Test ID: B-240M | Sample Type: Dried Blood Spot | Test Method: LC-MS/MS | Results: 3–5 Working Days | Laboratory: ZRT Lab — CLIA Certified | Report: Specialist Doctor Comment Included
Could Low Testosterone or Oestrogen Imbalance Be Affecting Your Health?
Testosterone, oestrogen, and progesterone don’t operate in isolation in men — they interact constantly, and an imbalance in one affects the others. Symptoms are frequently dismissed as stress or ageing when the root cause may be hormonal. If you recognise any of the following, this panel could reveal what’s really going on:
Symptoms of low testosterone:
- Low libido or erectile dysfunction
- Persistent fatigue and low stamina
- Loss of muscle mass or increased body fat
- Anxiety, depression, or low mood
- Brain fog or forgetfulness
- Dry skin or reduced body hair
Symptoms of elevated oestrogen (E2) in men:
- Gynaecomastia (breast tissue growth)
- Increased abdominal fat
- Water retention or bloating
- Mood swings or irritability
- Decreased fertility
- Poor concentration or memory lapses
Symptoms of progesterone imbalance in men:
- Low testosterone (progesterone is a precursor)
- Increased oestrogen dominance
- Mood disturbances, anxiety, or sleep issues
- Decreased libido
Symptoms of SHBG imbalance:
- High SHBG: fatigue, low libido, muscle loss, depression — even when total testosterone appears normal
- Low SHBG: acne, hair loss, increased oestrogen conversion
What This Test Measures
This panel tests four core sex hormone markers using highly accurate LC-MS/MS technology:
- Testosterone (T) – The primary male sex hormone; critical for energy, muscle mass, libido, mood, and metabolic health
- Estradiol (E2) – Men produce oestrogen too; elevated E2 is linked to low libido, fat gain, and mood issues
- Progesterone (Pg) – Supports testosterone production and counteracts oestrogen dominance in men
- SHBG (Sex Hormone Binding Globulin) – Determines how much testosterone is biologically available; high SHBG can cause low-testosterone symptoms even when total testosterone appears normal
How It Works
- Order your kit — delivered to your door
- Collect your sample at home — a simple finger-prick blood spot; no clinic or GP visit needed
- Post your sample to our CLIA-certified laboratory using the instructions provided
- Receive your results by email within 3–5 working days of the lab receiving your sample
What You Get With Your Results
Your personalised report includes:
- All four hormone levels displayed clearly in graphics and numbers
- A written interpretation by a Hormone Specialist PhD Doctor
- Guidance on what your results mean and what to do next
View a Sample Test Result Report
Who Is This Test For?
This test is suitable for men who want to:
- Assess their core sex hormone balance in a single, convenient test
- Investigate symptoms of low testosterone, andropause, or oestrogen dominance
- Understand why symptoms persist despite “normal” standard blood tests
- Monitor hormone levels during or after TRT or other hormone therapy
- Get a specialist interpretation of testosterone, oestrogen, and progesterone together
Key Information
- Collect your sample from home and post to our lab — no clinic visit required
- Results delivered by email within 3–5 working days
- Laboratory fee included — no hidden costs or additional charges
- Valid for 12 months from the date of purchase
- Analysed by ZRT Laboratory — CLIA certified, using LC-MS/MS technology with over 11 million tests performed
- Customers are responsible for posting their sample to the laboratory
Why We Use ZRT Laboratory
All testing is performed by ZRT Laboratory — a globally recognised, CLIA-certified diagnostic laboratory founded in 1998 by Dr. David Zava, PhD. ZRT has performed over 11 million tests and is trusted by healthcare professionals in 96+ countries.
- Pioneers of at-home dried blood spot (DBS) hormone testing
- Advanced LC-MS/MS and ICP-MS technology for clinical-grade accuracy
- Qualified for the CDC Hormone Standardization (HoSt) Program for testosterone and estradiol
- Personalised reference ranges based on age and sex
Through our partnership with ZRT Laboratory, Hormone Lab UK delivers internationally recognised, research-backed hormone testing to men across the UK and Europe — from the comfort of home.
