLIA-certified diagnostic and research laboratory specialising in hormone testing, thyroid testing, fertility testing, adrenal function, neurotransmitter analysis, cardiometabolic health, heavy metals, and wellness testing. Founded in 1998 by renowned biochemist and breast cancer researcher Dr. David Zava, PhD, ZRT has become one of the world's leading laboratories for advanced functional health testing.
With more than 11 million laboratory tests performed and healthcare professionals in over 96 countries relying on its expertise, ZRT is recognised for scientific excellence, analytical accuracy, and continuous innovation. Every sample is analysed using state-of-the-art LC-MS/MS and ICP-MS technology under rigorous quality control standards. ZRT collaborates with the CDC, NIH, and leading universities, supporting ongoing research and advances in laboratory medicine.
