Hormone Health Hub: Expert Insights on Testing, Balance & Better Living — Story of PCOS

By Dr Beth Baldwin, ZRT Lab We are living in an age of insulin resistance. Excessive intake of calories and refined carbohydrates decreased physical activity, and chronic stress increases insulin secretion and decreases insulin sensitivity. This creates a vicious circle of requiring more and more insulin to shuttle glucose into cells. Years or possibly even decades before the elevations in blood glucose and hemoglobin A1C associated with type 2 diabetes, fasting insulin increases, and this high insulin is at the core of metabolic syndrome and polycystic ovary syndrome (PCOS). Recently published research suggests that insulin resistance also doubles the risk...

When a patient with PCOS or weight issues is told “your blood sugar is normal,” the story is far from over. In this clinical article, Dr. Alison McAllister of ZRT Laboratory explains why insulin — not glucose — is the primary driver of PCOS symptoms, weight gain, testosterone and DHEAS excess, and cortisol dysfunction. Understanding the progression from insulin resistance to hyperinsulinemia to type 2 diabetes is essential for identifying and treating PCOS at the earliest possible stage.